Loss of GDE2 leads to complex behavioral changes including memory impairment

Loss of GDE2 leads to complex behavioral changes including memory impairment

Abstract Background Alzheimer’s disease (AD) and amyotrophic lateral sclerosis/frontotemporal dementia (ALS/FTD) are debilitating neurodegenerative diseases for which there are currently no cures. Familial cases with known genetic causes make up less than 10% of these diseases, and little is known a...

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Bibliographic Details
Main Authors: Daniel Daudelin, Anna Westerhaus, Nan Zhang, Erica Leyder, Alena Savonenko, Shanthini Sockanathan
Format: Article
Language:English
Published: BMC 2024-04-01
Series:Behavioral and Brain Functions
Subjects:
GDE2
Neurodegeneration
Disease
Behavior
Memory impairment
Hyperactivity
Online Access:https://doi.org/10.1186/s12993-024-00234-1

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