Synthesis and evaluation of ?-hydroxy fatty acid-derived heterocyclic compounds with potential industrial interest
T2-Hydroxyheptadecanoic acid chloride (2) reacted with anthranilic acid to produce 2-substituted-3,1-benzoxazin-4-one (3) which was used as starting material to synthesize some condensed and non-condensed heterocyclic compounds by reaction with nitrogen nucleophiles e.g., hydrazine hydrate, and form...
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| Format: | Article |
| Language: | English |
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Consejo Superior de Investigaciones Científicas
2006-12-01
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| Series: | Grasas y Aceites |
| Subjects: | |
| Online Access: | http://grasasyaceites.revistas.csic.es/index.php/grasasyaceites/article/view/61 |
| _version_ | 1818591156967047168 |
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| author | A. M. F. Eissa R. El-Sayed |
| author_facet | A. M. F. Eissa R. El-Sayed |
| author_sort | A. M. F. Eissa |
| collection | DOAJ |
| description | T2-Hydroxyheptadecanoic acid chloride (2) reacted with anthranilic acid to produce 2-substituted-3,1-benzoxazin-4-one (3) which was used as starting material to synthesize some condensed and non-condensed heterocyclic compounds by reaction with nitrogen nucleophiles e.g., hydrazine hydrate, and formamide. The products were subjected to reaction with different moles of propylene oxide (n = 5, 10, 15) to produce a novel group of nonionic compounds having a double function as antibacterial and surface active agents which can be used in the manufacturing of drugs, cosmetics, pesticides or can be used as antibacterial and/or antifungal additives. The surface active properties as surface and interfacial tension, cloud point, foaming height, wetting time, and emulsification power were determined, the antimicrobial and biodegradability were also screened. |
| first_indexed | 2024-12-16T10:07:58Z |
| format | Article |
| id | doaj.art-5fe9fd7fa13d491c842254fb8dc7040d |
| institution | Directory Open Access Journal |
| issn | 0017-3495 1988-4214 |
| language | English |
| last_indexed | 2024-12-16T10:07:58Z |
| publishDate | 2006-12-01 |
| publisher | Consejo Superior de Investigaciones Científicas |
| record_format | Article |
| series | Grasas y Aceites |
| spelling | doaj.art-5fe9fd7fa13d491c842254fb8dc7040d2022-12-21T22:35:37ZengConsejo Superior de Investigaciones CientíficasGrasas y Aceites0017-34951988-42142006-12-0157436737510.3989/gya.2006.v57.i4.6159Synthesis and evaluation of ?-hydroxy fatty acid-derived heterocyclic compounds with potential industrial interestA. M. F. Eissa0R. El-Sayed1Chemistry Department, Faculty of Science, Benha UniversityChemistry Department, Faculty of Science, Benha UniversityT2-Hydroxyheptadecanoic acid chloride (2) reacted with anthranilic acid to produce 2-substituted-3,1-benzoxazin-4-one (3) which was used as starting material to synthesize some condensed and non-condensed heterocyclic compounds by reaction with nitrogen nucleophiles e.g., hydrazine hydrate, and formamide. The products were subjected to reaction with different moles of propylene oxide (n = 5, 10, 15) to produce a novel group of nonionic compounds having a double function as antibacterial and surface active agents which can be used in the manufacturing of drugs, cosmetics, pesticides or can be used as antibacterial and/or antifungal additives. The surface active properties as surface and interfacial tension, cloud point, foaming height, wetting time, and emulsification power were determined, the antimicrobial and biodegradability were also screened.http://grasasyaceites.revistas.csic.es/index.php/grasasyaceites/article/view/61antimicrobial propertiesheterocyclic derivativesphysical propertiessurface active agents |
| spellingShingle | A. M. F. Eissa R. El-Sayed Synthesis and evaluation of ?-hydroxy fatty acid-derived heterocyclic compounds with potential industrial interest Grasas y Aceites antimicrobial properties heterocyclic derivatives physical properties surface active agents |
| title | Synthesis and evaluation of ?-hydroxy fatty acid-derived heterocyclic compounds with potential industrial interest |
| title_full | Synthesis and evaluation of ?-hydroxy fatty acid-derived heterocyclic compounds with potential industrial interest |
| title_fullStr | Synthesis and evaluation of ?-hydroxy fatty acid-derived heterocyclic compounds with potential industrial interest |
| title_full_unstemmed | Synthesis and evaluation of ?-hydroxy fatty acid-derived heterocyclic compounds with potential industrial interest |
| title_short | Synthesis and evaluation of ?-hydroxy fatty acid-derived heterocyclic compounds with potential industrial interest |
| title_sort | synthesis and evaluation of hydroxy fatty acid derived heterocyclic compounds with potential industrial interest |
| topic | antimicrobial properties heterocyclic derivatives physical properties surface active agents |
| url | http://grasasyaceites.revistas.csic.es/index.php/grasasyaceites/article/view/61 |
| work_keys_str_mv | AT amfeissa synthesisandevaluationofhydroxyfattyacidderivedheterocycliccompoundswithpotentialindustrialinterest AT relsayed synthesisandevaluationofhydroxyfattyacidderivedheterocycliccompoundswithpotentialindustrialinterest |