Sustainable Approach of Functional Biomaterials–Tissue Engineering for Skin Burn Treatment: A Comprehensive Review
Burns are a widespread global public health traumatic injury affecting many people worldwide. Non-fatal burn injuries are a leading cause of morbidity, resulting in prolonged hospitalization, disfigurement, and disability, often with resulting stigma and rejection. The treatment of burns is aimed at...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-05-01
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| Series: | Pharmaceuticals |
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| Online Access: | https://www.mdpi.com/1424-8247/16/5/701 |
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| author | Loai A. Elfawy Chiew Yong Ng Ibrahim N. Amirrah Zawani Mazlan Adzim Poh Yuen Wen Nur Izzah Md Fadilah Manira Maarof Yogeswaran Lokanathan Mh Busra Fauzi |
| author_facet | Loai A. Elfawy Chiew Yong Ng Ibrahim N. Amirrah Zawani Mazlan Adzim Poh Yuen Wen Nur Izzah Md Fadilah Manira Maarof Yogeswaran Lokanathan Mh Busra Fauzi |
| author_sort | Loai A. Elfawy |
| collection | DOAJ |
| description | Burns are a widespread global public health traumatic injury affecting many people worldwide. Non-fatal burn injuries are a leading cause of morbidity, resulting in prolonged hospitalization, disfigurement, and disability, often with resulting stigma and rejection. The treatment of burns is aimed at controlling pain, removing dead tissue, preventing infection, reducing scarring risk, and tissue regeneration. Traditional burn wound treatment methods include the use of synthetic materials such as petroleum-based ointments and plastic films. However, these materials can be associated with negative environmental impacts and may not be biocompatible with the human body. Tissue engineering has emerged as a promising approach to treating burns, and sustainable biomaterials have been developed as an alternative treatment option. Green biomaterials such as collagen, cellulose, chitosan, and others are biocompatible, biodegradable, environment-friendly, and cost-effective, which reduces the environmental impact of their production and disposal. They are effective in promoting wound healing and reducing the risk of infection and have other benefits such as reducing inflammation and promoting angiogenesis. This comprehensive review focuses on the use of multifunctional green biomaterials that have the potential to revolutionize the way we treat skin burns, promoting faster and more efficient healing while minimizing scarring and tissue damage. |
| first_indexed | 2024-03-11T03:25:25Z |
| format | Article |
| id | doaj.art-5f9f3b31ead543dca4f1d443cac5fe4a |
| institution | Directory Open Access Journal |
| issn | 1424-8247 |
| language | English |
| last_indexed | 2024-03-11T03:25:25Z |
| publishDate | 2023-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Pharmaceuticals |
| spelling | doaj.art-5f9f3b31ead543dca4f1d443cac5fe4a2023-11-18T02:48:40ZengMDPI AGPharmaceuticals1424-82472023-05-0116570110.3390/ph16050701Sustainable Approach of Functional Biomaterials–Tissue Engineering for Skin Burn Treatment: A Comprehensive ReviewLoai A. Elfawy0Chiew Yong Ng1Ibrahim N. Amirrah2Zawani Mazlan3Adzim Poh Yuen Wen4Nur Izzah Md Fadilah5Manira Maarof6Yogeswaran Lokanathan7Mh Busra Fauzi8Centre for Tissue Engineering and Regenerative Medicine, Faculty of Medicine, University Kebangsaan Malaysia, Kuala Lumpur 56000, MalaysiaCentre for Tissue Engineering and Regenerative Medicine, Faculty of Medicine, University Kebangsaan Malaysia, Kuala Lumpur 56000, MalaysiaCentre for Tissue Engineering and Regenerative Medicine, Faculty of Medicine, University Kebangsaan Malaysia, Kuala Lumpur 56000, MalaysiaCentre for Tissue Engineering and Regenerative Medicine, Faculty of Medicine, University Kebangsaan Malaysia, Kuala Lumpur 56000, MalaysiaCentre for Tissue Engineering and Regenerative Medicine, Faculty of Medicine, University Kebangsaan Malaysia, Kuala Lumpur 56000, MalaysiaCentre for Tissue Engineering and Regenerative Medicine, Faculty of Medicine, University Kebangsaan Malaysia, Kuala Lumpur 56000, MalaysiaCentre for Tissue Engineering and Regenerative Medicine, Faculty of Medicine, University Kebangsaan Malaysia, Kuala Lumpur 56000, MalaysiaCentre for Tissue Engineering and Regenerative Medicine, Faculty of Medicine, University Kebangsaan Malaysia, Kuala Lumpur 56000, MalaysiaCentre for Tissue Engineering and Regenerative Medicine, Faculty of Medicine, University Kebangsaan Malaysia, Kuala Lumpur 56000, MalaysiaBurns are a widespread global public health traumatic injury affecting many people worldwide. Non-fatal burn injuries are a leading cause of morbidity, resulting in prolonged hospitalization, disfigurement, and disability, often with resulting stigma and rejection. The treatment of burns is aimed at controlling pain, removing dead tissue, preventing infection, reducing scarring risk, and tissue regeneration. Traditional burn wound treatment methods include the use of synthetic materials such as petroleum-based ointments and plastic films. However, these materials can be associated with negative environmental impacts and may not be biocompatible with the human body. Tissue engineering has emerged as a promising approach to treating burns, and sustainable biomaterials have been developed as an alternative treatment option. Green biomaterials such as collagen, cellulose, chitosan, and others are biocompatible, biodegradable, environment-friendly, and cost-effective, which reduces the environmental impact of their production and disposal. They are effective in promoting wound healing and reducing the risk of infection and have other benefits such as reducing inflammation and promoting angiogenesis. This comprehensive review focuses on the use of multifunctional green biomaterials that have the potential to revolutionize the way we treat skin burns, promoting faster and more efficient healing while minimizing scarring and tissue damage.https://www.mdpi.com/1424-8247/16/5/701skin burnsustainable biomaterialsmultifunctional bioscaffoldscollagencellulosechitosan |
| spellingShingle | Loai A. Elfawy Chiew Yong Ng Ibrahim N. Amirrah Zawani Mazlan Adzim Poh Yuen Wen Nur Izzah Md Fadilah Manira Maarof Yogeswaran Lokanathan Mh Busra Fauzi Sustainable Approach of Functional Biomaterials–Tissue Engineering for Skin Burn Treatment: A Comprehensive Review Pharmaceuticals skin burn sustainable biomaterials multifunctional bioscaffolds collagen cellulose chitosan |
| title | Sustainable Approach of Functional Biomaterials–Tissue Engineering for Skin Burn Treatment: A Comprehensive Review |
| title_full | Sustainable Approach of Functional Biomaterials–Tissue Engineering for Skin Burn Treatment: A Comprehensive Review |
| title_fullStr | Sustainable Approach of Functional Biomaterials–Tissue Engineering for Skin Burn Treatment: A Comprehensive Review |
| title_full_unstemmed | Sustainable Approach of Functional Biomaterials–Tissue Engineering for Skin Burn Treatment: A Comprehensive Review |
| title_short | Sustainable Approach of Functional Biomaterials–Tissue Engineering for Skin Burn Treatment: A Comprehensive Review |
| title_sort | sustainable approach of functional biomaterials tissue engineering for skin burn treatment a comprehensive review |
| topic | skin burn sustainable biomaterials multifunctional bioscaffolds collagen cellulose chitosan |
| url | https://www.mdpi.com/1424-8247/16/5/701 |
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