Nosocomial outbreak of severe fever with thrombocytopenia syndrome among healthcare workers in a single hospital in Daegu, Korea
Background: In August 2020, 17 healthcare workers (HCWs) were simultaneously diagnosed with severe fever with thrombocytopenia syndrome (SFTS) at a university hospital in Daegu, Republic of Korea. Methods: An epidemiologic investigation using questionnaires was conducted for all suspected HCWs who h...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2022-06-01
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| Series: | International Journal of Infectious Diseases |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1201971222001850 |
| _version_ | 1818271007310348288 |
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| author | Sohyun Bae Hyun-Ha Chang Shin-Woo Kim Yoonjung Kim EunByeol Wang Chi Kyeong Kim Eunji Choi Bohyun Lim Sookkyung Park Hwajin Chae Hyeyoung Jeon |
| author_facet | Sohyun Bae Hyun-Ha Chang Shin-Woo Kim Yoonjung Kim EunByeol Wang Chi Kyeong Kim Eunji Choi Bohyun Lim Sookkyung Park Hwajin Chae Hyeyoung Jeon |
| author_sort | Sohyun Bae |
| collection | DOAJ |
| description | Background: In August 2020, 17 healthcare workers (HCWs) were simultaneously diagnosed with severe fever with thrombocytopenia syndrome (SFTS) at a university hospital in Daegu, Republic of Korea. Methods: An epidemiologic investigation using questionnaires was conducted for all suspected HCWs who had viral infection symptoms or who had the possibility of exposure to the index patient. Results: A total of 17 HCWs infected with the SFTS virus (SFTSV) (28.8%) were identified among the 59 HCWs who had contact with the patient. Operating a bag valve mask during cardiopulmonary resuscitation (CPR) (OR 7.50, 95% CI 1.75–41.07), cardiac massage during CPR (OR 12.00, 95% CI 1.76–241.94), exposure to the patient's body fluids (OR 7.43, 95% CI 1.91–34.69), and shorter individual hospital work experience periods (OR 6.79, 95% CI 1.70–32.10) were significantly associated with SFTS infection in the univariate analysis. However, exposure to body fluids was found to be the only statistically significant risk factor when multivariate analysis was conducted (OR 6.27. 95% CI 1.23–42.81, p = 0.036). Conclusions: This finding illustrates the importance of wearing appropriate personal protective equipment in treatment areas and when conducting any medical procedures, including CPR for patients with SFTS, and any procedure that involves potential exposure to body fluids. |
| first_indexed | 2024-12-12T21:19:19Z |
| format | Article |
| id | doaj.art-5f91d0b5997f4b7f9e59f6b937a7df26 |
| institution | Directory Open Access Journal |
| issn | 1201-9712 |
| language | English |
| last_indexed | 2024-12-12T21:19:19Z |
| publishDate | 2022-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | International Journal of Infectious Diseases |
| spelling | doaj.art-5f91d0b5997f4b7f9e59f6b937a7df262022-12-22T00:11:38ZengElsevierInternational Journal of Infectious Diseases1201-97122022-06-0111995101Nosocomial outbreak of severe fever with thrombocytopenia syndrome among healthcare workers in a single hospital in Daegu, KoreaSohyun Bae0Hyun-Ha Chang1Shin-Woo Kim2Yoonjung Kim3EunByeol Wang4Chi Kyeong Kim5Eunji Choi6Bohyun Lim7Sookkyung Park8Hwajin Chae9Hyeyoung Jeon10Division of Infectious Diseases, Department of Internal Medicine, Kyungpook National University Hospital, School of Medicine, Kyungpook National University, Daegu, KoreaDivision of Infectious Diseases, Department of Internal Medicine, Kyungpook National University Hospital, School of Medicine, Kyungpook National University, Daegu, KoreaDivision of Infectious Diseases, Department of Internal Medicine, Kyungpook National University Hospital, School of Medicine, Kyungpook National University, Daegu, Korea; Corresponding author: Shin-Woo Kim, MD, PhD Department of Internal Medicine, Kyungpook