INDIRECT MEASURES OF NEUROPROTECTION ARE PARAMETERS TO AVOID: EXAMPLES FROM RESEARCH ON NEONATAL RAT HYPOXIA-ISCHEMIA

INDIRECT MEASURES OF NEUROPROTECTION ARE PARAMETERS TO AVOID: EXAMPLES FROM RESEARCH ON NEONATAL RAT HYPOXIA-ISCHEMIA

The use of indirect measures of neuronal injury or neuroprotection, such as brain weight or the neuronal density of neurons, can lead to misinterpretations of biological processes. The use of modern stereological methods to directly measure the absolute number of surviving neurons generally yields m...

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Bibliographic Details
Main Author: Dorothy E Oorschot
Format: Article
Language:English
Published: Slovenian Society for Stereology and Quantitative Image Analysis 2011-03-01
Series:Image Analysis and Stereology
Subjects:
absolute neuronal number
brain weight
Cavalieri’s method
neuronal density
optical disector
stereology
Online Access:http://www.ias-iss.org/ojs/IAS/article/view/18

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