Research progress on effect and mechanism of diesel exhaust particles on asthma

As a source of traffic-related air pollution, diesel particulate matter (DPM) associate with a variety of lung-related diseases, but there is no systematic review of the relationship between DPM and the development and progression of asthma. This article reviewed the relationship between DPM and ast...

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Main Authors: Chaohui MU, Qinghai LI, Xinjuan YU, Yize YIN, Wei HAN
Format: Article
Language:English
Published: Editorial Committee of Journal of Environmental and Occupational Medicine 2023-05-01
Series:环境与职业医学
Subjects:
Online Access:http://www.jeom.org/article/cn/10.11836/JEOM22475
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author Chaohui MU
Qinghai LI
Xinjuan YU
Yize YIN
Wei HAN
author_facet Chaohui MU
Qinghai LI
Xinjuan YU
Yize YIN
Wei HAN
author_sort Chaohui MU
collection DOAJ
description As a source of traffic-related air pollution, diesel particulate matter (DPM) associate with a variety of lung-related diseases, but there is no systematic review of the relationship between DPM and the development and progression of asthma. This article reviewed the relationship between DPM and asthma, the effect and mechanism of DPM on airway inflammation and remodeling in asthma, and illustrated that DPM exposure may participate in airway inflammation and remodeling through oxidative stress, immune regulation and regulation of lung and intestinal microecology, so as to promote the development and progression of asthma.
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spelling doaj.art-5f9b50b4bd8f405484502fb37626c7e52023-05-29T03:03:54ZengEditorial Committee of Journal of Environmental and Occupational Medicine环境与职业医学2095-99822023-05-0140552452810.11836/JEOM2247522475Research progress on effect and mechanism of diesel exhaust particles on asthmaChaohui MU0Qinghai LI1Xinjuan YU2Yize YIN3Wei HAN4Department of Respiratory and Critical Care Medicine, Qingdao University Affiliated Qingdao Municipal Hospital, Qingdao, Shandong 266071, ChinaDepartment of Respiratory and Critical Care Medicine, Qingdao University Affiliated Qingdao Municipal Hospital, Qingdao, Shandong 266071, ChinaDepartment of Respiratory and Critical Care Medicine, Qingdao University Affiliated Qingdao Municipal Hospital, Qingdao, Shandong 266071, ChinaSchool of Public Health, Qingdao University, Qingdao, Shandong 266071, ChinaDepartment of Respiratory and Critical Care Medicine, Qingdao University Affiliated Qingdao Municipal Hospital, Qingdao, Shandong 266071, ChinaAs a source of traffic-related air pollution, diesel particulate matter (DPM) associate with a variety of lung-related diseases, but there is no systematic review of the relationship between DPM and the development and progression of asthma. This article reviewed the relationship between DPM and asthma, the effect and mechanism of DPM on airway inflammation and remodeling in asthma, and illustrated that DPM exposure may participate in airway inflammation and remodeling through oxidative stress, immune regulation and regulation of lung and intestinal microecology, so as to promote the development and progression of asthma.http://www.jeom.org/article/cn/10.11836/JEOM22475diesel exhaust particlebronchial asthmaoxidative stressairway inflammationairway remodeling
spellingShingle Chaohui MU
Qinghai LI
Xinjuan YU
Yize YIN
Wei HAN
Research progress on effect and mechanism of diesel exhaust particles on asthma
环境与职业医学
diesel exhaust particle
bronchial asthma
oxidative stress
airway inflammation
airway remodeling
title Research progress on effect and mechanism of diesel exhaust particles on asthma
title_full Research progress on effect and mechanism of diesel exhaust particles on asthma
title_fullStr Research progress on effect and mechanism of diesel exhaust particles on asthma
title_full_unstemmed Research progress on effect and mechanism of diesel exhaust particles on asthma
title_short Research progress on effect and mechanism of diesel exhaust particles on asthma
title_sort research progress on effect and mechanism of diesel exhaust particles on asthma
topic diesel exhaust particle
bronchial asthma
oxidative stress
airway inflammation
airway remodeling
url http://www.jeom.org/article/cn/10.11836/JEOM22475
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AT yizeyin researchprogressoneffectandmechanismofdieselexhaustparticlesonasthma
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