Probing the Mechanism of Action of Cry41Aa on HepG2 through the Establishment of a Resistant Subline

Probing the Mechanism of Action of Cry41Aa on HepG2 through the Establishment of a Resistant Subline

Cry41Aa, also called parasporin-3, belongs to a group of toxins from the entomopathogenic bacterium <i>Bacillus thuringiensis</i> that show activity against human cancer cells. Cry41Aa exhibits preferential cytocidal activity towards HL-60 (human promyelocytic leukaemia cells) and HepG2...

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Bibliographic Details
Main Authors: Wided Souissi, Tweedie Alistair, Barbara Domanska, Eva Fortea, Michelle J. West, Jean-Louis Schwartz, Neil Crickmore
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Toxins
Subjects:
cry toxin
parasporin
HepG2
AQP9
Online Access:https://www.mdpi.com/2072-6651/14/5/319

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