Mechanistic insights into synergy between nalidixic acid and tetracycline against clinical isolates of Acinetobacter baumannii and Escherichia coli
Gaurav et al. report a synergistic interaction between nalidixic acid and tetracycline against multi-drug resistant bacteria Acinetobacter baumannii and Escherichia coli. They find that this synergy does not work for clinical isolates susceptible to antibiotics, suggesting the potential application...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2021-05-01
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| Series: | Communications Biology |
| Online Access: | https://doi.org/10.1038/s42003-021-02074-5 |
| _version_ | 1818992695038705664 |
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| author | Amit Gaurav Varsha Gupta Sandeep K. Shrivastava Ranjana Pathania |
| author_facet | Amit Gaurav Varsha Gupta Sandeep K. Shrivastava Ranjana Pathania |
| author_sort | Amit Gaurav |
| collection | DOAJ |
| description | Gaurav et al. report a synergistic interaction between nalidixic acid and tetracycline against multi-drug resistant bacteria Acinetobacter baumannii and Escherichia coli. They find that this synergy does not work for clinical isolates susceptible to antibiotics, suggesting the potential application of nalidixic acid and tetracycline against the emergence of multi-drug resistant bacteria. |
| first_indexed | 2024-12-20T20:30:14Z |
| format | Article |
| id | doaj.art-5fa4ed4a3c9c4db28bbbc07074870b2a |
| institution | Directory Open Access Journal |
| issn | 2399-3642 |
| language | English |
| last_indexed | 2024-12-20T20:30:14Z |
| publishDate | 2021-05-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Communications Biology |
| spelling | doaj.art-5fa4ed4a3c9c4db28bbbc07074870b2a2022-12-21T19:27:22ZengNature PortfolioCommunications Biology2399-36422021-05-014111210.1038/s42003-021-02074-5Mechanistic insights into synergy between nalidixic acid and tetracycline against clinical isolates of Acinetobacter baumannii and Escherichia coliAmit Gaurav0Varsha Gupta1Sandeep K. Shrivastava2Ranjana Pathania3Department of Biotechnology, Indian Institute of Technology RoorkeeDepartment of Microbiology, Government Medical College and Hospital ChandigarhCentre for Innovation, Research and Development, Dr. B. Lal Clinical Laboratory Pvt LtdDepartment of Biotechnology, Indian Institute of Technology RoorkeeGaurav et al. report a synergistic interaction between nalidixic acid and tetracycline against multi-drug resistant bacteria Acinetobacter baumannii and Escherichia coli. They find that this synergy does not work for clinical isolates susceptible to antibiotics, suggesting the potential application of nalidixic acid and tetracycline against the emergence of multi-drug resistant bacteria.https://doi.org/10.1038/s42003-021-02074-5 |
| spellingShingle | Amit Gaurav Varsha Gupta Sandeep K. Shrivastava Ranjana Pathania Mechanistic insights into synergy between nalidixic acid and tetracycline against clinical isolates of Acinetobacter baumannii and Escherichia coli Communications Biology |
| title | Mechanistic insights into synergy between nalidixic acid and tetracycline against clinical isolates of Acinetobacter baumannii and Escherichia coli |
| title_full | Mechanistic insights into synergy between nalidixic acid and tetracycline against clinical isolates of Acinetobacter baumannii and Escherichia coli |
| title_fullStr | Mechanistic insights into synergy between nalidixic acid and tetracycline against clinical isolates of Acinetobacter baumannii and Escherichia coli |
| title_full_unstemmed | Mechanistic insights into synergy between nalidixic acid and tetracycline against clinical isolates of Acinetobacter baumannii and Escherichia coli |
| title_short | Mechanistic insights into synergy between nalidixic acid and tetracycline against clinical isolates of Acinetobacter baumannii and Escherichia coli |
| title_sort | mechanistic insights into synergy between nalidixic acid and tetracycline against clinical isolates of acinetobacter baumannii and escherichia coli |
| url | https://doi.org/10.1038/s42003-021-02074-5 |
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