CCAAT/Enhancer-Binding Proteins in Fibrosis: Complex Roles Beyond Conventional Understanding

CCAAT/Enhancer-Binding Proteins in Fibrosis: Complex Roles Beyond Conventional Understanding

CCAAT/enhancer-binding proteins (C/EBPs) are a family of at least six identified transcription factors that contain a highly conserved basic leucine zipper domain and interact selectively with duplex DNA to regulate target gene expression. C/EBPs play important roles in various physiological process...

Full description

Bibliographic Details
Main Authors:	Lexun Wang, Jiaojiao Feng, Yanyue Deng, Qianqian Yang, Quxing Wei, Dewei Ye, Xianglu Rong, Jiao Guo
Format:	Article
Language:	English
Published:	American Association for the Advancement of Science (AAAS) 2022-01-01
Series:	Research
Online Access:	http://dx.doi.org/10.34133/2022/9891689

Similar Items

The markers to delineate different phenotypes of macrophages related to metabolic disorders
by: Quxing Wei, et al.
Published: (2023-02-01)

The function and regulation of CCAAT/enhancer binding protein ε
by: Shaowen Cheng, et al.
Published: (2023-01-01)

Role of the CCAAT-binding protein NFY in SCA17 pathogenesis.
by: Li-Ching Lee, et al.
Published: (2012-01-01)

Sterol Biosynthesis and Azole Tolerance Is Governed by the Opposing Actions of SrbA and the CCAAT Binding Complex.
by: Fabio Gsaller, et al.
Published: (2016-07-01)

Comprehensive Analysis of CCAAT/Enhancer Binding Protein Family in Ovarian Cancer
by: Jiahong Tan, et al.
Published: (2024-09-01)

CCAAT/enhancer binding protein β is dispensable for development of lung adenocarcinoma.
by: Yi Cai, et al.
Published: (2015-01-01)

Transcriptional control of CCAAT/enhancer binding protein zeta gene in chicken adipose tissue
by: Lingyu Gao, et al.
Published: (2024-04-01)

Detrimental role for CCAAT/enhancer binding protein δ in blood-borne brain infection
by: JanWillem Duitman, et al.
Published: (2016-11-01)

CCAAT/Enhancer-binding Protein-mediated Inhibition of HTLV-1 Viral Gene Expression
by: Wigdahl Brian, et al.
Published: (2005-12-01)

The CCAAT/Enhancer Binding Protein Beta (cebpb) is essential for the development of enveloping layer (EVL) in zebrafish
by: Xin Zhang, et al.
Published: (2023-05-01)

CCAAT-enhancer binding protein-β expression and elevation in Alzheimer's disease and microglial cell cultures.
by: Ron Strohmeyer, et al.
Published: (2014-01-01)

Expression of CCAAT/Enhancer Binding Protein Beta in Muscle Satellite Cells Inhibits Myogenesis in Cancer Cachexia.
by: François Marchildon, et al.
Published: (2015-01-01)

Cyclic AMP responsive element binding proteins are involved in 'emergency' granulopoiesis through the upregulation of CCAAT/enhancer binding protein β.
by: Hideyo Hirai, et al.
Published: (2013-01-01)

Deficiency of CCAAT/enhancer binding protein family DNA binding prevents malignant conversion of adenoma to carcinoma in NNK-induced lung carcinogenesis in the mouse
by: Kimura Shioko, et al.
Published: (2012-12-01)

Non-Tumor CCAAT/Enhancer-Binding Protein Delta Potentiates Tumor Cell Extravasation and Pancreatic Cancer Metastasis Formation
by: JanWillem Duitman, et al.
Published: (2021-07-01)

The gene signature in CCAAT-enhancer-binding protein α dysfunctional acute myeloid leukemia predicts responsiveness to histone deacetylase inhibitors
by: Adam Liss, et al.
Published: (2014-04-01)

Ablation of CCAAT/Enhancer-Binding Protein Delta (C/EBPD): Increased Plaque Burden in a Murine Alzheimer's Disease Model.
by: Manuel Lutzenberger, et al.
Published: (2015-01-01)

Joint Analysis of CCAAT/Enhancer-Binding Protein Beta and Interleukin 1 Beta in the Treatment and Prognosis of Diffuse Large B-Cell Lymphoma
by: Hongmin Wang, et al.
Published: (2024-10-01)

