Caveolin-1 protects B6129 mice against Helicobacter pylori gastritis.

Caveolin-1 protects B6129 mice against Helicobacter pylori gastritis.

Caveolin-1 (Cav1) is a scaffold protein and pathogen receptor in the mucosa of the gastrointestinal tract. Chronic infection of gastric epithelial cells by Helicobacter pylori (H. pylori) is a major risk factor for human gastric cancer (GC) where Cav1 is frequently down-regulated. However, the funct...

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Main Authors: Ivana Hitkova, Gang Yuan, Florian Anderl, Markus Gerhard, Thomas Kirchner, Simone Reu, Christoph Röcken, Claus Schäfer, Roland M Schmid, Roger Vogelmann, Matthias P A Ebert, Elke Burgermeister
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3623771?pdf=render

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