Seroepidemiological study on the spread of SARS-CoV-2 in populations in especially affected areas in Germany – Study protocol of the CORONA-MONITORING lokal study

At a regional and local level, the COVID-19 pandemic has not spread out uniformly and some German municipalities have been particularly affected. The seroepidemiological data from these areas helps estimate the proportion of the population that has been infected with SARS-CoV-2 (seroprevalence), as...

Full description

Bibliographic Details
Main Authors: Claudia Santos-Hövener, Markus A. Busch, Carmen Koschollek, Martin Schlaud, Jens Hoebel, Robert Hoffmann, Hendrik Wilking, Sebastian Haller, Jennifer Allen, Jörg Wernitz, Hans Butschalowsky, Tim Kuttig, Silke Stahlberg, Julia Strandmark, Angelika Schaffrath Rosario, Antje Gößwald, Andreas Nitsche, Osamah Hamouda, Christian Drosten, Victor Corman, Lothar H. Wieler, Lars Schaade, Thomas Lampert
Format: Article
Language:deu
Published: Robert Koch Institute 2020-11-01
Series:Journal of Health Monitoring
Subjects:
Online Access:https://www.rki.de/EN/Content/Health_Monitoring/Health_Reporting/GBEDownloadsJ/JoHM_S5_2020_Study_protocol_CORONA_MONITORING_lokal.pdf?__blob=publicationFile
_version_ 1827294894924759040
author Claudia Santos-Hövener
Markus A. Busch
Carmen Koschollek
Martin Schlaud
Jens Hoebel
Robert Hoffmann
Hendrik Wilking
Sebastian Haller
Jennifer Allen
Jörg Wernitz
Hans Butschalowsky
Tim Kuttig
Silke Stahlberg
Julia Strandmark
Angelika Schaffrath Rosario
Antje Gößwald
Andreas Nitsche
Osamah Hamouda
Christian Drosten
Victor Corman
Lothar H. Wieler
Lars Schaade
Thomas Lampert
author_facet Claudia Santos-Hövener
Markus A. Busch
Carmen Koschollek
Martin Schlaud
Jens Hoebel
Robert Hoffmann
Hendrik Wilking
Sebastian Haller
Jennifer Allen
Jörg Wernitz
Hans Butschalowsky
Tim Kuttig
Silke Stahlberg
Julia Strandmark
Angelika Schaffrath Rosario
Antje Gößwald
Andreas Nitsche
Osamah Hamouda
Christian Drosten
Victor Corman
Lothar H. Wieler
Lars Schaade
Thomas Lampert
author_sort Claudia Santos-Hövener
collection DOAJ
description At a regional and local level, the COVID-19 pandemic has not spread out uniformly and some German municipalities have been particularly affected. The seroepidemiological data from these areas helps estimate the proportion of the population that has been infected with SARS-CoV-2 (seroprevalence), as well as the number of undetected infections and asymptomatic cases. In four municipalities which were especially affected, 2,000 participants will be tested for an active SARS-CoV-2 infection (oropharyngeal swab) or a past infection (blood specimen IgG antibody test). Participants will also be asked to fill out a short written questionnaire at study centres and complete a follow-up questionnaire either online or by telephone, including information on issues such as possible exposure, susceptability, symptoms and medical history. The CORONA-MONITORING lokal study will allow to determine the proportion of the population with SARS-CoV-2 antibodies in four particularly affected locations. This study will increase the accuracy of estimates regarding the scope of the epidemic, help determine risk and protective factors for an infection and therefore also identify especially exposed groups and, as such, it will be crucial towards planning of prevention measures.
