Type I Interferons Are Involved in the Intracellular Growth Control of Mycobacterium abscessus by Mediating NOD2-Induced Production of Nitric Oxide in Macrophages

Type I Interferons Are Involved in the Intracellular Growth Control of Mycobacterium abscessus by Mediating NOD2-Induced Production of Nitric Oxide in Macrophages

Mycobacterium abscessus (MAB) is one of the rapidly growing, multidrug-resistant non-tuberculous mycobacteria (NTM) causing various diseases including pulmonary disorder. Although it has been known that type I interferons (IFNs) contribute to host defense against bacterial infections, the role of ty...

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Main Authors: Jae-Hun Ahn, Ji-Yeon Park, Dong-Yeon Kim, Tae-Sung Lee, Do-Hyeon Jung, Yeong-Jun Kim, Yeon-Ji Lee, Yun-Ji Lee, In-Su Seo, Eun-Jung Song, Ah-Ra Jang, Soo-Jin Yang, Sung Jae Shin, Jong-Hwan Park
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Immunology
Subjects:
Mycobacterium abscessus
type I IFN
NOD2
nitric oxide
macrophage
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.738070/full

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