Induction of Multidrug Tolerance in Plasmodium falciparum by Extended Artemisinin Pressure

Induction of Multidrug Tolerance in Plasmodium falciparum by Extended Artemisinin Pressure

Plasmodium falciparum resistance to artemisinin derivatives in Southeast Asia threatens global malaria control strategies. Whether delayed parasite clearance, which exposes larger parasite numbers to artemisinins for longer times, selects higher-grade resistance remains unexplored. We investigated w...

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Bibliographic Details
Main Authors: Sandie Ménard, Tanila Ben Haddou, Arba Pramundita Ramadani, Frédéric Ariey, Xavier Iriart, Johann Beghain, Christiane Bouchier, Benoit Witkowski, Antoine Berry, Odile Mercereau-Puijalon, Françoise Benoit-Vical
Format: Article
Language:English
Published: Centers for Disease Control and Prevention 2015-10-01
Series:Emerging Infectious Diseases
Subjects:
artemisinin
Plasmodium falciparum
parasites
multidrug tolerance
drug pressure
atovaquone
Online Access:https://wwwnc.cdc.gov/eid/article/21/10/15-0682_article

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