The two-component system CpxRA negatively regulates the Locus of Enterocyte Effacement of enterohemorrhagic Escherichia coli involving sigma 32 and Lon protease

The two-component system CpxRA negatively regulates the Locus of Enterocyte Effacement of enterohemorrhagic Escherichia coli involving sigma 32 and Lon protease

Enterohemorrhagic Escherichia coli (EHEC) is a significant cause of serious human gastrointestinal disease worldwide. EHEC strains contain a pathogenicity island called the locus of enterocyte effacement (LEE), which encodes virulence factors responsible for damaging the gut mucosa. The Cpx envelope...

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Bibliographic Details
Main Authors: MIGUEL A. eDE LA CRUZ, JASON K. eMORGAN, Miguel A. eAres, Jorge Antonio eYañez, JAMES T. eRIORDAN, JORGE A. eGIRON
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-02-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
EHEC
LEE
Lon protease
CpxRA
sigma factor 32
Online Access:http://journal.frontiersin.org/Journal/10.3389/fcimb.2016.00011/full

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