Antimicrobial Electrospun Fibers of Polyester Loaded with Engineered Cyclic Gramicidin Analogues

Antimicrobial Electrospun Fibers of Polyester Loaded with Engineered Cyclic Gramicidin Analogues

Biodegradable polyester fibers have been loaded with two engineered analogues of gramicidin soviet. In these cyclic peptide derivatives, which were designed in a previous work to stabilize the bioactive conformation while enhancing the antimicrobial activity, the D-Phe was replaced by D-Pro, and the...

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Bibliographic Details
Main Authors: Silvana Maione, Luis Javier del Valle, Maria M. Pérez-Madrigal, Carlos Cativiela, Jordi Puiggalí, Carlos Alemán
Format: Article
Language:English
Published: MDPI AG 2017-09-01
Series:Fibers
Subjects:
biocompatibility
conformational restrictions
encapsulation
electrospinning
engineered peptides
hydrophobic peptides
Online Access:https://www.mdpi.com/2079-6439/5/3/34

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