An observational study to assess validity and reliability of smartphone sensor-based gait and balance assessments in multiple sclerosis: Floodlight GaitLab protocol
Background Gait and balance impairments are often present in people with multiple sclerosis (PwMS) and have a significant impact on quality of life and independence. Gold-standard quantitative tools for assessing gait and balance such as motion capture systems and force plates usually require comple...
| Main Authors: | , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2023-10-01
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| Series: | Digital Health |
| Online Access: | https://doi.org/10.1177/20552076231205284 |
| _version_ | 1797655843185885184 |
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| author | Mike D Rinderknecht Mattia Zanon Tjitske A Boonstra Lorenza Angelini Dimitar Stanev Gabriela González Chan Lisa Bunn Frank Dondelinger Richard Hosking Jenny Freeman Jeremy Hobart Jonathan Marsden Licinio Craveiro |
| author_facet | Mike D Rinderknecht Mattia Zanon Tjitske A Boonstra Lorenza Angelini Dimitar Stanev Gabriela González Chan Lisa Bunn Frank Dondelinger Richard Hosking Jenny Freeman Jeremy Hobart Jonathan Marsden Licinio Craveiro |
| author_sort | Mike D Rinderknecht |
| collection | DOAJ |
| description | Background Gait and balance impairments are often present in people with multiple sclerosis (PwMS) and have a significant impact on quality of life and independence. Gold-standard quantitative tools for assessing gait and balance such as motion capture systems and force plates usually require complex technical setups. Wearable sensors, including those integrated into smartphones, offer a more frequent, convenient, and minimally burdensome assessment of functional disability in a home environment. We developed a novel smartphone sensor-based application (Floodlight) that is being used in multiple research and clinical contexts, but a complete validation of this technology is still lacking. Methods This protocol describes an observational study designed to evaluate the analytical and clinical validity of Floodlight gait and balance tests. Approximately 100 PwMS and 35 healthy controls will perform multiple gait and balance tasks in both laboratory-based and real-world environments in order to explore the following properties: (a) concurrent validity of the Floodlight gait and balance tests against gold-standard assessments; (b) reliability of Floodlight digital measures derived under different controlled gait and balance conditions, and different on-body sensor locations; (c) ecological validity of the tests; and (d) construct validity compared with clinician- and patient-reported assessments. Conclusions The Floodlight GaitLab study (ISRCTN15993728) represents a critical step in the technical validation of Floodlight technology to measure gait and balance in PwMS, and will also allow the development of new test designs and algorithms. |
| first_indexed | 2024-03-11T17:20:30Z |
| format | Article |
| id | doaj.art-5ff4109d806240d0a98eef393246032c |
| institution | Directory Open Access Journal |
| issn | 2055-2076 |
| language | English |
| last_indexed | 2024-03-11T17:20:30Z |
| publishDate | 2023-10-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Digital Health |
| spelling | doaj.art-5ff4109d806240d0a98eef393246032c2023-10-19T13:34:27ZengSAGE PublishingDigital Health2055-20762023-10-01910.1177/20552076231205284An observational study to assess validity and reliability of smartphone sensor-based gait and balance assessments in multiple sclerosis: Floodlight GaitLab protocolMike D Rinderknecht0Mattia Zanon1Tjitske A Boonstra2Lorenza Angelini3Dimitar Stanev4Gabriela González Chan5Lisa Bunn6Frank Dondelinger7Richard Hosking8Jenny Freeman9Jeremy Hobart10Jonathan Marsden11Licinio Craveiro12 , Basel, Switzerland , Basel, Switzerland , Woerden, Netherlands , Basel, Switzerland , Basel, Switzerland Faculty of Health, , Plymouth, UK Faculty of Health, , Plymouth, UK , Basel, Switzerland , Plymouth, UK Faculty of Health, , Plymouth, UK , Plymouth, UK Faculty of Health, , Plymouth, UK , Basel, SwitzerlandBackground Gait and balance impairments are often present in people with multiple sclerosis (PwMS) and have a significant impact on quality of life and independence. Gold-standard quantitative tools for assessing gait and balance such as motion capture systems and force plates usually require complex technical setups. Wearable sensors, including those integrated into smartphones, offer a more frequent, convenient, and minimally burdensome assessment of functional disability in a home environment. We developed a novel smartphone sensor-based application (Floodlight) that is being used in multiple research and clinical contexts, but a complete validation of this technology is still lacking. Methods This protocol describes an observational study designed to evaluate the analytical and clinical validity of Floodlight gait and balance tests. Approximately 100 PwMS and 35 healthy controls will perform multiple gait and balance tasks in both laboratory-based and real-world environments in order to explore the following properties: (a) concurrent validity of the Floodlight gait and balance tests against gold-standard assessments; (b) reliability of Floodlight digital measures derived under different controlled gait and balance conditions, and different on-body sensor locations; (c) ecological validity of the tests; and (d) construct validity compared with clinician- and patient-reported assessments. Conclusions The Floodlight GaitLab study (ISRCTN15993728) represents a critical step in the technical validation of Floodlight technology to measure gait and balance in PwMS, and will also allow the development of new test designs and algorithms.https://doi.org/10.1177/20552076231205284 |
| spellingShingle | Mike D Rinderknecht Mattia Zanon Tjitske A Boonstra Lorenza Angelini Dimitar Stanev Gabriela González Chan Lisa Bunn Frank Dondelinger Richard Hosking Jenny Freeman Jeremy Hobart Jonathan Marsden Licinio Craveiro An observational study to assess validity and reliability of smartphone sensor-based gait and balance assessments in multiple sclerosis: Floodlight GaitLab protocol Digital Health |
| title | An observational study to assess validity and reliability of smartphone sensor-based gait and balance assessments in multiple sclerosis: Floodlight GaitLab protocol |
| title_full | An observational study to assess validity and reliability of smartphone sensor-based gait and balance assessments in multiple sclerosis: Floodlight GaitLab protocol |
| title_fullStr | An observational study to assess validity and reliability of smartphone sensor-based gait and balance assessments in multiple sclerosis: Floodlight GaitLab protocol |
| title_full_unstemmed | An observational study to assess validity and reliability of smartphone sensor-based gait and balance assessments in multiple sclerosis: Floodlight GaitLab protocol |
| title_short | An observational study to assess validity and reliability of smartphone sensor-based gait and balance assessments in multiple sclerosis: Floodlight GaitLab protocol |
| title_sort | observational study to assess validity and reliability of smartphone sensor based gait and balance assessments in multiple sclerosis floodlight gaitlab protocol |
| url | https://doi.org/10.1177/20552076231205284 |
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