Visual Analysis and Focused Areas of Immunotherapy for Liver Cancer Based on Literature Data
Objective To compare the research status and hotspots of immunotherapy for liver cancer at home and abroad. Methods Papers about immunotherapy for liver cancer published from the establishment to 2019 were searched in PubMed database and Chinese database. Information were extracted and sorted by BIC...
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Format: | Article |
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Magazine House of Cancer Research on Prevention and Treatment
2021-10-01
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Series: | Zhongliu Fangzhi Yanjiu |
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Online Access: | http://html.rhhz.net/ZLFZYJ/html/8578.2020.21.0541.htm |
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author | YANG Xi CHU Yaojuan CHEN Juanjuan YANG Ting LIU Chong ZHANG Rui DU Shuzhang |
author_facet | YANG Xi CHU Yaojuan CHEN Juanjuan YANG Ting LIU Chong ZHANG Rui DU Shuzhang |
author_sort | YANG Xi |
collection | DOAJ |
description | Objective To compare the research status and hotspots of immunotherapy for liver cancer at home and abroad. Methods Papers about immunotherapy for liver cancer published from the establishment to 2019 were searched in PubMed database and Chinese database. Information were extracted and sorted by BICOMB-2 software, and then we created the word matrix and co-occurrence matrix of high-frequency subject headings. The cluster analysis of subject headings was conducted by gCLUTO 1.0. NetDraw 2.089 was used to draw social network diagrams, UCINET 6.212 was used to conduct the centrality analysis. Results There were 2 081 foreign literatures and 901 Chinese literatures, involving 655 foreign periodicals and 275 Chinese periodicals. Four themes of immunotherapy for liver cancer were determined: the correlation between the immune inoculation of hepatitis B patients and the occurrence of liver cancer, the study between dendritic cells and immunotherapy for liver cancer, the study of the combination of radiotherapy and immunotherapy on liver cancer, and related research of natural killer cells and liver cancer immunotherapy. Conclusion The number of researches on immunotherapy for liver cancer have shown an increasing trend year by year. We can learn from the international research status and hotspots to create a new way for liver cancer treatment. |
first_indexed | 2024-12-17T10:25:47Z |
format | Article |
id | doaj.art-5f92aabe29ec496baad32581ae155608 |
institution | Directory Open Access Journal |
issn | 1000-8578 |
language | zho |
last_indexed | 2024-12-17T10:25:47Z |
publishDate | 2021-10-01 |
publisher | Magazine House of Cancer Research on Prevention and Treatment |
record_format | Article |
series | Zhongliu Fangzhi Yanjiu |
spelling | doaj.art-5f92aabe29ec496baad32581ae1556082022-12-21T21:52:39ZzhoMagazine House of Cancer Research on Prevention and TreatmentZhongliu Fangzhi Yanjiu1000-85782021-10-01481096396910.3971/j.issn.1000-8578.2021.21.05418578.2020.21.0541Visual Analysis and Focused Areas of Immunotherapy for Liver Cancer Based on Literature DataYANG Xi0CHU Yaojuan1CHEN Juanjuan2YANG Ting3LIU Chong4ZHANG Rui5DU Shuzhang6Department of Pharmacy, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, ChinaDepartment of Pharmacy, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, ChinaDepartment of Pharmacy, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, ChinaDepartment of Pharmacy, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, ChinaDepartment of Pharmacy, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, ChinaDepartment of Pharmacy, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, ChinaDepartment of Pharmacy, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, ChinaObjective To compare the research status and hotspots of immunotherapy for liver cancer at home and abroad. Methods Papers about immunotherapy for liver cancer published from the establishment to 2019 were searched in PubMed database and Chinese database. Information were extracted and sorted by BICOMB-2 software, and then we created the word matrix and co-occurrence matrix of high-frequency subject headings. The cluster analysis of subject headings was conducted by gCLUTO 1.0. NetDraw 2.089 was used to draw social network diagrams, UCINET 6.212 was used to conduct the centrality analysis. Results There were 2 081 foreign literatures and 901 Chinese literatures, involving 655 foreign periodicals and 275 Chinese periodicals. Four themes of immunotherapy for liver cancer were determined: the correlation between the immune inoculation of hepatitis B patients and the occurrence of liver cancer, the study between dendritic cells and immunotherapy for liver cancer, the study of the combination of radiotherapy and immunotherapy on liver cancer, and related research of natural killer cells and liver cancer immunotherapy. Conclusion The number of researches on immunotherapy for liver cancer have shown an increasing trend year by year. We can learn from the international research status and hotspots to create a new way for liver cancer treatment.http://html.rhhz.net/ZLFZYJ/html/8578.2020.21.0541.htmliver cancerimmunotherapyvisual analysisbibliometric analysis |
spellingShingle | YANG Xi CHU Yaojuan CHEN Juanjuan YANG Ting LIU Chong ZHANG Rui DU Shuzhang Visual Analysis and Focused Areas of Immunotherapy for Liver Cancer Based on Literature Data Zhongliu Fangzhi Yanjiu liver cancer immunotherapy visual analysis bibliometric analysis |
title | Visual Analysis and Focused Areas of Immunotherapy for Liver Cancer Based on Literature Data |
title_full | Visual Analysis and Focused Areas of Immunotherapy for Liver Cancer Based on Literature Data |
title_fullStr | Visual Analysis and Focused Areas of Immunotherapy for Liver Cancer Based on Literature Data |
title_full_unstemmed | Visual Analysis and Focused Areas of Immunotherapy for Liver Cancer Based on Literature Data |
title_short | Visual Analysis and Focused Areas of Immunotherapy for Liver Cancer Based on Literature Data |
title_sort | visual analysis and focused areas of immunotherapy for liver cancer based on literature data |
topic | liver cancer immunotherapy visual analysis bibliometric analysis |
url | http://html.rhhz.net/ZLFZYJ/html/8578.2020.21.0541.htm |
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