Proteogenomic landscape and clinical characterization of GH-producing pituitary adenomas/somatotroph pituitary neuroendocrine tumors
The genetic alterations, protein expressions, and clinical characteristics of growth hormone-producing pituitary adenomas/somatotroph pituitary neuroendocrine tumors are integrated to detect molecules associated with acromegaly characteristics.
| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2022-11-01
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| Series: | Communications Biology |
| Online Access: | https://doi.org/10.1038/s42003-022-04272-1 |
| _version_ | 1811304421732122624 |
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| author | Azusa Yamato Hidekazu Nagano Yue Gao Tatsuma Matsuda Naoko Hashimoto Akitoshi Nakayama Kazuyuki Yamagata Masataka Yokoyama Yingbo Gong Xiaoyan Shi Siti Nurul Zhahara Takashi Kono Yuki Taki Naoto Furuki Motoi Nishimura Kentaro Horiguchi Yasuo Iwadate Masaki Fukuyo Bahityar Rahmutulla Atsushi Kaneda Yoshinori Hasegawa Yusuke Kawashima Osamu Ohara Tetsuo Ishikawa Eiryo Kawakami Yasuhiro Nakamura Naoko Inoshita Shozo Yamada Noriaki Fukuhara Hiroshi Nishioka Tomoaki Tanaka |
| author_facet | Azusa Yamato Hidekazu Nagano Yue Gao Tatsuma Matsuda Naoko Hashimoto Akitoshi Nakayama Kazuyuki Yamagata Masataka Yokoyama Yingbo Gong Xiaoyan Shi Siti Nurul Zhahara Takashi Kono Yuki Taki Naoto Furuki Motoi Nishimura Kentaro Horiguchi Yasuo Iwadate Masaki Fukuyo Bahityar Rahmutulla Atsushi Kaneda Yoshinori Hasegawa Yusuke Kawashima Osamu Ohara Tetsuo Ishikawa Eiryo Kawakami Yasuhiro Nakamura Naoko Inoshita Shozo Yamada Noriaki Fukuhara Hiroshi Nishioka Tomoaki Tanaka |
| author_sort | Azusa Yamato |
| collection | DOAJ |
| description | The genetic alterations, protein expressions, and clinical characteristics of growth hormone-producing pituitary adenomas/somatotroph pituitary neuroendocrine tumors are integrated to detect molecules associated with acromegaly characteristics. |
| first_indexed | 2024-04-13T08:06:50Z |
| format | Article |
| id | doaj.art-5fc1116226f2482f9b2e784b7ba13503 |
| institution | Directory Open Access Journal |
| issn | 2399-3642 |
| language | English |
| last_indexed | 2024-04-13T08:06:50Z |
| publishDate | 2022-11-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Communications Biology |
| spelling | doaj.art-5fc1116226f2482f9b2e784b7ba135032022-12-22T02:55:08ZengNature PortfolioCommunications Biology2399-36422022-11-015111410.1038/s42003-022-04272-1Proteogenomic landscape and clinical characterization of GH-producing pituitary adenomas/somatotroph pituitary neuroendocrine tumorsAzusa Yamato0Hidekazu Nagano1Yue Gao2Tatsuma Matsuda3Naoko Hashimoto4Akitoshi Nakayama5Kazuyuki Yamagata6Masataka Yokoyama7Yingbo Gong8Xiaoyan Shi9Siti Nurul Zhahara10Takashi Kono11Yuki Taki12Naoto Furuki13Motoi Nishimura14Kentaro Horiguchi15Yasuo Iwadate16Masaki Fukuyo17Bahityar Rahmutulla18Atsushi Kaneda19Yoshinori Hasegawa20Yusuke Kawashima21Osamu Ohara22Tetsuo Ishikawa23Eiryo Kawakami24Yasuhiro Nakamura25Naoko Inoshita26Shozo Yamada27Noriaki Fukuhara28Hiroshi Nishioka29Tomoaki Tanaka30Department of Molecular Diagnosis, Graduate School of Medicine, Chiba UniversityDepartment of Molecular Diagnosis, Graduate School of Medicine, Chiba UniversityDepartment of Molecular Diagnosis, Graduate School of Medicine, Chiba UniversityDepartment of Molecular Diagnosis, Graduate School of Medicine, Chiba UniversityDepartment of Molecular Diagnosis, Graduate School of Medicine, Chiba UniversityDepartment of Molecular Diagnosis, Graduate School of Medicine, Chiba UniversityDepartment of Molecular Diagnosis, Graduate School of Medicine, Chiba UniversityDepartment of