Theoretical Framework for the Study of Genetic Diseases Caused by Dominant Alleles
We propose a theoretical basis for analyzing several features of genetic diseases caused by dominant alleles, including: disease prevalence, genotype penetrance, and the relationship between causal genotype frequency and disease frequency. In addition, we provide a theoretical framework for accurate...
Main Authors: | Michael F. Roberts, Stephen E. Bricher |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-03-01
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Series: | Life |
Subjects: | |
Online Access: | https://www.mdpi.com/2075-1729/13/3/733 |
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