first_indexed 2024-03-07T23:19:53Z
format Article
id doaj.art-5f99eab13377446981e1d22bc0c7f3ea
institution Directory Open Access Journal
issn 2511-2708
language deu
last_indexed 2024-04-24T14:10:51Z
publishDate 2020-11-01
publisher Robert Koch Institute
record_format Article
series Journal of Health Monitoring
spelling doaj.art-5f99eab13377446981e1d22bc0c7f3ea2024-04-03T09:14:48ZdeuRobert Koch InstituteJournal of Health Monitoring2511-27082020-11-015S521610.25646/7053johm-5-S5-02Seroepidemiological study on the spread of SARS-CoV-2 in populations in especially affected areas in Germany – Study protocol of the CORONA-MONITORING lokal studyClaudia Santos-Hövener0Markus A. Busch1Carmen Koschollek2Martin Schlaud3Jens Hoebel4Robert Hoffmann5Hendrik Wilking6Sebastian Haller7Jennifer Allen8Jörg Wernitz9Hans Butschalowsky10Tim Kuttig11Silke Stahlberg12Julia Strandmark13Angelika Schaffrath Rosario14Antje Gößwald15Andreas Nitsche16Osamah Hamouda17Christian Drosten18Victor Corman19Lothar H. Wieler20Lars Schaade21Thomas Lampert22Robert Koch Institute, Berlin Department of Epidemiology and Health MonitoringRobert Koch Institute, Berlin Department of Epidemiology and Health MonitoringRobert Koch Institute, Berlin Department of Epidemiology and Health MonitoringRobert Koch Institute, Berlin Department of Epidemiology and Health MonitoringRobert Koch Institute, Berlin Department of Epidemiology and Health MonitoringRobert Koch Institute, Berlin Department of Epidemiology and Health MonitoringRobert Koch Institute, Berlin Department of Infectious Disease EpidemiologyRobert Koch Institute, Berlin Department of Infectious Disease EpidemiologyRobert Koch Institute, Berlin Department of Epidemiology and Health MonitoringRobert Koch Institute, Berlin Department of Epidemiology and Health MonitoringRobert Koch Institute, Berlin Department of Epidemiology and Health MonitoringRobert Koch Institute, Berlin Department of Epidemiology and Health MonitoringRobert Koch Institute, Berlin Department of Epidemiology and Health MonitoringRobert Koch Institute, Berlin Department of Epidemiology and Health MonitoringRobert Koch Institute, Berlin Department of Epidemiology and Health MonitoringRobert Koch Institute, Berlin Department of Epidemiology and Health MonitoringRobert Koch Institute, Berlin Centre for Biological Threats and Special PathogensRobert Koch Institute, Berlin Department of Infectious Disease EpidemiologyCharité – Universitätsmedizin Berlin Institute of Virology, National Consultant Laboratory for CoronavirusesCharité – Universitätsmedizin Berlin Institute of Virology, National Consultant Laboratory for CoronavirusesRobert Koch Institute, Berlin Institute LeadershipRobert Koch Institute, Berlin Centre for Biological Threats and Special PathogensRobert Koch Institute, Berlin Department of Epidemiology and Health MonitoringAt a regional and local level, the COVID-19 pandemic has not spread out uniformly and some German municipalities have been particularly affected. The seroepidemiological data from these areas helps estimate the proportion of the population that has been infected with SARS-CoV-2 (seroprevalence), as well as the number of undetected infections and asymptomatic cases. In four municipalities which were especially affected, 2,000 participants will be tested for an active SARS-CoV-2 infection (oropharyngeal swab) or a past infection (blood specimen IgG antibody test). Participants will also be asked to fill out a short written questionnaire at study centres and complete a follow-up questionnaire either online or by telephone, including information on issues such as possible exposure, susceptability, symptoms and medical history. The CORONA-MONITORING lokal study will allow to determine the proportion of the population with SARS-CoV-2 antibodies in four particularly affected locations. This study will increase the accuracy of estimates regarding the scope of the epidemic, help determine risk and protective factors for an infection and therefore also identify especially exposed groups and, as such, it will be crucial towards planning of prevention measures.https://www.rki.de/EN/Content/Health_Monitoring/Health_Reporting/GBEDownloadsJ/JoHM_S5_2020_Study_protocol_CORONA_MONITORING_lokal.pdf?__blob=publicationFilesars-cov-2covid-19serological studycross-sectional studystudy protocolcorona hotspot
spellingShingle Claudia Santos-Hövener
Markus A. Busch
Carmen Koschollek
Martin Schlaud
Jens Hoebel
Robert Hoffmann
Hendrik Wilking
Sebastian Haller
Jennifer Allen
Jörg Wernitz
Hans Butschalowsky
Tim Kuttig
Silke Stahlberg
Julia Strandmark
Angelika Schaffrath Rosario
Antje Gößwald
Andreas Nitsche
Osamah Hamouda
Christian Drosten
Victor Corman
Lothar H. Wieler
Lars Schaade
Thomas Lampert
Seroepidemiological study on the spread of SARS-CoV-2 in populations in especially affected areas in Germany – Study protocol of the CORONA-MONITORING lokal study
Journal of Health Monitoring
sars-cov-2
