Late diagnosis of respiratory syncytial virus and influenza co-infection during coronavirus disease 2019 pandemic: a case report
Abstract Background Respiratory syncytial virus (RSV)-induced disease is one of the important causes of flu-like illness in older adults and can cause serious disease in those who are at high-risk medical conditions. During coronavirus disease 2019 (COVID-19) pandemic, because of overlapping symptom...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2023-10-01
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| Series: | Journal of Medical Case Reports |
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| Online Access: | https://doi.org/10.1186/s13256-023-04187-3 |
| _version_ | 1797452512533413888 |
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| author | Elham Barahimi Mehdi Hassani Azad Zahra Ghaeini Hesarooeyeh Niloofar Hosseini Hafshejani Sahar Defaee Narjes Seddighi |
| author_facet | Elham Barahimi Mehdi Hassani Azad Zahra Ghaeini Hesarooeyeh Niloofar Hosseini Hafshejani Sahar Defaee Narjes Seddighi |
| author_sort | Elham Barahimi |
| collection | DOAJ |
| description | Abstract Background Respiratory syncytial virus (RSV)-induced disease is one of the important causes of flu-like illness in older adults and can cause serious disease in those who are at high-risk medical conditions. During coronavirus disease 2019 (COVID-19) pandemic, because of overlapping symptoms of severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) infection with other respiratory infections, diagnosing diseases based on clinical and radiological findings was challenging and could cause misdiagnosis. Case presentation An 87-year-old Persian man was admitted to the hospital due to loss of consciousness, respiratory distress, tachypnea, and oliguria. He had previously hospitalized because of cough, fever, loss of appetite, and fatigue. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) polymerase chain reaction (PCR) test was performed which was negative; however, based on ground glass opacity on his chest computed tomography (CT) scan and being on the outbreak of COVID-19, he fulfilled case definition of COVID-19; therefore, he received protocol’s treatment (remdesivir) for COVID-19 and relatively recovered and discharged. In our center, we requested brain and chest CT scans, blood tests, and multiplex PCR. Multiplex PCR revealed co-infection of influenza virus and RSV. Although we had started pneumonia and sepsis treatment, old age, weak immune system and the delay in initiation of right antibiotic and antivirus therapy altogether led him to die. Conclusion As a takeaway lesson of this case report, it is necessary to pay attention to viruses that show similar symptoms during future specific virus pandemics, especially in patients with old age and weak immune systems. |
| first_indexed | 2024-03-09T15:09:45Z |
| format | Article |
| id | doaj.art-5f9265ba2e044b80a74bcc4e4dd4785c |
| institution | Directory Open Access Journal |
| issn | 1752-1947 |
| language | English |
| last_indexed | 2024-03-09T15:09:45Z |
| publishDate | 2023-10-01 |
| publisher | BMC |
| record_format | Article |
| series | Journal of Medical Case Reports |
| spelling | doaj.art-5f9265ba2e044b80a74bcc4e4dd4785c2023-11-26T13:26:14ZengBMCJournal of Medical Case Reports1752-19472023-10-011711510.1186/s13256-023-04187-3Late diagnosis of respiratory syncytial virus and influenza co-infection during coronavirus disease 2019 pandemic: a case reportElham Barahimi0Mehdi Hassani Azad1Zahra Ghaeini Hesarooeyeh2Niloofar Hosseini Hafshejani3Sahar Defaee4Narjes Seddighi5Infectious and Tropical Diseases Research Center, Hormozgan Health Institute, Hormozgan University of Medical SciencesInfectious and Tropical Diseases Research Center, Hormozgan Health Institute, Hormozgan University of Medical SciencesStudent Research Committee, Faculty of Medicine, Hormozgan University of Medical SciencesStudent Research Committee, Faculty of Medicine, Hormozgan University of Medical SciencesInternal Medicine Department, Shahid Mohammadi Hospital, Hormozgan University of Medical SciencesStudent Research Committee, Faculty of Para-Medicine, Hormozgan University of Medical SciencesAbstract Background Respiratory syncytial virus (RSV)-induced disease is one of the important causes of flu-like illness in older adults and can cause serious disease in those who are at high-risk medical conditions. During coronavirus disease 2019 (COVID-19) pandemic, because of overlapping symptoms of severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) infection with other respiratory infections, diagnosing diseases based on clinical and radiological findings was challenging and could cause misdiagnosis. Case presentation An 87-year-old Persian man was admitted to the hospital due to loss of consciousness, respiratory distress, tachypnea, and oliguria. He had previously hospitalized because of cough, fever, loss of appetite, and fatigue. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) polymerase chain reaction (PCR) test was performed which was negative; however, based on ground glass opacity on his chest computed tomography (CT) scan and being on the outbreak of COVID-19, he fulfilled case definition of COVID-19; therefore, he received protocol’s treatment (remdesivir) for COVID-19 and relatively recovered and discharged. In our center, we requested brain and chest CT scans, blood tests, and multiplex PCR. Multiplex PCR revealed co-infection of influenza virus and RSV. Although we had started pneumonia and sepsis treatment, old age, weak immune system and the delay in initiation of right antibiotic and antivirus therapy altogether led him to die. Conclusion As a takeaway lesson of this case report, it is necessary to pay attention to viruses that show similar symptoms during future specific virus pandemics, especially in patients with old age and weak immune systems.https://doi.org/10.1186/s13256-023-04187-3RSVInfluenzaCOVID-19Case report |
| spellingShingle | Elham Barahimi Mehdi Hassani Azad Zahra Ghaeini Hesarooeyeh Niloofar Hosseini Hafshejani Sahar Defaee Narjes Seddighi Late diagnosis of respiratory syncytial virus and influenza co-infection during coronavirus disease 2019 pandemic: a case report Journal of Medical Case Reports RSV Influenza COVID-19 Case report |
| title | Late diagnosis of respiratory syncytial virus and influenza co-infection during coronavirus disease 2019 pandemic: a case report |
| title_full | Late diagnosis of respiratory syncytial virus and influenza co-infection during coronavirus disease 2019 pandemic: a case report |
| title_fullStr | Late diagnosis of respiratory syncytial virus and influenza co-infection during coronavirus disease 2019 pandemic: a case report |
| title_full_unstemmed | Late diagnosis of respiratory syncytial virus and influenza co-infection during coronavirus disease 2019 pandemic: a case report |
| title_short | Late diagnosis of respiratory syncytial virus and influenza co-infection during coronavirus disease 2019 pandemic: a case report |
| title_sort | late diagnosis of respiratory syncytial virus and influenza co infection during coronavirus disease 2019 pandemic a case report |
| topic | RSV Influenza COVID-19 Case report |
| url | https://doi.org/10.1186/s13256-023-04187-3 |
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