Magnetic Resonance Imaging as a Predictor of Outcome in Congenital Lymphatic Malformations of the Neck
Objectives:. To identify factors on magnetic resonance imaging (MRI) that predict the outcomes of children with congenital lymphatic malformations (LMs) of the neck. Design:. Retrospective cohort study. Setting:. The Royal Children’s Hospital, Melbourne, a quaternary pediatric referral hospital. Pat...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Health/LWW
2023-03-01
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| Series: | Journal of Vascular Anomalies |
| Online Access: | http://journals.lww.com/10.1097/JOVA.0000000000000058 |
| _version_ | 1797870380578242560 |
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| author | Anthony Penington Angela Holmes John Vrazas |
| author_facet | Anthony Penington Angela Holmes John Vrazas |
| author_sort | Anthony Penington |
| collection | DOAJ |
| description | Objectives:. To identify factors on magnetic resonance imaging (MRI) that predict the outcomes of children with congenital lymphatic malformations (LMs) of the neck.
Design:. Retrospective cohort study.
Setting:. The Royal Children’s Hospital, Melbourne, a quaternary pediatric referral hospital.
Patients:. All children referred to the vascular anomalies service with LM identified at birth or in the first month of life were born between 1991 and 2015.
Outcome measurements:. Pattern of involvement on MRI imaging, need for intervention for respiratory difficulty, documented episodes of infection, and aesthetic outcomes.
Results:. MRI images were available for 27 of 30 patients with LM of the neck present at or soon after birth. Of these, 10 (37%) met the primary outcome of undergoing any intervention whose intention was stated to be for airway compromise, which occurred between 7 days and 4 years of age. The intervention was more likely when MRI showed parapharyngeal involvement (P < .001), although not all cases with parapharyngeal disease required respiratory intervention. Risk increases if other regions of the neck were also involved. Overall, 2 broad patterns of disease were identified, a “posterior pattern” which was typically macrocystic and unilateral, and an “anterior pattern” which was microcystic and bilateral and more likely to have airway compromise. Thirteen patients (48%) had documented episodes of infection.
Conclusion:. Patterns of disease on MRI are identified which are associated with a greater risk of requiring intervention for airway obstruction. Children with congenital LM of the neck are at high risk of infective episodes. |
| first_indexed | 2024-04-10T00:27:41Z |
| format | Article |
| id | doaj.art-5fc19d222e6c4784940f12a50c1516f7 |
| institution | Directory Open Access Journal |
| issn | 2690-2702 |
| language | English |
| last_indexed | 2024-04-10T00:27:41Z |
| publishDate | 2023-03-01 |
| publisher | Wolters Kluwer Health/LWW |
| record_format | Article |
| series | Journal of Vascular Anomalies |
| spelling | doaj.art-5fc19d222e6c4784940f12a50c1516f72023-03-15T08:08:43ZengWolters Kluwer Health/LWWJournal of Vascular Anomalies2690-27022023-03-0141e05810.1097/JOVA.0000000000000058202303000-00002Magnetic Resonance Imaging as a Predictor of Outcome in Congenital Lymphatic Malformations of the NeckAnthony Penington0Angela Holmes1John Vrazas2a Department of Paediatrics, University of Melbourne, Parkville, Australiaa Department of Paediatrics, University of Melbourne, Parkville, Australiad Department of Medical Imaging, Royal Children’s Hospital, Melbourne, AustraliaObjectives:. To identify factors on magnetic resonance imaging (MRI) that predict the outcomes of children with congenital lymphatic malformations (LMs) of the neck. Design:. Retrospective cohort study. Setting:. The Royal Children’s Hospital, Melbourne, a quaternary pediatric referral hospital. Patients:. All children referred to the vascular anomalies service with LM identified at birth or in the first month of life were born between 1991 and 2015. Outcome measurements:. Pattern of involvement on MRI imaging, need for intervention for respiratory difficulty, documented episodes of infection, and aesthetic outcomes. Results:. MRI images were available for 27 of 30 patients with LM of the neck present at or soon after birth. Of these, 10 (37%) met the primary outcome of undergoing any intervention whose intention was stated to be for airway compromise, which occurred between 7 days and 4 years of age. The intervention was more likely when MRI showed parapharyngeal involvement (P < .001), although not all cases with parapharyngeal disease required respiratory intervention. Risk increases if other regions of the neck were also involved. Overall, 2 broad patterns of disease were identified, a “posterior pattern” which was typically macrocystic and unilateral, and an “anterior pattern” which was microcystic and bilateral and more likely to have airway compromise. Thirteen patients (48%) had documented episodes of infection. Conclusion:. Patterns of disease on MRI are identified which are associated with a greater risk of requiring intervention for airway obstruction. Children with congenital LM of the neck are at high risk of infective episodes.http://journals.lww.com/10.1097/JOVA.0000000000000058 |
| spellingShingle | Anthony Penington Angela Holmes John Vrazas Magnetic Resonance Imaging as a Predictor of Outcome in Congenital Lymphatic Malformations of the Neck Journal of Vascular Anomalies |
| title | Magnetic Resonance Imaging as a Predictor of Outcome in Congenital Lymphatic Malformations of the Neck |
| title_full | Magnetic Resonance Imaging as a Predictor of Outcome in Congenital Lymphatic Malformations of the Neck |
| title_fullStr | Magnetic Resonance Imaging as a Predictor of Outcome in Congenital Lymphatic Malformations of the Neck |
| title_full_unstemmed | Magnetic Resonance Imaging as a Predictor of Outcome in Congenital Lymphatic Malformations of the Neck |
| title_short | Magnetic Resonance Imaging as a Predictor of Outcome in Congenital Lymphatic Malformations of the Neck |
| title_sort | magnetic resonance imaging as a predictor of outcome in congenital lymphatic malformations of the neck |
| url | http://journals.lww.com/10.1097/JOVA.0000000000000058 |
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