Synthesis, and Antitumor Activity of Some N1-(Coumarin-7-yl) Amidrazones and Related Congeners

Synthesis, and Antitumor Activity of Some N1-(Coumarin-7-yl) Amidrazones and Related Congeners

A series of new N1-(coumarin-7-yl)amidrazones incorporating N-piperazines and related congeners were synthesized by reacting the hydrazonoyl chloride derived from 7-amino-4-methylcoumarin with the appropriate piperazines. The chemical structures of the newly prepared compounds were supported by elem...

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Bibliographic Details
Main Authors: Mohammad S. Mustafa, Mustafa M. El-Abadelah, Malek A. Zihlif, Randa G. Naffa, Mohammad S. Mubarak
Format: Article
Language:English
Published: MDPI AG 2011-05-01
Series:Molecules
Subjects:
7-aminocoumarins
N-(coumarin-7-yl)hydrazonoyl chloride
1-piperazinyl amidrazones
nitrileimine
antitumor activity
Online Access:http://www.mdpi.com/1420-3049/16/5/4305/

Internet

http://www.mdpi.com/1420-3049/16/5/4305/

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