Regulatory T-Cells Suppress Cytotoxic T Lymphocyte Responses against Microglia

Regulatory T-Cells Suppress Cytotoxic T Lymphocyte Responses against Microglia

Regulatory T-cells (Tregs) play pivotal roles during infection, cancer, and autoimmunity. In our previous study, we demonstrated a role for the PD-1:PD-L1 pathway in controlling cytolytic responses of CD8<sup>+</sup> T lymphocytes against microglial cells presenting viral peptides. In th...

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Bibliographic Details
Main Authors: Priyanka Chauhan, Shuxian Hu, Wen S. Sheng, James R. Lokensgard
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Cells
Subjects:
microglia
regulatory T-cells
cytotoxicity
Online Access:https://www.mdpi.com/2073-4409/11/18/2826

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