Biosynthesis of cannabinoid precursor olivetolic acid in genetically engineered Yarrowia lipolytica

A yeast host Yarrowia lipolytica is genetically engineered to overcome rate-limiting steps and synthesize the cannabinoid precursor olivetolic acid.

Bibliographic Details
Main Authors: Jingbo Ma, Yang Gu, Peng Xu
Format: Article
Language:English
Published: Nature Portfolio 2022-11-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-022-04202-1
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author Jingbo Ma
Yang Gu
Peng Xu
author_facet Jingbo Ma
Yang Gu
Peng Xu
author_sort Jingbo Ma
collection DOAJ
description A yeast host Yarrowia lipolytica is genetically engineered to overcome rate-limiting steps and synthesize the cannabinoid precursor olivetolic acid.
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issn 2399-3642
language English
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spelling doaj.art-5fdb4ecc5061410ab9c32c3427ee79042022-12-22T02:31:02ZengNature PortfolioCommunications Biology2399-36422022-11-01511710.1038/s42003-022-04202-1Biosynthesis of cannabinoid precursor olivetolic acid in genetically engineered Yarrowia lipolyticaJingbo Ma0Yang Gu1Peng Xu2Department of Chemical, Biochemical and Environmental Engineering, University of MarylandDepartment of Chemical, Biochemical and Environmental Engineering, University of MarylandDepartment of Chemical, Biochemical and Environmental Engineering, University of MarylandA yeast host Yarrowia lipolytica is genetically engineered to overcome rate-limiting steps and synthesize the cannabinoid precursor olivetolic acid.https://doi.org/10.1038/s42003-022-04202-1
spellingShingle Jingbo Ma
Yang Gu
Peng Xu
Biosynthesis of cannabinoid precursor olivetolic acid in genetically engineered Yarrowia lipolytica
Communications Biology
title Biosynthesis of cannabinoid precursor olivetolic acid in genetically engineered Yarrowia lipolytica
title_full Biosynthesis of cannabinoid precursor olivetolic acid in genetically engineered Yarrowia lipolytica
title_fullStr Biosynthesis of cannabinoid precursor olivetolic acid in genetically engineered Yarrowia lipolytica
title_full_unstemmed Biosynthesis of cannabinoid precursor olivetolic acid in genetically engineered Yarrowia lipolytica
title_short Biosynthesis of cannabinoid precursor olivetolic acid in genetically engineered Yarrowia lipolytica
title_sort biosynthesis of cannabinoid precursor olivetolic acid in genetically engineered yarrowia lipolytica
url https://doi.org/10.1038/s42003-022-04202-1
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AT yanggu biosynthesisofcannabinoidprecursorolivetolicacidingeneticallyengineeredyarrowialipolytica
AT pengxu biosynthesisofcannabinoidprecursorolivetolicacidingeneticallyengineeredyarrowialipolytica