A Mild and Regioselective Ring-Opening of Aziridines with Acid Anhydride Using TBD or PS-TBD as a Catalyst
The ring-opening of N-tosylaziridines with various acid anhydrides catalyzed by 5 mol % of 1,5,7-triazabicyclo[4,4,0]dec-5-ene (TBD) afforded the corresponding β-amino esters in excellent yields under mild reaction conditions. Polymer-supported catalyst, PS-TBD also acts as a good catalyst for this...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2015-10-01
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| Series: | Molecules |
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| Online Access: | http://www.mdpi.com/1420-3049/20/10/18482 |
| _version_ | 1818109237243412480 |
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| author | Satoru Matsukawa Yasutaka Mouri |
| author_facet | Satoru Matsukawa Yasutaka Mouri |
| author_sort | Satoru Matsukawa |
| collection | DOAJ |
| description | The ring-opening of N-tosylaziridines with various acid anhydrides catalyzed by 5 mol % of 1,5,7-triazabicyclo[4,4,0]dec-5-ene (TBD) afforded the corresponding β-amino esters in excellent yields under mild reaction conditions. Polymer-supported catalyst, PS-TBD also acts as a good catalyst for this reaction. PS-TBD was easily recovered and reused with minimal loss of activity. |
| first_indexed | 2024-12-11T02:28:03Z |
| format | Article |
| id | doaj.art-5fcb08f58aa24507b4682c0ac76f25cb |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-12-11T02:28:03Z |
| publishDate | 2015-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-5fcb08f58aa24507b4682c0ac76f25cb2022-12-22T01:23:53ZengMDPI AGMolecules1420-30492015-10-012010184821849510.3390/molecules201018482molecules201018482A Mild and Regioselective Ring-Opening of Aziridines with Acid Anhydride Using TBD or PS-TBD as a CatalystSatoru Matsukawa0Yasutaka Mouri1Department of Science Education, Faculty of Education, Ibaraki University, Ibaraki 310-8512, JapanDepartment of Science Education, Faculty of Education, Ibaraki University, Ibaraki 310-8512, JapanThe ring-opening of N-tosylaziridines with various acid anhydrides catalyzed by 5 mol % of 1,5,7-triazabicyclo[4,4,0]dec-5-ene (TBD) afforded the corresponding β-amino esters in excellent yields under mild reaction conditions. Polymer-supported catalyst, PS-TBD also acts as a good catalyst for this reaction. PS-TBD was easily recovered and reused with minimal loss of activity.http://www.mdpi.com/1420-3049/20/10/18482organocatalystbasecatalystpolymercatalystguanidineaziridineamino alcohols |
| spellingShingle | Satoru Matsukawa Yasutaka Mouri A Mild and Regioselective Ring-Opening of Aziridines with Acid Anhydride Using TBD or PS-TBD as a Catalyst Molecules organocatalyst basecatalyst polymercatalyst guanidine aziridine amino alcohols |
| title | A Mild and Regioselective Ring-Opening of Aziridines with Acid Anhydride Using TBD or PS-TBD as a Catalyst |
| title_full | A Mild and Regioselective Ring-Opening of Aziridines with Acid Anhydride Using TBD or PS-TBD as a Catalyst |
| title_fullStr | A Mild and Regioselective Ring-Opening of Aziridines with Acid Anhydride Using TBD or PS-TBD as a Catalyst |
| title_full_unstemmed | A Mild and Regioselective Ring-Opening of Aziridines with Acid Anhydride Using TBD or PS-TBD as a Catalyst |
| title_short | A Mild and Regioselective Ring-Opening of Aziridines with Acid Anhydride Using TBD or PS-TBD as a Catalyst |
| title_sort | mild and regioselective ring opening of aziridines with acid anhydride using tbd or ps tbd as a catalyst |
| topic | organocatalyst basecatalyst polymercatalyst guanidine aziridine amino alcohols |
| url | http://www.mdpi.com/1420-3049/20/10/18482 |
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