Biosynthesis of cannabinoid precursor olivetolic acid in genetically engineered Yarrowia lipolytica
A yeast host Yarrowia lipolytica is genetically engineered to overcome rate-limiting steps and synthesize the cannabinoid precursor olivetolic acid.
Main Authors: | , , |
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Format: | Article |
Language: | English |
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Nature Portfolio
2022-11-01
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Series: | Communications Biology |
Online Access: | https://doi.org/10.1038/s42003-022-04202-1 |
_version_ | 1817970588347531264 |
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author | Jingbo Ma Yang Gu Peng Xu |
author_facet | Jingbo Ma Yang Gu Peng Xu |
author_sort | Jingbo Ma |
collection | DOAJ |
description | A yeast host Yarrowia lipolytica is genetically engineered to overcome rate-limiting steps and synthesize the cannabinoid precursor olivetolic acid. |
first_indexed | 2024-04-13T20:36:00Z |
format | Article |
id | doaj.art-5fdb4ecc5061410ab9c32c3427ee7904 |
institution | Directory Open Access Journal |
issn | 2399-3642 |
language | English |
last_indexed | 2024-04-13T20:36:00Z |
publishDate | 2022-11-01 |
publisher | Nature Portfolio |
record_format | Article |
series | Communications Biology |
spelling | doaj.art-5fdb4ecc5061410ab9c32c3427ee79042022-12-22T02:31:02ZengNature PortfolioCommunications Biology2399-36422022-11-01511710.1038/s42003-022-04202-1Biosynthesis of cannabinoid precursor olivetolic acid in genetically engineered Yarrowia lipolyticaJingbo Ma0Yang Gu1Peng Xu2Department of Chemical, Biochemical and Environmental Engineering, University of MarylandDepartment of Chemical, Biochemical and Environmental Engineering, University of MarylandDepartment of Chemical, Biochemical and Environmental Engineering, University of MarylandA yeast host Yarrowia lipolytica is genetically engineered to overcome rate-limiting steps and synthesize the cannabinoid precursor olivetolic acid.https://doi.org/10.1038/s42003-022-04202-1 |
spellingShingle | Jingbo Ma Yang Gu Peng Xu Biosynthesis of cannabinoid precursor olivetolic acid in genetically engineered Yarrowia lipolytica Communications Biology |
title | Biosynthesis of cannabinoid precursor olivetolic acid in genetically engineered Yarrowia lipolytica |
title_full | Biosynthesis of cannabinoid precursor olivetolic acid in genetically engineered Yarrowia lipolytica |
title_fullStr | Biosynthesis of cannabinoid precursor olivetolic acid in genetically engineered Yarrowia lipolytica |
title_full_unstemmed | Biosynthesis of cannabinoid precursor olivetolic acid in genetically engineered Yarrowia lipolytica |
title_short | Biosynthesis of cannabinoid precursor olivetolic acid in genetically engineered Yarrowia lipolytica |
title_sort | biosynthesis of cannabinoid precursor olivetolic acid in genetically engineered yarrowia lipolytica |
url | https://doi.org/10.1038/s42003-022-04202-1 |
work_keys_str_mv | AT jingboma biosynthesisofcannabinoidprecursorolivetolicacidingeneticallyengineeredyarrowialipolytica AT yanggu biosynthesisofcannabinoidprecursorolivetolicacidingeneticallyengineeredyarrowialipolytica AT pengxu biosynthesisofcannabinoidprecursorolivetolicacidingeneticallyengineeredyarrowialipolytica |