Blood transfusion reactions in children: Associated factors
Objective: To analyze the profile of blood transfusion reactions in children and to identify the involved factors. Methods: This was a cross-sectional study in a tertiary pediatric teaching hospital from the public healthcare system, involving all children admitted from January to July of 2011 (5,43...
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| Format: | Article |
| Language: | Portuguese |
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Brazilian Society of Pediatrics
2013-07-01
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| Series: | Jornal de Pediatria (Versão em Português) |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2255553613000815 |
| _version_ | 1811324124694315008 |
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| author | Anna K.K.V. Pedrosa Francisco J.M. Pinto Luiza D.B. Lins Grace M. Deus |
| author_facet | Anna K.K.V. Pedrosa Francisco J.M. Pinto Luiza D.B. Lins Grace M. Deus |
| author_sort | Anna K.K.V. Pedrosa |
| collection | DOAJ |
| description | Objective: To analyze the profile of blood transfusion reactions in children and to identify the involved factors.
Methods: This was a cross-sectional study in a tertiary pediatric teaching hospital from the public healthcare system, involving all children admitted from January to July of 2011 (5,437), of which 1,226 received blood transfusions, constituting the sample. A documental study was performed by analyzing files from the hemovigilance service and notification forms of transfusion reactions. The variables investigated were: number and type of blood components transfused, transfusion site, reaction site, age, gender, type of blood components involved, type of incident, and previous history of multiple transfusions. A descriptive and inferential analysis was performed, using statistical tests to establish the association between the variables.
Results: There were 57 transfusion incidents involving 47 children and 72 different blood products, thus constituting a prevalence of reactions of 3.8%. At the inferential analysis, the chi-squared test showed that the following variables were significantly associated (p < 0.05) with the type of reaction: age range and type of blood component. Similarly, the patient's underlying disease was associated with previous history of transfusion incident and type of blood component.
Conclusions: The prevalence of transfusion reactions in children is high, and the intervening factors are: type of blood component, age, patient comorbidity, and multiple transfusions; type of blood component and age are also associated with type of reaction. |
| first_indexed | 2024-04-13T14:07:29Z |
| format | Article |
| id | doaj.art-5ff81cf4fab841b2bc8efb96fc3e6362 |
| institution | Directory Open Access Journal |
| issn | 2255-5536 |
| language | Portuguese |
| last_indexed | 2024-04-13T14:07:29Z |
| publishDate | 2013-07-01 |
| publisher | Brazilian Society of Pediatrics |
| record_format | Article |
| series | Jornal de Pediatria (Versão em Português) |
| spelling | doaj.art-5ff81cf4fab841b2bc8efb96fc3e63622022-12-22T02:43:51ZporBrazilian Society of PediatricsJornal de Pediatria (Versão em Português)2255-55362013-07-0189440040610.1016/j.jpedp.2012.12.012Blood transfusion reactions in children: Associated factorsAnna K.K.V. Pedrosa0Francisco J.M. Pinto1Luiza D.B. Lins2Grace M. Deus3Acadêmica do Curso de Medicina, Universidade Estadual do Ceará (UECE), Fortaleza, CE, BrasilPós-doutor em Saúde Pública, Universidade de São Paulo (USP), São Paulo, SP, Brasil. Professor, Mestrado Acadêmico em Saúde Pública, Mestrado Profissional em Saúde da Criança e do Adolescente e do Curso de Graduação em Medicina, UECE, Fortaleza, CE, BrasilHematologista, Universidade Federal do Ceará (UFCE), Fortaleza, CE, Brasil. Médica-assistente, Centro de Hematologia Hemoterapia do Ceará (HEMOCE) e Hospital Infantil Albert Sabin, Fortaleza, CE, BrasilPediatra, UFCE, Fortaleza, CE, Brasil. Médica-assistente e Gerente de Risco, Hospital Infantil Albert Sabin, Fortaleza, CE, BrasilObjective: To analyze the profile of blood transfusion reactions in children and to identify the involved factors. Methods: This was a cross-sectional study in a tertiary pediatric teaching hospital from the public healthcare system, involving all children admitted from January to July of 2011 (5,437), of which 1,226 received blood transfusions, constituting the sample. A documental study was performed by analyzing files from the hemovigilance service and notification forms of transfusion reactions. The variables investigated were: number and type of blood components transfused, transfusion site, reaction site, age, gender, type of blood components involved, type of incident, and previous history of multiple transfusions. A descriptive and inferential analysis was performed, using statistical tests to establish the association between the variables. Results: There were 57 transfusion incidents involving 47 children and 72 different blood products, thus constituting a prevalence of reactions of 3.8%. At the inferential analysis, the chi-squared test showed that the following variables were significantly associated (p < 0.05) with the type of reaction: age range and type of blood component. Similarly, the patient's underlying disease was associated with previous history of transfusion incident and type of blood component. Conclusions: The prevalence of transfusion reactions in children is high, and the intervening factors are: type of blood component, age, patient comorbidity, and multiple transfusions; type of blood component and age are also associated with type of reaction.http://www.sciencedirect.com/science/article/pii/S2255553613000815Blood transfusionHemovigilancePediatrics |
| spellingShingle | Anna K.K.V. Pedrosa Francisco J.M. Pinto Luiza D.B. Lins Grace M. Deus Blood transfusion reactions in children: Associated factors Jornal de Pediatria (Versão em Português) Blood transfusion Hemovigilance Pediatrics |
| title | Blood transfusion reactions in children: Associated factors |
| title_full | Blood transfusion reactions in children: Associated factors |
| title_fullStr | Blood transfusion reactions in children: Associated factors |
| title_full_unstemmed | Blood transfusion reactions in children: Associated factors |
| title_short | Blood transfusion reactions in children: Associated factors |
| title_sort | blood transfusion reactions in children associated factors |
| topic | Blood transfusion Hemovigilance Pediatrics |
| url | http://www.sciencedirect.com/science/article/pii/S2255553613000815 |
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