Liver Disorders that Induced by Burkholderia Mallei and the Role of Phenolic Compounds of Rheum Ribes in Treatment

The present study was designed to show the potential role of phenolic compounds against the toxicity of Burkholderia mallei. The study used 30 adult male rats that distributed to five groups (each group consist 6 rats); control group that received normal saline, second group rat injected intraperit...

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Main Author: Ahmed Hamad Saleh
Format: Article
Language:English
Published: University of Thi-Qar 2020-12-01
Series:مجلة علوم ذي قار
Subjects:
Online Access:https://jsci.utq.edu.iq/index.php/main/article/view/706
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author Ahmed Hamad Saleh
author_facet Ahmed Hamad Saleh
author_sort Ahmed Hamad Saleh
collection DOAJ
description The present study was designed to show the potential role of phenolic compounds against the toxicity of Burkholderia mallei. The study used 30 adult male rats that distributed to five groups (each group consist 6 rats); control group that received normal saline, second group rat injected intraperitoneal with B. mallei at dose 10 6 cell/ ml. third group rat injected intraperitoneal with B. mallei at dose 1 08 cell/ ml. fourth group rat injected intraperitoneal with B. mallei at dose 1 0 6 cell/ ml and treated with 250ug/ml of phenolic compounds for four weeks. Keywords—component, formatting, style, styling, insert (key words). Fifth group rat injected intraperitoneal with B. mallei at dose 1 08 cell/ ml and treated with 250ug/ml of phenolic compounds for four weeks. Sixth group rat treated with 250ug/ml of phenolic compounds for four weeks. The results show high significant increased (P < 0.05) in levels AST, ALT, ALP and MDA with high significant decreased (P < 0.05) in levels GSH, catalase in second and third groups compared with control group. The results of fourth, fifth and sixth groups show non-significant changes (P < 0.05) in all parameters compare with control group when using Rheum ribes. It was concluded that Rheum ribes has been potential role against the toxicity of B. mallei in adult male rats.
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spelling doaj.art-5fee5f02229a440aaf11935d6d6831bc2023-11-10T13:21:16ZengUniversity of Thi-Qarمجلة علوم ذي قار1991-86902709-02562020-12-0172Liver Disorders that Induced by Burkholderia Mallei and the Role of Phenolic Compounds of Rheum Ribes in TreatmentAhmed Hamad Saleh The present study was designed to show the potential role of phenolic compounds against the toxicity of Burkholderia mallei. The study used 30 adult male rats that distributed to five groups (each group consist 6 rats); control group that received normal saline, second group rat injected intraperitoneal with B. mallei at dose 10 6 cell/ ml. third group rat injected intraperitoneal with B. mallei at dose 1 08 cell/ ml. fourth group rat injected intraperitoneal with B. mallei at dose 1 0 6 cell/ ml and treated with 250ug/ml of phenolic compounds for four weeks. Keywords—component, formatting, style, styling, insert (key words). Fifth group rat injected intraperitoneal with B. mallei at dose 1 08 cell/ ml and treated with 250ug/ml of phenolic compounds for four weeks. Sixth group rat treated with 250ug/ml of phenolic compounds for four weeks. The results show high significant increased (P < 0.05) in levels AST, ALT, ALP and MDA with high significant decreased (P < 0.05) in levels GSH, catalase in second and third groups compared with control group. The results of fourth, fifth and sixth groups show non-significant changes (P < 0.05) in all parameters compare with control group when using Rheum ribes. It was concluded that Rheum ribes has been potential role against the toxicity of B. mallei in adult male rats. https://jsci.utq.edu.iq/index.php/main/article/view/706phenolic compounds; oxidative stress; antioxidant; liver functions
spellingShingle Ahmed Hamad Saleh
Liver Disorders that Induced by Burkholderia Mallei and the Role of Phenolic Compounds of Rheum Ribes in Treatment
مجلة علوم ذي قار
phenolic compounds; oxidative stress; antioxidant; liver functions
title Liver Disorders that Induced by Burkholderia Mallei and the Role of Phenolic Compounds of Rheum Ribes in Treatment
title_full Liver Disorders that Induced by Burkholderia Mallei and the Role of Phenolic Compounds of Rheum Ribes in Treatment
title_fullStr Liver Disorders that Induced by Burkholderia Mallei and the Role of Phenolic Compounds of Rheum Ribes in Treatment
title_full_unstemmed Liver Disorders that Induced by Burkholderia Mallei and the Role of Phenolic Compounds of Rheum Ribes in Treatment
title_short Liver Disorders that Induced by Burkholderia Mallei and the Role of Phenolic Compounds of Rheum Ribes in Treatment
title_sort liver disorders that induced by burkholderia mallei and the role of phenolic compounds of rheum ribes in treatment
topic phenolic compounds; oxidative stress; antioxidant; liver functions
url https://jsci.utq.edu.iq/index.php/main/article/view/706
work_keys_str_mv AT ahmedhamadsaleh liverdisordersthatinducedbyburkholderiamalleiandtheroleofphenoliccompoundsofrheumribesintreatment