Four-gene signature predicting overall survival and immune infiltration in hepatocellular carcinoma by bioinformatics analysis with RT‒qPCR validation

Four-gene signature predicting overall survival and immune infiltration in hepatocellular carcinoma by bioinformatics analysis with RT‒qPCR validation

Abstract Background Hepatocellular carcinoma (HCC) is one of the most lethal cancers, with a poor prognosis. Prognostic biomarkers for HCC patients are urgently needed. We aimed to establish a nomogram prediction system that combines a gene signature to predict HCC prognosis. Methods Differentially...

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Bibliographic Details
Main Authors: Renguo Guan, Jingwen Zou, Jie Mei, Min Deng, Rongping Guo
Format: Article
Language:English
Published: BMC 2022-07-01
Series:BMC Cancer
Subjects:
Hepatocellular carcinoma
Signature
Nomogram
Prognosis
Immune infiltration
Online Access:https://doi.org/10.1186/s12885-022-09934-1

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