Case report of vancomycin-induced pancytopenia

Abstract: Vancomycin is the first-line agent for the treatment of bacteremia, endocarditis, pneumonia, cellulitis, and osteomyelitis. Pancytopenia is an uncommon adverse effect of vancomycin therapy, with only a few cases of vancomycin-related neutropenia and pancytopenia described in the literature...

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Main Authors: Sorab Gupta, Shorabh Sharma, Nandini Menon, Shradha Ahuja, Michelle Dahdouh
Format: Article
Language:English
Published: Sociedade Brasileira de Medicina Tropical (SBMT) 2016-04-01
Series:Revista da Sociedade Brasileira de Medicina Tropical
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822016000200258&lng=en&tlng=en
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author Sorab Gupta
Shorabh Sharma
Nandini Menon
Shradha Ahuja
Michelle Dahdouh
author_facet Sorab Gupta
Shorabh Sharma
Nandini Menon
Shradha Ahuja
Michelle Dahdouh
author_sort Sorab Gupta
collection DOAJ
description Abstract: Vancomycin is the first-line agent for the treatment of bacteremia, endocarditis, pneumonia, cellulitis, and osteomyelitis. Pancytopenia is an uncommon adverse effect of vancomycin therapy, with only a few cases of vancomycin-related neutropenia and pancytopenia described in the literature. We describe a case of a 56-year-old man who was diagnosed with chronic paraspinal abscess and started on intravenous vancomycin. He was re-admitted two weeks later with new-onset pancytopenia. Discontinuation of vancomycin resulted in improved cell counts. Physicians should monitor cell counts in patients who are on long-term intravenous vancomycin.
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spelling doaj.art-5ff2aa78410e4e488d31729686df86062022-12-22T03:35:38ZengSociedade Brasileira de Medicina Tropical (SBMT)Revista da Sociedade Brasileira de Medicina Tropical1678-98492016-04-0149225825910.1590/0037-8682-0263-2015S0037-86822016000200258Case report of vancomycin-induced pancytopeniaSorab GuptaShorabh SharmaNandini MenonShradha AhujaMichelle DahdouhAbstract: Vancomycin is the first-line agent for the treatment of bacteremia, endocarditis, pneumonia, cellulitis, and osteomyelitis. Pancytopenia is an uncommon adverse effect of vancomycin therapy, with only a few cases of vancomycin-related neutropenia and pancytopenia described in the literature. We describe a case of a 56-year-old man who was diagnosed with chronic paraspinal abscess and started on intravenous vancomycin. He was re-admitted two weeks later with new-onset pancytopenia. Discontinuation of vancomycin resulted in improved cell counts. Physicians should monitor cell counts in patients who are on long-term intravenous vancomycin.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822016000200258&lng=en&tlng=enVancomycinPancytopeniaRare side effect
spellingShingle Sorab Gupta
Shorabh Sharma
Nandini Menon
Shradha Ahuja
Michelle Dahdouh
Case report of vancomycin-induced pancytopenia
Revista da Sociedade Brasileira de Medicina Tropical
Vancomycin
Pancytopenia
Rare side effect
title Case report of vancomycin-induced pancytopenia
title_full Case report of vancomycin-induced pancytopenia
title_fullStr Case report of vancomycin-induced pancytopenia
title_full_unstemmed Case report of vancomycin-induced pancytopenia
title_short Case report of vancomycin-induced pancytopenia
title_sort case report of vancomycin induced pancytopenia
topic Vancomycin
Pancytopenia
Rare side effect
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822016000200258&lng=en&tlng=en
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