Keep calm and transcribe on: chromatin changes with age, but transcription can learn to live with it

Assessing age‐related tissue dysfunction represents an emerging field and involves analyses that are far from trivial, often requiring the integration of several large‐scale (“omic”) techniques. In their recent work, Tessarz and colleagues (Bozukova et al, 2022) characterize changes in the transcrip...

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Main Authors: Cian J Lynch, Manuel Serrano
Format: Article
Language:English
Published: Springer Nature 2022-09-01
Series:Molecular Systems Biology
Online Access:https://doi.org/10.15252/msb.202211276
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author Cian J Lynch
Manuel Serrano
author_facet Cian J Lynch
Manuel Serrano
author_sort Cian J Lynch
collection DOAJ
description Assessing age‐related tissue dysfunction represents an emerging field and involves analyses that are far from trivial, often requiring the integration of several large‐scale (“omic”) techniques. In their recent work, Tessarz and colleagues (Bozukova et al, 2022) characterize changes in the transcriptional machinery during aging in mice and report some surprising findings.
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spelling doaj.art-5fc54a492791409faae897d3537618082024-03-02T04:17:00ZengSpringer NatureMolecular Systems Biology1744-42922022-09-01189n/an/a10.15252/msb.202211276Keep calm and transcribe on: chromatin changes with age, but transcription can learn to live with itCian J Lynch0Manuel Serrano1Cellular Plasticity and Disease Group, Institute for Research in Biomedicine (IRB Barcelona) Barcelona Institute of Science and Technology (BIST) Barcelona SpainCellular Plasticity and Disease Group, Institute for Research in Biomedicine (IRB Barcelona) Barcelona Institute of Science and Technology (BIST) Barcelona SpainAssessing age‐related tissue dysfunction represents an emerging field and involves analyses that are far from trivial, often requiring the integration of several large‐scale (“omic”) techniques. In their recent work, Tessarz and colleagues (Bozukova et al, 2022) characterize changes in the transcriptional machinery during aging in mice and report some surprising findings.https://doi.org/10.15252/msb.202211276
spellingShingle Cian J Lynch
Manuel Serrano
Keep calm and transcribe on: chromatin changes with age, but transcription can learn to live with it
Molecular Systems Biology
title Keep calm and transcribe on: chromatin changes with age, but transcription can learn to live with it
title_full Keep calm and transcribe on: chromatin changes with age, but transcription can learn to live with it
title_fullStr Keep calm and transcribe on: chromatin changes with age, but transcription can learn to live with it
title_full_unstemmed Keep calm and transcribe on: chromatin changes with age, but transcription can learn to live with it
title_short Keep calm and transcribe on: chromatin changes with age, but transcription can learn to live with it
title_sort keep calm and transcribe on chromatin changes with age but transcription can learn to live with it
url https://doi.org/10.15252/msb.202211276
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