Synthesis of Azuleno[2,1-<i>b</i>]quinolones and Quinolines via Brønsted Acid-Catalyzed Cyclization of 2-Arylaminoazulenes

Synthesis of Azuleno[2,1-<i>b</i>]quinolones and Quinolines via Brønsted Acid-Catalyzed Cyclization of 2-Arylaminoazulenes

Quinolone and quinoline derivatives are frequently found as substructures in pharmaceutically active compounds. In this paper, we describe a procedure for the synthesis of azuleno[2,1-<i>b</i>]quinolones and quinolines from 2-arylaminoazulene derivatives, which are readily prepared via t...

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Bibliographic Details
Main Authors: Taku Shoji, Mutsumi Takeuchi, Mayumi Uda, Yukino Ariga, Akari Yamazaki, Ryuta Sekiguchi, Shunji Ito
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Molecules
Subjects:
azulene
quinolone
quinoline
cyclization
aromatic nucleophilic substitution
Online Access:https://www.mdpi.com/1420-3049/28/15/5785

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