A New Kid on the Block: Sacituzumab Govitecan for the Treatment of Breast Cancer and Other Solid Tumors

A New Kid on the Block: Sacituzumab Govitecan for the Treatment of Breast Cancer and Other Solid Tumors

Human trophoblast cell-surface antigen-2 (Trop-2) is a membrane glycoprotein involved in cell proliferation and motility, frequently overexpressed in epithelial tumors. Thus, it represents an attractive target for anticancer therapies. Sacituzumab govitecan (SG) is a third-generation antibody-drug c...

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Bibliographic Details
Main Authors: Giuliana Pavone, Lucia Motta, Federica Martorana, Gianmarco Motta, Paolo Vigneri
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Molecules
Subjects:
antibody-drug conjugates
Sacituzumab govitecan
Trop-2
breast cancer
Online Access:https://www.mdpi.com/1420-3049/26/23/7294

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