covid-19
serological study
cross-sectional study
study protocol
corona hotspot
title Seroepidemiological study on the spread of SARS-CoV-2 in populations in especially affected areas in Germany – Study protocol of the CORONA-MONITORING lokal study
title_full Seroepidemiological study on the spread of SARS-CoV-2 in populations in especially affected areas in Germany – Study protocol of the CORONA-MONITORING lokal study
title_fullStr Seroepidemiological study on the spread of SARS-CoV-2 in populations in especially affected areas in Germany – Study protocol of the CORONA-MONITORING lokal study
title_full_unstemmed Seroepidemiological study on the spread of SARS-CoV-2 in populations in especially affected areas in Germany – Study protocol of the CORONA-MONITORING lokal study
title_short Seroepidemiological study on the spread of SARS-CoV-2 in populations in especially affected areas in Germany – Study protocol of the CORONA-MONITORING lokal study
title_sort seroepidemiological study on the spread of sars cov 2 in populations in especially affected areas in germany study protocol of the corona monitoring lokal study
topic sars-cov-2
covid-19
serological study
cross-sectional study
study protocol
corona hotspot
url https://www.rki.de/EN/Content/Health_Monitoring/Health_Reporting/GBEDownloadsJ/JoHM_S5_2020_Study_protocol_CORONA_MONITORING_lokal.pdf?__blob=publicationFile
work_keys_str_mv AT claudiasantoshovener seroepidemiologicalstudyonthespreadofsarscov2inpopulationsinespeciallyaffectedareasingermanystudyprotocolofthecoronamonitoringlokalstudy
AT markusabusch seroepidemiologicalstudyonthespreadofsarscov2inpopulationsinespeciallyaffectedareasingermanystudyprotocolofthecoronamonitoringlokalstudy
AT carmenkoschollek seroepidemiologicalstudyonthespreadofsarscov2inpopulationsinespeciallyaffectedareasingermanystudyprotocolofthecoronamonitoringlokalstudy
AT martinschlaud seroepidemiologicalstudyonthespreadofsarscov2inpopulationsinespeciallyaffectedareasingermanystudyprotocolofthecoronamonitoringlokalstudy
AT jenshoebel seroepidemiologicalstudyonthespreadofsarscov2inpopulationsinespeciallyaffectedareasingermanystudyprotocolofthecoronamonitoringlokalstudy
AT roberthoffmann seroepidemiologicalstudyonthespreadofsarscov2inpopulationsinespeciallyaffectedareasingermanystudyprotocolofthecoronamonitoringlokalstudy
AT hendrikwilking seroepidemiologicalstudyonthespreadofsarscov2inpopulationsinespeciallyaffectedareasingermanystudyprotocolofthecoronamonitoringlokalstudy
AT sebastianhaller seroepidemiologicalstudyonthespreadofsarscov2inpopulationsinespeciallyaffectedareasingermanystudyprotocolofthecoronamonitoringlokalstudy
AT jenniferallen seroepidemiologicalstudyonthespreadofsarscov2inpopulationsinespeciallyaffectedareasingermanystudyprotocolofthecoronamonitoringlokalstudy
AT jorgwernitz seroepidemiologicalstudyonthespreadofsarscov2inpopulationsinespeciallyaffectedareasingermanystudyprotocolofthecoronamonitoringlokalstudy
AT hansbutschalowsky seroepidemiologicalstudyonthespreadofsarscov2inpopulationsinespeciallyaffectedareasingermanystudyprotocolofthecoronamonitoringlokalstudy
AT timkuttig seroepidemiologicalstudyonthespreadofsarscov2inpopulationsinespeciallyaffectedareasingermanystudyprotocolofthecoronamonitoringlokalstudy
AT silkestahlberg seroepidemiologicalstudyonthespreadofsarscov2inpopulationsinespeciallyaffectedareasingermanystudyprotocolofthecoronamonitoringlokalstudy
AT juliastrandmark seroepidemiologicalstudyonthespreadofsarscov2inpopulationsinespeciallyaffectedareasingermanystudyprotocolofthecoronamonitoringlokalstudy
AT angelikaschaffrathrosario seroepidemiologicalstudyonthespreadofsarscov2inpopulationsinespeciallyaffectedareasingermanystudyprotocolofthecoronamonitoringlokalstudy
AT antjegoßwald seroepidemiologicalstudyonthespreadofsarscov2inpopulationsinespeciallyaffectedareasingermanystudyprotocolofthecoronamonitoringlokalstudy
AT andreasnitsche seroepidemiologicalstudyonthespreadofsarscov2inpopulationsinespeciallyaffectedareasingermanystudyprotocolofthecoronamonitoringlokalstudy
AT osamahhamouda seroepidemiologicalstudyonthespreadofsarscov2inpopulationsinespeciallyaffectedareasingermanystudyprotocolofthecoronamonitoringlokalstudy
AT christiandrosten seroepidemiologicalstudyonthespreadofsarscov2inpopulationsinespeciallyaffectedareasingermanystudyprotocolofthecoronamonitoringlokalstudy
AT victorcorman seroepidemiologicalstudyonthespreadofsarscov2inpopulationsinespeciallyaffectedareasingermanystudyprotocolofthecoronamonitoringlokalstudy
AT lotharhwieler seroepidemiologicalstudyonthespreadofsarscov2inpopulationsinespeciallyaffectedareasingermanystudyprotocolofthecoronamonitoringlokalstudy
AT larsschaade seroepidemiologicalstudyonthespreadofsarscov2inpopulationsinespeciallyaffectedareasingermanystudyprotocolofthecoronamonitoringlokalstudy
AT thomaslampert seroepidemiologicalstudyonthespreadofsarscov2inpopulationsinespeciallyaffectedareasingermanystudyprotocolofthecoronamonitoringlokalstudy