Research Advances on Swine Acute Diarrhea Syndrome Coronavirus
Swine acute diarrhea syndrome coronavirus (SADS-CoV) is a virulent pathogen that causes acute diarrhea in piglets. The virus was first discovered in Guangdong Province, China, in 2017 and has since emerged in Jiangxi, Fujian, and Guangxi Provinces. The outbreak exhibited a localized and sporadic pat...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2024-01-01
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| Series: | Animals |
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| Online Access: | https://www.mdpi.com/2076-2615/14/3/448 |
| _version_ | 1797319071430082560 |
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| author | Chuancheng Liu Weili Huang Xinyan He Zhihua Feng Qi Chen |
| author_facet | Chuancheng Liu Weili Huang Xinyan He Zhihua Feng Qi Chen |
| author_sort | Chuancheng Liu |
| collection | DOAJ |
| description | Swine acute diarrhea syndrome coronavirus (SADS-CoV) is a virulent pathogen that causes acute diarrhea in piglets. The virus was first discovered in Guangdong Province, China, in 2017 and has since emerged in Jiangxi, Fujian, and Guangxi Provinces. The outbreak exhibited a localized and sporadic pattern, with no discernable temporal continuity. The virus can infect human progenitor cells and demonstrates considerable potential for cross-species transmission, representing a potential risk for zoonotic transmission. Therefore, continuous surveillance of and comprehensive research on SADS-CoV are imperative. This review provides an overview of the temporal and evolutionary features of SADS-CoV outbreaks, focusing on the structural characteristics of the virus, which serve as the basis for discussing its potential for interspecies transmission. Additionally, the review summarizes virus–host interactions, including the effects on host cells, as well as apoptotic and autophagic behaviors, and discusses prevention and treatment modalities for this viral infection. |
| first_indexed | 2024-03-08T04:01:34Z |
| format | Article |
| id | doaj.art-5f9f120975a94bd08f09c4bb180850b6 |
| institution | Directory Open Access Journal |
| issn | 2076-2615 |
| language | English |
| last_indexed | 2024-03-08T04:01:34Z |
| publishDate | 2024-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Animals |
| spelling | doaj.art-5f9f120975a94bd08f09c4bb180850b62024-02-09T15:06:43ZengMDPI AGAnimals2076-26152024-01-0114344810.3390/ani14030448Research Advances on Swine Acute Diarrhea Syndrome CoronavirusChuancheng Liu0Weili Huang1Xinyan He2Zhihua Feng3Qi Chen4College of Life Science, Fujian Normal University, Fuzhou 350117, ChinaCollege of Life Science, Fujian Normal University, Fuzhou 350117, ChinaCollege of Life Science, Fujian Normal University, Fuzhou 350117, ChinaCollege of Life Science, Fujian Normal University, Fuzhou 350117, ChinaCollege of Life Science, Fujian Normal University, Fuzhou 350117, ChinaSwine acute diarrhea syndrome coronavirus (SADS-CoV) is a virulent pathogen that causes acute diarrhea in piglets. The virus was first discovered in Guangdong Province, China, in 2017 and has since emerged in Jiangxi, Fujian, and Guangxi Provinces. The outbreak exhibited a localized and sporadic pattern, with no discernable temporal continuity. The virus can infect human progenitor cells and demonstrates considerable potential for cross-species transmission, representing a potential risk for zoonotic transmission. Therefore, continuous surveillance of and comprehensive research on SADS-CoV are imperative. This review provides an overview of the temporal and evolutionary features of SADS-CoV outbreaks, focusing on the structural characteristics of the virus, which serve as the basis for discussing its potential for interspecies transmission. Additionally, the review summarizes virus–host interactions, including the effects on host cells, as well as apoptotic and autophagic behaviors, and discusses prevention and treatment modalities for this viral infection.https://www.mdpi.com/2076-2615/14/3/448swine acute diarrhea syndrome coronavirusSADS-CoVzoonosisvirus–host interactioncross-species transmission |
| spellingShingle | Chuancheng Liu Weili Huang Xinyan He Zhihua Feng Qi Chen Research Advances on Swine Acute Diarrhea Syndrome Coronavirus Animals swine acute diarrhea syndrome coronavirus SADS-CoV zoonosis virus–host interaction cross-species transmission |
| title | Research Advances on Swine Acute Diarrhea Syndrome Coronavirus |
| title_full | Research Advances on Swine Acute Diarrhea Syndrome Coronavirus |
| title_fullStr | Research Advances on Swine Acute Diarrhea Syndrome Coronavirus |
| title_full_unstemmed | Research Advances on Swine Acute Diarrhea Syndrome Coronavirus |
| title_short | Research Advances on Swine Acute Diarrhea Syndrome Coronavirus |
| title_sort | research advances on swine acute diarrhea syndrome coronavirus |
| topic | swine acute diarrhea syndrome coronavirus SADS-CoV zoonosis virus–host interaction cross-species transmission |
| url | https://www.mdpi.com/2076-2615/14/3/448 |
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