Mechanism of Action of N‑Acyl and N‑Alkoxy Fosmidomycin Analogs: Mono- and Bisubstrate Inhibition of IspC from Plasmodium falciparum, a Causative Agent of Malaria

Bibliographic Details
Main Authors: Misgina B. Girma, Haley S. Ball, Xu Wang, Robert C. Brothers, Emily R. Jackson, Marvin J. Meyers, Cynthia S. Dowd, Robin D. Couch
Format: Article
Language:English
Published: American Chemical Society 2021-10-01
Series:ACS Omega
Online Access:https://doi.org/10.1021/acsomega.1c01711
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author Misgina B. Girma
Haley S. Ball
Xu Wang
Robert C. Brothers
Emily R. Jackson
Marvin J. Meyers
Cynthia S. Dowd
Robin D. Couch
author_facet Misgina B. Girma
Haley S. Ball
Xu Wang
Robert C. Brothers
Emily R. Jackson
Marvin J. Meyers
Cynthia S. Dowd
Robin D. Couch
author_sort Misgina B. Girma
collection DOAJ
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spelling doaj.art-5f9312837951499b909e15c7c9b48c542022-12-21T22:58:01ZengAmerican Chemical SocietyACS Omega2470-13432021-10-01642276302763910.1021/acsomega.1c01711Mechanism of Action of N‑Acyl and N‑Alkoxy Fosmidomycin Analogs: Mono- and Bisubstrate Inhibition of IspC from Plasmodium falciparum, a Causative Agent of MalariaMisgina B. Girma0Haley S. Ball1Xu Wang2Robert C. Brothers3Emily R. Jackson4Marvin J. Meyers5Cynthia S. Dowd6Robin D. Couch7Department of Chemistry and Biochemistry, George Mason University, Manassas, Virginia, United StatesDepartment of Chemistry and Biochemistry, George Mason University, Manassas, Virginia, United StatesProgenra Inc., Malvern, Pennsylvania, United StatesDepartment of Chemistry, The George Washington University, Washington, District of Columbia, United StatesDepartment of Chemistry, The George Washington University, Washington, District of Columbia, United StatesDepartment of Chemistry, Saint Louis University, Saint Louis, Missouri, United StatesDepartment of Chemistry, The George Washington University, Washington, District of Columbia, United StatesDepartment of Chemistry and Biochemistry, George Mason University, Manassas, Virginia, United Stateshttps://doi.org/10.1021/acsomega.1c01711
spellingShingle Misgina B. Girma
Haley S. Ball
Xu Wang
Robert C. Brothers
Emily R. Jackson
Marvin J. Meyers
Cynthia S. Dowd
Robin D. Couch
Mechanism of Action of N‑Acyl and N‑Alkoxy Fosmidomycin Analogs: Mono- and Bisubstrate Inhibition of IspC from Plasmodium falciparum, a Causative Agent of Malaria
ACS Omega
title Mechanism of Action of N‑Acyl and N‑Alkoxy Fosmidomycin Analogs: Mono- and Bisubstrate Inhibition of IspC from Plasmodium falciparum, a Causative Agent of Malaria
title_full Mechanism of Action of N‑Acyl and N‑Alkoxy Fosmidomycin Analogs: Mono- and Bisubstrate Inhibition of IspC from Plasmodium falciparum, a Causative Agent of Malaria
title_fullStr Mechanism of Action of N‑Acyl and N‑Alkoxy Fosmidomycin Analogs: Mono- and Bisubstrate Inhibition of IspC from Plasmodium falciparum, a Causative Agent of Malaria
title_full_unstemmed Mechanism of Action of N‑Acyl and N‑Alkoxy Fosmidomycin Analogs: Mono- and Bisubstrate Inhibition of IspC from Plasmodium falciparum, a Causative Agent of Malaria
title_short Mechanism of Action of N‑Acyl and N‑Alkoxy Fosmidomycin Analogs: Mono- and Bisubstrate Inhibition of IspC from Plasmodium falciparum, a Causative Agent of Malaria
title_sort mechanism of action of n acyl and n alkoxy fosmidomycin analogs mono and bisubstrate inhibition of ispc from plasmodium falciparum a causative agent of malaria
url https://doi.org/10.1021/acsomega.1c01711
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