Synaptic transmission molecules and their role in the pathogenesis of allergic rhinitis
Immune cells and molecules, as well as synaptic transmission molecules play a regulatory role in the communication pathways of the entire body when it is necessary to engage all body resources in the fight against infections or tumor cells wherever they appear. In potential allergy, the neuroimmune...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Siberian State Medical University (Tomsk)
2022-01-01
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| Series: | Бюллетень сибирской медицины |
| Subjects: | |
| Online Access: | https://bulletin.ssmu.ru/jour/article/view/4591 |
| _version_ | 1797872758479126528 |
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| author | A. V. Klimov O. V. Kalyuzhin V. V. Klimov O. A. Naidina |
| author_facet | A. V. Klimov O. V. Kalyuzhin V. V. Klimov O. A. Naidina |
| author_sort | A. V. Klimov |
| collection | DOAJ |
| description | Immune cells and molecules, as well as synaptic transmission molecules play a regulatory role in the communication pathways of the entire body when it is necessary to engage all body resources in the fight against infections or tumor cells wherever they appear. In potential allergy, the neuroimmune network controls allergen tolerance maintenance at both local and systemic levels.The review focuses on different neurotransmitters and our understanding of a balance and imbalance between the immune system and the nervous system in allergic inflammation, including allergic rhinitis. However, the pathogenesis of the two endotypes of rhinitis (conventional allergic rhinitis and local allergic rhinitis) and the impact of the neuroimmune network on it remain unresolved. |
| first_indexed | 2024-04-10T01:05:15Z |
| format | Article |
| id | doaj.art-5fd430f5f22b49d5a6a95578e7836419 |
| institution | Directory Open Access Journal |
| issn | 1682-0363 1819-3684 |
| language | English |
| last_indexed | 2024-04-10T01:05:15Z |
| publishDate | 2022-01-01 |
| publisher | Siberian State Medical University (Tomsk) |
| record_format | Article |
| series | Бюллетень сибирской медицины |
| spelling | doaj.art-5fd430f5f22b49d5a6a95578e78364192023-03-13T09:58:27ZengSiberian State Medical University (Tomsk)Бюллетень сибирской медицины1682-03631819-36842022-01-0120414315210.20538/1682-0363-2021-4-143-1522850Synaptic transmission molecules and their role in the pathogenesis of allergic rhinitisA. V. Klimov0O. V. Kalyuzhin1V. V. Klimov2O. A. Naidina3Сибирский государственный медицинский университет (СибГМУ)Первый Московский медицинский государственный университет им. И.М. Сеченова (Сеченовский университет)Сибирский государственный медицинский университет (СибГМУ)Сибирский государственный медицинский университет (СибГМУ)Immune cells and molecules, as well as synaptic transmission molecules play a regulatory role in the communication pathways of the entire body when it is necessary to engage all body resources in the fight against infections or tumor cells wherever they appear. In potential allergy, the neuroimmune network controls allergen tolerance maintenance at both local and systemic levels.The review focuses on different neurotransmitters and our understanding of a balance and imbalance between the immune system and the nervous system in allergic inflammation, including allergic rhinitis. However, the pathogenesis of the two endotypes of rhinitis (conventional allergic rhinitis and local allergic rhinitis) and the impact of the neuroimmune network on it remain unresolved.https://bulletin.ssmu.ru/jour/article/view/4591аллергический ринитнейротрансмиттерынейрогормонынейропептидырецепторы для нейромолекул |
| spellingShingle | A. V. Klimov O. V. Kalyuzhin V. V. Klimov O. A. Naidina Synaptic transmission molecules and their role in the pathogenesis of allergic rhinitis Бюллетень сибирской медицины аллергический ринит нейротрансмиттеры нейрогормоны нейропептиды рецепторы для нейромолекул |
| title | Synaptic transmission molecules and their role in the pathogenesis of allergic rhinitis |
| title_full | Synaptic transmission molecules and their role in the pathogenesis of allergic rhinitis |
| title_fullStr | Synaptic transmission molecules and their role in the pathogenesis of allergic rhinitis |
| title_full_unstemmed | Synaptic transmission molecules and their role in the pathogenesis of allergic rhinitis |
| title_short | Synaptic transmission molecules and their role in the pathogenesis of allergic rhinitis |
| title_sort | synaptic transmission molecules and their role in the pathogenesis of allergic rhinitis |
| topic | аллергический ринит нейротрансмиттеры нейрогормоны нейропептиды рецепторы для нейромолекул |
| url | https://bulletin.ssmu.ru/jour/article/view/4591 |
| work_keys_str_mv | AT avklimov synaptictransmissionmoleculesandtheirroleinthepathogenesisofallergicrhinitis AT ovkalyuzhin synaptictransmissionmoleculesandtheirroleinthepathogenesisofallergicrhinitis AT vvklimov synaptictransmissionmoleculesandtheirroleinthepathogenesisofallergicrhinitis AT oanaidina synaptictransmissionmoleculesandtheirroleinthepathogenesisofallergicrhinitis |