SERUM MAGNESIUM AND SEVERITY OF DIABETIC RETINOPATHY

ABSTRACT Background: Diabetic retinopathy is the most frequent cause of new cases of blindness among adults aged 20–74 years. Magnesium deficiency is a possible metabolic factor involved in the pathogenesis of diabetic micro - and macro - vascular complications. Aim: To assess magnesium level in rel...

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Main Authors: Nazar Haddad, Salah Zuhair
Format: Article
Language:English
Published: University of Basrah 2010-06-01
Series:The Medical Journal of Basrah University
Online Access:https://mjbu.uobasrah.edu.iq/article_49460_66b26a695ce326f97789bd715e5c3065.pdf
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author Nazar Haddad
Salah Zuhair
author_facet Nazar Haddad
Salah Zuhair
author_sort Nazar Haddad
collection DOAJ
description ABSTRACT Background: Diabetic retinopathy is the most frequent cause of new cases of blindness among adults aged 20–74 years. Magnesium deficiency is a possible metabolic factor involved in the pathogenesis of diabetic micro - and macro - vascular complications. Aim: To assess magnesium level in relation to the stages of diabetic retinopathy. Methods: The study enrolled 136 diabetic patients consulting Ophthalmology Outpatient Department. The ophthalmologist assigned the patients into 5 categories; background, preproliferative, proliferative, advanced and maculopathy. Serum magnesium, random blood glucose and glycated hemoglobin were determined. Results: Among the 136 patients with diabetes mellitus, 94 patients had diabetic retinopathy and 42 had no retinopathy. There is a significant statistical differences (P-value <0.05) between diabetic retinopathy and control groups in serum magnesium, random blood glucose, glycated hemoglobin and duration of diabetes. It had been found that serum magnesium remained statistically significant among the groups of patients with different stages of retinopathy. Patients with maculopathy had the lowest value for the serum magnesium level (1.35 mg/dl) Conclusions: Serum magnesium level decreased in patients with diabetic retinopathy with lowest level being observed in patients with advanced retinopathy and maculopathy.
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spelling doaj.art-5fbab895824a4fa3bc7d18c61f787b1b2022-12-21T18:35:16ZengUniversity of BasrahThe Medical Journal of Basrah University0253-07592413-44142010-06-01281363910.33762/mjbu.2010.4946049460SERUM MAGNESIUM AND SEVERITY OF DIABETIC RETINOPATHYNazar Haddad0Salah ZuhairThe University of Basrah, College of Medicine, Department of BiochemistryABSTRACT Background: Diabetic retinopathy is the most frequent cause of new cases of blindness among adults aged 20–74 years. Magnesium deficiency is a possible metabolic factor involved in the pathogenesis of diabetic micro - and macro - vascular complications. Aim: To assess magnesium level in relation to the stages of diabetic retinopathy. Methods: The study enrolled 136 diabetic patients consulting Ophthalmology Outpatient Department. The ophthalmologist assigned the patients into 5 categories; background, preproliferative, proliferative, advanced and maculopathy. Serum magnesium, random blood glucose and glycated hemoglobin were determined. Results: Among the 136 patients with diabetes mellitus, 94 patients had diabetic retinopathy and 42 had no retinopathy. There is a significant statistical differences (P-value <0.05) between diabetic retinopathy and control groups in serum magnesium, random blood glucose, glycated hemoglobin and duration of diabetes. It had been found that serum magnesium remained statistically significant among the groups of patients with different stages of retinopathy. Patients with maculopathy had the lowest value for the serum magnesium level (1.35 mg/dl) Conclusions: Serum magnesium level decreased in patients with diabetic retinopathy with lowest level being observed in patients with advanced retinopathy and maculopathy.https://mjbu.uobasrah.edu.iq/article_49460_66b26a695ce326f97789bd715e5c3065.pdf
spellingShingle Nazar Haddad
Salah Zuhair
SERUM MAGNESIUM AND SEVERITY OF DIABETIC RETINOPATHY
The Medical Journal of Basrah University
title SERUM MAGNESIUM AND SEVERITY OF DIABETIC RETINOPATHY
title_full SERUM MAGNESIUM AND SEVERITY OF DIABETIC RETINOPATHY
title_fullStr SERUM MAGNESIUM AND SEVERITY OF DIABETIC RETINOPATHY
title_full_unstemmed SERUM MAGNESIUM AND SEVERITY OF DIABETIC RETINOPATHY
title_short SERUM MAGNESIUM AND SEVERITY OF DIABETIC RETINOPATHY
title_sort serum magnesium and severity of diabetic retinopathy
url https://mjbu.uobasrah.edu.iq/article_49460_66b26a695ce326f97789bd715e5c3065.pdf
work_keys_str_mv AT nazarhaddad serummagnesiumandseverityofdiabeticretinopathy
AT salahzuhair serummagnesiumandseverityofdiabeticretinopathy