Prognostic factors of poor postoperative outcomes in gastrectomies
BackgroundGastric cancer is one of the most common cancers worldwide and is the third most common cause of cancer related death. Improving postoperative results by understanding risk factors which impact outcomes is important. The current study aimed to compare immediate perioperative outcomes follo...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-12-01
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| Series: | Frontiers in Surgery |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fsurg.2023.1324247/full |
| _version_ | 1797434971017707520 |
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| author | B. O. Stüben G. A. Plitzko L. Stern J. Li J. P. Neuhaus J. W. Treckmann R. Schmeding F. H. Saner F. H. Saner D. P. Hoyer |
| author_facet | B. O. Stüben G. A. Plitzko L. Stern J. Li J. P. Neuhaus J. W. Treckmann R. Schmeding F. H. Saner F. H. Saner D. P. Hoyer |
| author_sort | B. O. Stüben |
| collection | DOAJ |
| description | BackgroundGastric cancer is one of the most common cancers worldwide and is the third most common cause of cancer related death. Improving postoperative results by understanding risk factors which impact outcomes is important. The current study aimed to compare immediate perioperative outcomes following gastrectomy.Methods302 patients following gastric resections over a 10-year period (January 2009–January 2020) were identified in a database and retrospectively analysed. Epidemiological as well as perioperative data was analysed, and a univariate and multivariate analysis performed to identify risk factors for in-hospital mortality.ResultsIn general, gastrectomies were mainly performed electively (total vs. subtotal 95% vs. 85%, p = 0.004). Patients having subtotal gastrectomy needed significantly more PRBC transfusions compared to total gastrectomy (p = 0.039). Most emergency surgeries were performed for benign diseases, such as ulcer perforations or bleeding and gastric ischaemia. Only emergency surgery was significantly associated with poorer overall survival (HR 2.68, 95% CI 1.32–5.05, p = 0.003).ConclusionIn-hospital mortality was comparable between total and subtotal gastrectomies. Only emergency interventions increased postoperative fatality risk. |
| first_indexed | 2024-03-09T10:40:36Z |
| format | Article |
| id | doaj.art-5f8e8d5adbed4127b738dd88fd7071e6 |
| institution | Directory Open Access Journal |
| issn | 2296-875X |
| language | English |
| last_indexed | 2024-03-09T10:40:36Z |
| publishDate | 2023-12-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Surgery |
| spelling | doaj.art-5f8e8d5adbed4127b738dd88fd7071e62023-12-01T14:21:47ZengFrontiers Media S.A.Frontiers in Surgery2296-875X2023-12-011010.3389/fsurg.2023.13242471324247Prognostic factors of poor postoperative outcomes in gastrectomiesB. O. Stüben0G. A. Plitzko1L. Stern2J. Li3J. P. Neuhaus4J. W. Treckmann5R. Schmeding6F. H. Saner7F. H. Saner8D. P. Hoyer9Department of General, Visceral and Transplant Surgery, Medical Centre University Duisburg-Essen, Essen, GermanyDepartment of General, Visceral and Thoracic Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, GermanyDepartment of General, Visceral and Thoracic Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, GermanyDepartment of Surgery, Jiahui International Hospital, Shanghai, ChinaDepartment of General, Visceral and Transplant Surgery, Medical Centre University Duisburg-Essen, Essen, GermanyDepartment of General, Visceral and Transplant Surgery, Medical Centre University Duisburg-Essen, Essen, GermanyDepartment of General, Visceral and Transplant Surgery, Medical Centre University Duisburg-Essen, Essen, GermanyDepartment of General, Visceral and Transplant Surgery, Medical Centre University Duisburg-Essen, Essen, GermanyOrgan Transplant Center of Excellence, King Faisal Specialist Hospital & Research Center, Riyadh, Saudi ArabiaDepartment of General, Visceral and Transplant Surgery, Medical Centre University Duisburg-Essen, Essen, GermanyBackgroundGastric cancer is one of the most common cancers worldwide and is the third most common cause of cancer related death. Improving postoperative results by understanding risk factors which impact outcomes is important. The current study aimed to compare immediate perioperative outcomes following gastrectomy.Methods302 patients following gastric resections over a 10-year period (January 2009–January 2020) were identified in a database and retrospectively analysed. Epidemiological as well as perioperative data was analysed, and a univariate and multivariate analysis performed to identify risk factors for in-hospital mortality.ResultsIn general, gastrectomies were mainly performed electively (total vs. subtotal 95% vs. 85%, p = 0.004). Patients having subtotal gastrectomy needed significantly more PRBC transfusions compared to total gastrectomy (p = 0.039). Most emergency surgeries were performed for benign diseases, such as ulcer perforations or bleeding and gastric ischaemia. Only emergency surgery was significantly associated with poorer overall survival (HR 2.68, 95% CI 1.32–5.05, p = 0.003).ConclusionIn-hospital mortality was comparable between total and subtotal gastrectomies. Only emergency interventions increased postoperative fatality risk.https://www.frontiersin.org/articles/10.3389/fsurg.2023.1324247/fullgastrectomymortalitymorbidityemergency surgerysubtotal gastrectomy |
| spellingShingle | B. O. Stüben G. A. Plitzko L. Stern J. Li J. P. Neuhaus J. W. Treckmann R. Schmeding F. H. Saner F. H. Saner D. P. Hoyer Prognostic factors of poor postoperative outcomes in gastrectomies Frontiers in Surgery gastrectomy mortality morbidity emergency surgery subtotal gastrectomy |
| title | Prognostic factors of poor postoperative outcomes in gastrectomies |
| title_full | Prognostic factors of poor postoperative outcomes in gastrectomies |
| title_fullStr | Prognostic factors of poor postoperative outcomes in gastrectomies |
| title_full_unstemmed | Prognostic factors of poor postoperative outcomes in gastrectomies |
| title_short | Prognostic factors of poor postoperative outcomes in gastrectomies |
| title_sort | prognostic factors of poor postoperative outcomes in gastrectomies |
| topic | gastrectomy mortality morbidity emergency surgery subtotal gastrectomy |
| url | https://www.frontiersin.org/articles/10.3389/fsurg.2023.1324247/full |
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