Molecular Diagnosis, Graduate School of Medicine, Chiba UniversityDepartment of Molecular Diagnosis, Graduate School of Medicine, Chiba UniversityDepartment of Molecular Diagnosis, Graduate School of Medicine, Chiba UniversityDepartment of Molecular Diagnosis, Graduate School of Medicine, Chiba UniversityDepartment of Molecular Diagnosis, Graduate School of Medicine, Chiba UniversityDepartment of Molecular Diagnosis, Graduate School of Medicine, Chiba UniversityDepartment of Molecular Diagnosis, Graduate School of Medicine, Chiba UniversityDivision of Laboratory Medicine, Chiba University HospitalDepartment of Neurological Surgery, Chiba University HospitalDepartment of Neurological Surgery, Chiba University HospitalDepartment of Molecular Oncology, Graduate School of Medicine, Chiba UniversityDepartment of Molecular Oncology, Graduate School of Medicine, Chiba UniversityDepartment of Molecular Oncology, Graduate School of Medicine, Chiba UniversityDepartment of Applied Genomics, Kazusa DNA Research InstituteDepartment of Applied Genomics, Kazusa DNA Research InstituteDepartment of Applied Genomics, Kazusa DNA Research InstituteAdvanced Data Science Project, RIKEN Information R&D and Strategy Headquarters, RIKENAdvanced Data Science Project, RIKEN Information R&D and Strategy Headquarters, RIKENDivision of Pathology, Faculty of Medicine, Tohoku Medical and Pharmaceutical UniversityDepartment of Pathology, Moriyama Memorial HospitalHypothalamic and Pituitary Center, Moriyama Neurological Center HospitalDepartment of Hypothalamic and Pituitary Surgery, Toranomon HospitalDepartment of Hypothalamic and Pituitary Surgery, Toranomon HospitalDepartment of Molecular Diagnosis, Graduate School of Medicine, Chiba UniversityThe genetic alterations, protein expressions, and clinical characteristics of growth hormone-producing pituitary adenomas/somatotroph pituitary neuroendocrine tumors are integrated to detect molecules associated with acromegaly characteristics.https://doi.org/10.1038/s42003-022-04272-1 |
| spellingShingle | Azusa Yamato Hidekazu Nagano Yue Gao Tatsuma Matsuda Naoko Hashimoto Akitoshi Nakayama Kazuyuki Yamagata Masataka Yokoyama Yingbo Gong Xiaoyan Shi Siti Nurul Zhahara Takashi Kono Yuki Taki Naoto Furuki Motoi Nishimura Kentaro Horiguchi Yasuo Iwadate Masaki Fukuyo Bahityar Rahmutulla Atsushi Kaneda Yoshinori Hasegawa Yusuke Kawashima Osamu Ohara Tetsuo Ishikawa Eiryo Kawakami Yasuhiro Nakamura Naoko Inoshita Shozo Yamada Noriaki Fukuhara Hiroshi Nishioka Tomoaki Tanaka Proteogenomic landscape and clinical characterization of GH-producing pituitary adenomas/somatotroph pituitary neuroendocrine tumors Communications Biology |
| title | Proteogenomic landscape and clinical characterization of GH-producing pituitary adenomas/somatotroph pituitary neuroendocrine tumors |
| title_full | Proteogenomic landscape and clinical characterization of GH-producing pituitary adenomas/somatotroph pituitary neuroendocrine tumors |
| title_fullStr | Proteogenomic landscape and clinical characterization of GH-producing pituitary adenomas/somatotroph pituitary neuroendocrine tumors |
| title_full_unstemmed | Proteogenomic landscape and clinical characterization of GH-producing pituitary adenomas/somatotroph pituitary neuroendocrine tumors |
| title_short | Proteogenomic landscape and clinical characterization of GH-producing pituitary adenomas/somatotroph pituitary neuroendocrine tumors |
| title_sort | proteogenomic landscape and clinical characterization of gh producing pituitary adenomas somatotroph pituitary neuroendocrine tumors |
| url | https://doi.org/10.1038/s42003-022-04272-1 |
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