CLINICAL EFFICACY OF LOOP DIURETIC TORASEMIDE IN TREATMENT OF PATIENTS WITH CHRONIC HEART FAILURE. RESULTS OF KAZAKHSTAN MULTICENTER STUDY "POET"

Aim. To study the efficacy of loop diuretic torasemide compared with furosemide consisting of combination therapy in patients with chronic heart failure (CHF).Material and methods. Inpatient and outpatient patients (n=136; 80 men and 56 women) with CHF class 2-3 (NYHA) living in different regions of...

Full description

Bibliographic Details
Main Authors: S. F. Berkinbaev, G. A. Dzhunusbekova, A. K. Isabekova
Format: Article
Language:English
Published: Столичная издательская компания 2015-09-01
Series:Рациональная фармакотерапия в кардиологии
Subjects:
Online Access:https://www.rpcardio.online/jour/article/view/207
_version_ 1797232451097985024
author S. F. Berkinbaev
G. A. Dzhunusbekova
A. K. Isabekova
author_facet S. F. Berkinbaev
G. A. Dzhunusbekova
A. K. Isabekova
author_sort S. F. Berkinbaev
collection DOAJ
description Aim. To study the efficacy of loop diuretic torasemide compared with furosemide consisting of combination therapy in patients with chronic heart failure (CHF).Material and methods. Inpatient and outpatient patients (n=136; 80 men and 56 women) with CHF class 2-3 (NYHA) living in different regions of Kazakhstan were included into the study.Results. More pronounced decrease in edema syndrome, significant decrease in the rate of maladaptive myocardial remodeling, increase in systolic function by 8.2%, improving quality of life by 30.1% took place during combination therapy including loop diuretic torasemide compared with furosemide.Conclusion. The loop diuretic torasemide consisting of combination therapy has a positive effect on myocardial remodeling and improves quality of life in patients with CHF class 2-3 (NYHA).
first_indexed 2024-03-08T14:05:54Z
format Article
id doaj.art-5fb4a563580d4c9b9a4f1efb6cb62861
institution Directory Open Access Journal
issn 1819-6446
2225-3653
language English
last_indexed 2024-04-24T16:00:29Z
publishDate 2015-09-01
publisher Столичная издательская компания
record_format Article
series Рациональная фармакотерапия в кардиологии
spelling doaj.art-5fb4a563580d4c9b9a4f1efb6cb628612024-04-01T07:43:23ZengСтоличная издательская компанияРациональная фармакотерапия в кардиологии1819-64462225-36532015-09-0110549549910.20996/1819-6446-2014-10-5-495-499207CLINICAL EFFICACY OF LOOP DIURETIC TORASEMIDE IN TREATMENT OF PATIENTS WITH CHRONIC HEART FAILURE. RESULTS OF KAZAKHSTAN MULTICENTER STUDY "POET"S. F. Berkinbaev0G. A. Dzhunusbekova1A. K. Isabekova2Institute of Cardiology and Internal DiseasesInstitute of Cardiology and Internal DiseasesInstitute of Cardiology and Internal DiseasesAim. To study the efficacy of loop diuretic torasemide compared with furosemide consisting of combination therapy in patients with chronic heart failure (CHF).Material and methods. Inpatient and outpatient patients (n=136; 80 men and 56 women) with CHF class 2-3 (NYHA) living in different regions of Kazakhstan were included into the study.Results. More pronounced decrease in edema syndrome, significant decrease in the rate of maladaptive myocardial remodeling, increase in systolic function by 8.2%, improving quality of life by 30.1% took place during combination therapy including loop diuretic torasemide compared with furosemide.Conclusion. The loop diuretic torasemide consisting of combination therapy has a positive effect on myocardial remodeling and improves quality of life in patients with CHF class 2-3 (NYHA).https://www.rpcardio.online/jour/article/view/207chronic heart failuremaladaptive heart remodelingtorasemidequality of life
spellingShingle S. F. Berkinbaev
G. A. Dzhunusbekova
A. K. Isabekova
CLINICAL EFFICACY OF LOOP DIURETIC TORASEMIDE IN TREATMENT OF PATIENTS WITH CHRONIC HEART FAILURE. RESULTS OF KAZAKHSTAN MULTICENTER STUDY "POET"
Рациональная фармакотерапия в кардиологии
chronic heart failure
maladaptive heart remodeling
torasemide
quality of life
title CLINICAL EFFICACY OF LOOP DIURETIC TORASEMIDE IN TREATMENT OF PATIENTS WITH CHRONIC HEART FAILURE. RESULTS OF KAZAKHSTAN MULTICENTER STUDY "POET"
title_full CLINICAL EFFICACY OF LOOP DIURETIC TORASEMIDE IN TREATMENT OF PATIENTS WITH CHRONIC HEART FAILURE. RESULTS OF KAZAKHSTAN MULTICENTER STUDY "POET"
title_fullStr CLINICAL EFFICACY OF LOOP DIURETIC TORASEMIDE IN TREATMENT OF PATIENTS WITH CHRONIC HEART FAILURE. RESULTS OF KAZAKHSTAN MULTICENTER STUDY "POET"
title_full_unstemmed CLINICAL EFFICACY OF LOOP DIURETIC TORASEMIDE IN TREATMENT OF PATIENTS WITH CHRONIC HEART FAILURE. RESULTS OF KAZAKHSTAN MULTICENTER STUDY "POET"
title_short CLINICAL EFFICACY OF LOOP DIURETIC TORASEMIDE IN TREATMENT OF PATIENTS WITH CHRONIC HEART FAILURE. RESULTS OF KAZAKHSTAN MULTICENTER STUDY "POET"
title_sort clinical efficacy of loop diuretic torasemide in treatment of patients with chronic heart failure results of kazakhstan multicenter study poet
topic chronic heart failure
maladaptive heart remodeling
torasemide
quality of life
url https://www.rpcardio.online/jour/article/view/207
work_keys_str_mv AT sfberkinbaev clinicalefficacyofloopdiuretictorasemideintreatmentofpatientswithchronicheartfailureresultsofkazakhstanmulticenterstudypoet
AT gadzhunusbekova clinicalefficacyofloopdiuretictorasemideintreatmentofpatientswithchronicheartfailureresultsofkazakhstanmulticenterstudypoet
AT akisabekova clinicalefficacyofloopdiuretictorasemideintreatmentofpatientswithchronicheartfailureresultsofkazakhstanmulticenterstudypoet