Radiofrequency ablation for pediatric recurrent hepatocellular carcinoma: a single-center experience
Abstract Purpose To summarize our single-center experience with percutaneous ultrasound (US)-guided radiofrequency ablation (RFA) for pediatric recurrent hepatocellular carcinoma (RHCC). Methods From September 2007 to September 2021, patients under 18 who underwent percutaneous US-guided RFA for RHC...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2023-12-01
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| Series: | BMC Medical Imaging |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12880-023-01159-3 |
| _version_ | 1797397677951942656 |
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| author | Haiyi Long Wenxin Wu Luyao Zhou Hui Shen Xiaoyan Xie Baoxian Liu |
| author_facet | Haiyi Long Wenxin Wu Luyao Zhou Hui Shen Xiaoyan Xie Baoxian Liu |
| author_sort | Haiyi Long |
| collection | DOAJ |
| description | Abstract Purpose To summarize our single-center experience with percutaneous ultrasound (US)-guided radiofrequency ablation (RFA) for pediatric recurrent hepatocellular carcinoma (RHCC). Methods From September 2007 to September 2021, patients under 18 who underwent percutaneous US-guided RFA for RHCC were retrospectively enrolled in this study. Local effectiveness, complications, local tumor progression (LTP), progression free survival (PFS), and overall survival (OS) were evaluated. Results A total of 10 patients (9 male and 1 female; mean age, 11.7 ± 4 years ; age range, 6–17 years) with 15 intrahepatic RHCC lesions were enrolled in this study. Complete ablation (CA) was achieved in 14 out of 15 lesions (93.3%) after the first RFA. During the follow-up (mean, 63.1 ± 18 months; range, 5.3-123.3 months), LTP did not occur. Five patients died including three with tumor progression and one with liver failure. The accumulative one- and three-year PFS rates were 30% and 10%, respectively. The accumulative one- and three-year OS rates were 77.8% and 44.4%, respectively. Conclusions Our single-center experience suggests the safety and feasibility of percutaneous US-guided RFA for pediatric RHCC. |
| first_indexed | 2024-03-09T01:13:37Z |
| format | Article |
| id | doaj.art-5fd25fb0a50c41dfb419e42762a8f671 |
| institution | Directory Open Access Journal |
| issn | 1471-2342 |
| language | English |
| last_indexed | 2024-03-09T01:13:37Z |
| publishDate | 2023-12-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Medical Imaging |
| spelling | doaj.art-5fd25fb0a50c41dfb419e42762a8f6712023-12-10T12:36:03ZengBMCBMC Medical Imaging1471-23422023-12-012311810.1186/s12880-023-01159-3Radiofrequency ablation for pediatric recurrent hepatocellular carcinoma: a single-center experienceHaiyi Long0Wenxin Wu1Luyao Zhou2Hui Shen3Xiaoyan Xie4Baoxian Liu5Department of Medical Ultrasonics, Institute of Diagnostic and Interventional Ultrasound, The First Affiliated Hospital of Sun Yat-sen UniversityDepartment of Medical Ultrasonics, Institute of Diagnostic and Interventional Ultrasound, The First Affiliated Hospital of Sun Yat-sen UniversityDepartment of Medical Ultrasonics, Institute of Diagnostic and Interventional Ultrasound, The First Affiliated Hospital of Sun Yat-sen UniversityDepartment of Medical Ultrasonics, Institute of Diagnostic and Interventional Ultrasound, The First Affiliated Hospital of Sun Yat-sen UniversityDepartment of Medical Ultrasonics, Institute of Diagnostic and Interventional Ultrasound, The First Affiliated Hospital of Sun Yat-sen UniversityDepartment of Medical Ultrasonics, Institute of Diagnostic and Interventional Ultrasound, The First Affiliated Hospital of Sun Yat-sen UniversityAbstract Purpose To summarize our single-center experience with percutaneous ultrasound (US)-guided radiofrequency ablation (RFA) for pediatric recurrent hepatocellular carcinoma (RHCC). Methods From September 2007 to September 2021, patients under 18 who underwent percutaneous US-guided RFA for RHCC were retrospectively enrolled in this study. Local effectiveness, complications, local tumor progression (LTP), progression free survival (PFS), and overall survival (OS) were evaluated. Results A total of 10 patients (9 male and 1 female; mean age, 11.7 ± 4 years ; age range, 6–17 years) with 15 intrahepatic RHCC lesions were enrolled in this study. Complete ablation (CA) was achieved in 14 out of 15 lesions (93.3%) after the first RFA. During the follow-up (mean, 63.1 ± 18 months; range, 5.3-123.3 months), LTP did not occur. Five patients died including three with tumor progression and one with liver failure. The accumulative one- and three-year PFS rates were 30% and 10%, respectively. The accumulative one- and three-year OS rates were 77.8% and 44.4%, respectively. Conclusions Our single-center experience suggests the safety and feasibility of percutaneous US-guided RFA for pediatric RHCC.https://doi.org/10.1186/s12880-023-01159-3Radiofrequency ablationRecurrent hepatocellular carcinomaChildrenSafetyLocal tumor progressionSurvival |
| spellingShingle | Haiyi Long Wenxin Wu Luyao Zhou Hui Shen Xiaoyan Xie Baoxian Liu Radiofrequency ablation for pediatric recurrent hepatocellular carcinoma: a single-center experience BMC Medical Imaging Radiofrequency ablation Recurrent hepatocellular carcinoma Children Safety Local tumor progression Survival |
| title | Radiofrequency ablation for pediatric recurrent hepatocellular carcinoma: a single-center experience |
| title_full | Radiofrequency ablation for pediatric recurrent hepatocellular carcinoma: a single-center experience |
| title_fullStr | Radiofrequency ablation for pediatric recurrent hepatocellular carcinoma: a single-center experience |
| title_full_unstemmed | Radiofrequency ablation for pediatric recurrent hepatocellular carcinoma: a single-center experience |
| title_short | Radiofrequency ablation for pediatric recurrent hepatocellular carcinoma: a single-center experience |
| title_sort | radiofrequency ablation for pediatric recurrent hepatocellular carcinoma a single center experience |
| topic | Radiofrequency ablation Recurrent hepatocellular carcinoma Children Safety Local tumor progression Survival |
| url | https://doi.org/10.1186/s12880-023-01159-3 |
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