National University Hospital, School of Medicine, Kyungpook National University, 130 Dongdeok-ro, Jung-gu, Daegu, Korea, 41944Division of Infectious Diseases, Department of Internal Medicine, Kyungpook National University Hospital, School of Medicine, Kyungpook National University, Daegu, KoreaDivision of Viral diseases, Korea Disease Control and Prevention AgencyDivision of Viral diseases, Korea Disease Control and Prevention AgencyDivision of Viral diseases, Korea Disease Control and Prevention AgencyDivision of Control for Zoonotic and Vector borne Disease, Korea Disease Control and Prevention AgencyDivision of Control for Zoonotic and Vector borne Disease, Korea Disease Control and Prevention AgencyInfection Control Office, Kyungpook National University Hospital, Daegu, KoreaInfection Control Office, Kyungpook National University Hospital, Daegu, KoreaBackground: In August 2020, 17 healthcare workers (HCWs) were simultaneously diagnosed with severe fever with thrombocytopenia syndrome (SFTS) at a university hospital in Daegu, Republic of Korea. Methods: An epidemiologic investigation using questionnaires was conducted for all suspected HCWs who had viral infection symptoms or who had the possibility of exposure to the index patient. Results: A total of 17 HCWs infected with the SFTS virus (SFTSV) (28.8%) were identified among the 59 HCWs who had contact with the patient. Operating a bag valve mask during cardiopulmonary resuscitation (CPR) (OR 7.50, 95% CI 1.75–41.07), cardiac massage during CPR (OR 12.00, 95% CI 1.76–241.94), exposure to the patient's body fluids (OR 7.43, 95% CI 1.91–34.69), and shorter individual hospital work experience periods (OR 6.79, 95% CI 1.70–32.10) were significantly associated with SFTS infection in the univariate analysis. However, exposure to body fluids was found to be the only statistically significant risk factor when multivariate analysis was conducted (OR 6.27. 95% CI 1.23–42.81, p = 0.036). Conclusions: This finding illustrates the importance of wearing appropriate personal protective equipment in treatment areas and when conducting any medical procedures, including CPR for patients with SFTS, and any procedure that involves potential exposure to body fluids.http://www.sciencedirect.com/science/article/pii/S1201971222001850Severe fever with thrombocytopenia syndromeNosocomial transmissionHealthcare worker |
| spellingShingle | Sohyun Bae Hyun-Ha Chang Shin-Woo Kim Yoonjung Kim EunByeol Wang Chi Kyeong Kim Eunji Choi Bohyun Lim Sookkyung Park Hwajin Chae Hyeyoung Jeon Nosocomial outbreak of severe fever with thrombocytopenia syndrome among healthcare workers in a single hospital in Daegu, Korea International Journal of Infectious Diseases Severe fever with thrombocytopenia syndrome Nosocomial transmission Healthcare worker |
| title | Nosocomial outbreak of severe fever with thrombocytopenia syndrome among healthcare workers in a single hospital in Daegu, Korea |
| title_full | Nosocomial outbreak of severe fever with thrombocytopenia syndrome among healthcare workers in a single hospital in Daegu, Korea |
| title_fullStr | Nosocomial outbreak of severe fever with thrombocytopenia syndrome among healthcare workers in a single hospital in Daegu, Korea |
| title_full_unstemmed | Nosocomial outbreak of severe fever with thrombocytopenia syndrome among healthcare workers in a single hospital in Daegu, Korea |
| title_short | Nosocomial outbreak of severe fever with thrombocytopenia syndrome among healthcare workers in a single hospital in Daegu, Korea |
| title_sort | nosocomial outbreak of severe fever with thrombocytopenia syndrome among healthcare workers in a single hospital in daegu korea |
| topic | Severe fever with thrombocytopenia syndrome Nosocomial transmission Healthcare worker |
| url | http://www.sciencedirect.com/science/article/pii/S1201971222001850 |
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