Deubiquitinase USP1 enhances CCAAT/enhancer-binding protein beta (C/EBPβ) stability and accelerates adipogenesis and lipid accumulation
by: Myung Sup Kim, et al.
Published: (2023-11-01)

Molecular basis of non-deletional HPFH in Thailand and identification of two novel mutations at the binding sites of CCAAT and GATA-1 transcription factors
by: Kritsada Singha, et al.
Published: (2023-07-01)

Role of nitric oxide and CCAAT/enhancer-binding protein transcription factor in statin-dependent induction of heme oxygenase-1 in mouse macrophages.
by: Charbel A Mouawad, et al.
Published: (2013-01-01)

CCAAT/enhancer-binding protein-α suppresses lung tumor development in mice through the p38α MAP kinase pathway.
by: Atsuyasu Sato, et al.
Published: (2013-01-01)

CCAAT/Enhancer-Binding Protein β Mediates Oxygen-Induced Retinal Neovascularization via Retinal Vascular Damage and Vascular Endothelial Growth Factor
by: Tingting Li, et al.
Published: (2020-01-01)

The CCAAT/enhancer-binding protein beta-2 isoform (CEBPβ-2) upregulates galectin-7 expression in human breast cancer cells.
by: Carole G Campion, et al.
Published: (2014-01-01)

Nuclear factor-Y (NF-Y) regulates transcription of mouse Dmrt7 gene by binding to tandem CCAAT boxes in its proximal promoter
by: Yu Hou, Xiang Zhou, Jie Liu, Jia Yuan, Hanhua Cheng, Rongjia Zhou
Published: (2010-01-01)

CCAAT/enhancer-binding protein delta regulates the stemness of glioma stem-like cells through activating PDGFA expression upon inflammatory stimulation
by: Shao-Ming Wang, et al.
Published: (2019-07-01)

Bigelovii A Protects against Lipopolysaccharide-Induced Acute Lung Injury by Blocking NF-κB and CCAAT/Enhancer-Binding Protein δ Pathways
by: Chunguang Yan, et al.
Published: (2016-01-01)

CCAAT/enhancer binding protein delta (C/EBPδ) demonstrates a dichotomous role in tumour initiation and promotion of epithelial carcinomaResearch in context
by: Ramlogan Sowamber, et al.
Published: (2019-06-01)

Concordant acute myeloblastic leukemia in monozygotic twins with germline and shared somatic mutations in the gene for CCAAT-enhancer-binding protein α with 13 years difference at onset
by: Maruša Debeljak, et al.
Published: (2013-07-01)

Correction: An NF-Y-Dependent Switch of Positive and Negative Histone Methyl Marks on CCAAT Promoters
Published: (2014-01-01)

Correction: An NF-Y-Dependent Switch of Positive and Negative Histone Methyl Marks on CCAAT Promoters.
Published: (2014-01-01)

The protease activated receptor 2 - CCAAT/enhancer-binding protein beta - SerpinB3 axis inhibition as a novel strategy for the treatment of non-alcoholic steatohepatitis
by: Gianmarco Villano, et al.
Published: (2024-03-01)

MicroRNA-24-3p alleviates cardiac fibrosis by suppressing cardiac fibroblasts mitophagy via downregulating PHB2
by: Yue Zhang, et al.
Published: (2022-03-01)

CCAAT enhancer binding protein delta activates vesicle associated membrane protein 3 transcription to enhance chemoresistance and extracellular PD-L1 expression in triple-negative breast cancer
by: Yan Zhao, et al.
Published: (2024-04-01)

Multiple transcription factors interact with the adenovirus-2 EII-late promoter: evidence for a novel CCAAT recognition factor.
by: Goding, C, et al.
Published: (1987)

Beyond conventional therapies: MSCs in the battle against nerve injury
by: Shuo Song, et al.
Published: (2025-03-01)

A neglected complication of COVID-19: liver injury
by: Tian LAN, et al.
Published: (2021-03-01)

Differential effects of sumoylation on the activities of CCAAT enhancer binding protein alpha (C/EBPa) p42 versus p30 may contribute in part, to aberrant C/EBPa activity in acute leukemias
by: William Hankey, et al.
Published: (2011-05-01)

Beyond the limits of conventional Stark deceleration
by: David Reens, et al.
Published: (2020-07-01)

Effect of high glucose on the gene expression profiling in cardiac fibroblasts from rats at different ages
by: Quqian Mo, et al.
Published: (2025-03-01)