Value of 18F-fluorodeoxyglucose positron emission tomography/computed tomography ın the diagnosis of carcinoma of unknown primary origin
<p><strong>Introduction:</strong> The incidence of carcinoma of unknown primary origin in oncologic patients is from 0,5 % to 7 % at the time of diagnosis with an overall 3-year and 5-year survival of 11 % and 6 %, respectively.</p><p><strong>Objective:</strong...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Universidad de Ciencias Médicas de La Habana
2019-11-01
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| Series: | Revista Habanera de Ciencias Médicas |
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| Online Access: | http://www.revhabanera.sld.cu/index.php/rhab/article/view/2435 |
| _version_ | 1818318001068310528 |
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| author | Claudia González Espinosa Juan Perfecto Oliva González Aldo Martínez Ramírez Joaquín González González Carlos Calderón Marín Frank Vázquez Luna Waldo Quesada Cepero |
| author_facet | Claudia González Espinosa Juan Perfecto Oliva González Aldo Martínez Ramírez Joaquín González González Carlos Calderón Marín Frank Vázquez Luna Waldo Quesada Cepero |
| author_sort | Claudia González Espinosa |
| collection | DOAJ |
| description | <p><strong>Introduction:</strong> The incidence of carcinoma of unknown primary origin in oncologic patients is from 0,5 % to 7 % at the time of diagnosis with an overall 3-year and 5-year survival of 11 % and 6 %, respectively.</p><p><strong>Objective:</strong> To assess the effectiveness of 18 F-FDG-PET/CT (18F-fluorodeoxyglucose posıtron emıssıon tomography) in the diagnosis of carcinoma of unknown primary origin (CUP). </p><p><strong>Material and Methods:</strong> F-FDG-PET/CT studies were conducted in patients with CUP in the search for primary tumor with negative previous conventional studies carried out from November, 2017 to June 2018. The final diagnosis was established by histological confirmation and/or clinical/radiological follow-up during 8 months. </p><strong>Results:</strong> A total of 44 patients were studied. There were evidences of suggestive CUP in 19 patients; 9 of them were histologically confirmed as true-positive and only 1 was a false-positive. Of the 23 patients with negative F-FDG-PET/CT studies for primary tumor, all of them continued with the diagnosis of CUP in spite of multiples diagnostic tests. <strong>Conclusions:</strong> The FDG-PET/CT technique allowed to identify 45,2 % of the primary tumors in this study, which demonstrates that it is very useful tool for the diagnosis of metastases of unknown origin. It is considered that F-FDG-PET/CT studies should be included earlier in the diagnostic algorithms in Cuba, which will allow to indicate subsequent complementary tests. |
| first_indexed | 2024-12-13T09:46:16Z |
| format | Article |
| id | doaj.art-5fa6050a86f14200b8ab1967e0472a14 |
| institution | Directory Open Access Journal |
| issn | 1729-519X |
| language | English |
| last_indexed | 2024-12-13T09:46:16Z |
| publishDate | 2019-11-01 |
| publisher | Universidad de Ciencias Médicas de La Habana |
| record_format | Article |
| series | Revista Habanera de Ciencias Médicas |
| spelling | doaj.art-5fa6050a86f14200b8ab1967e0472a142022-12-21T23:52:04ZengUniversidad de Ciencias Médicas de La HabanaRevista Habanera de Ciencias Médicas1729-519X2019-11-011868738851511Value of 18F-fluorodeoxyglucose positron emission tomography/computed tomography ın the diagnosis of carcinoma of unknown primary originClaudia González Espinosa0Juan Perfecto Oliva González1Aldo Martínez Ramírez2Joaquín González González3Carlos Calderón Marín4Frank Vázquez Luna5Waldo Quesada Cepero6Instituto Nacional de Oncología y Radiobiología. La Habana.Instituto Nacional de Oncología y Radiobiología; Universidad de Ciencias Médicas de La Habana. La Habana.Instituto Nacional de Oncología y Radiobiología; Universidad de Ciencias Médicas de La Habana. La Habana.Instituto Nacional de Oncología y Radiobiología; Universidad de Ciencias Médicas de La Habana. La Habana.Instituto Nacional de Oncología y Radiobiología. La Habana.Hospital General Docente “Dr. Enrique Cabrera”. La Habana.Instituto Nacional de Oncología y Radiobiología. La Habana.<p><strong>Introduction:</strong> The incidence of carcinoma of unknown primary origin in oncologic patients is from 0,5 % to 7 % at the time of diagnosis with an overall 3-year and 5-year survival of 11 % and 6 %, respectively.</p><p><strong>Objective:</strong> To assess the effectiveness of 18 F-FDG-PET/CT (18F-fluorodeoxyglucose posıtron emıssıon tomography) in the diagnosis of carcinoma of unknown primary origin (CUP). </p><p><strong>Material and Methods:</strong> F-FDG-PET/CT studies were conducted in patients with CUP in the search for primary tumor with negative previous conventional studies carried out from November, 2017 to June 2018. The final diagnosis was established by histological confirmation and/or clinical/radiological follow-up during 8 months. </p><strong>Results:</strong> A total of 44 patients were studied. There were evidences of suggestive CUP in 19 patients; 9 of them were histologically confirmed as true-positive and only 1 was a false-positive. Of the 23 patients with negative F-FDG-PET/CT studies for primary tumor, all of them continued with the diagnosis of CUP in spite of multiples diagnostic tests. <strong>Conclusions:</strong> The FDG-PET/CT technique allowed to identify 45,2 % of the primary tumors in this study, which demonstrates that it is very useful tool for the diagnosis of metastases of unknown origin. It is considered that F-FDG-PET/CT studies should be included earlier in the diagnostic algorithms in Cuba, which will allow to indicate subsequent complementary tests.http://www.revhabanera.sld.cu/index.php/rhab/article/view/2435tumor de origen desconocido, tod, pet/ct, pet-fdg, metástasis sin primario conocido. |
| spellingShingle | Claudia González Espinosa Juan Perfecto Oliva González Aldo Martínez Ramírez Joaquín González González Carlos Calderón Marín Frank Vázquez Luna Waldo Quesada Cepero Value of 18F-fluorodeoxyglucose positron emission tomography/computed tomography ın the diagnosis of carcinoma of unknown primary origin Revista Habanera de Ciencias Médicas tumor de origen desconocido, tod, pet/ct, pet-fdg, metástasis sin primario conocido. |
| title | Value of 18F-fluorodeoxyglucose positron emission tomography/computed tomography ın the diagnosis of carcinoma of unknown primary origin |
| title_full | Value of 18F-fluorodeoxyglucose positron emission tomography/computed tomography ın the diagnosis of carcinoma of unknown primary origin |
| title_fullStr | Value of 18F-fluorodeoxyglucose positron emission tomography/computed tomography ın the diagnosis of carcinoma of unknown primary origin |
| title_full_unstemmed | Value of 18F-fluorodeoxyglucose positron emission tomography/computed tomography ın the diagnosis of carcinoma of unknown primary origin |
| title_short | Value of 18F-fluorodeoxyglucose positron emission tomography/computed tomography ın the diagnosis of carcinoma of unknown primary origin |
| title_sort | value of 18f fluorodeoxyglucose positron emission tomography computed tomography in the diagnosis of carcinoma of unknown primary origin |
| topic | tumor de origen desconocido, tod, pet/ct, pet-fdg, metástasis sin primario conocido. |
| url | http://www.revhabanera.sld.cu/index.php/rhab/article/view/2435 |
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