Recent Advances in Visible-Light Photoredox Catalysis for the Thiol-Ene/Yne Reactions
Visible-light photoredox catalysis has been established as a popular and powerful tool for organic transformations owing to its inherent characterization of environmental friendliness and sustainability in the past decades. The thiol-ene/yne reactions, the direct hydrothiolation of alkenes/alkynes w...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-01-01
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| Series: | Molecules |
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| Online Access: | https://www.mdpi.com/1420-3049/27/3/619 |
| _version_ | 1797486223309144064 |
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| author | Qian Xiao Qing-Xiao Tong Jian-Ji Zhong |
| author_facet | Qian Xiao Qing-Xiao Tong Jian-Ji Zhong |
| author_sort | Qian Xiao |
| collection | DOAJ |
| description | Visible-light photoredox catalysis has been established as a popular and powerful tool for organic transformations owing to its inherent characterization of environmental friendliness and sustainability in the past decades. The thiol-ene/yne reactions, the direct hydrothiolation of alkenes/alkynes with thiols, represents one of the most efficient and atom-economic approaches for the carbon-sulfur bonds construction. In traditional methodologies, harsh conditions such as stoichiometric reagents or a specialized UV photo-apparatus were necessary suffering from various disadvantages. In particular, visible-light photoredox catalysis has also been demonstrated to be a greener and milder protocol for the thiol-ene/yne reactions in recent years. Additionally, unprecedented advancements have been achieved in this area during the past decade. In this review, we will summarize the recent advances in visible-light photoredox catalyzed thiol-ene/yne reactions from 2015 to 2021. Synthetic strategies, substrate scope, and proposed reaction pathways are mainly discussed. |
| first_indexed | 2024-03-09T23:30:10Z |
| format | Article |
| id | doaj.art-5ffd17a8ce4c42f2890ac387658cda02 |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-03-09T23:30:10Z |
| publishDate | 2022-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-5ffd17a8ce4c42f2890ac387658cda022023-11-23T17:09:43ZengMDPI AGMolecules1420-30492022-01-0127361910.3390/molecules27030619Recent Advances in Visible-Light Photoredox Catalysis for the Thiol-Ene/Yne ReactionsQian Xiao0Qing-Xiao Tong1Jian-Ji Zhong2School of Chemistry and Environmental Engineering, Hanshan Normal University, Chaozhou 521041, ChinaKey Laboratory for Preparation and Application of Ordered Structural Materials of Guangdong Province, Department of Chemistry, Shantou University, Shantou 515063, ChinaKey Laboratory for Preparation and Application of Ordered Structural Materials of Guangdong Province, Department of Chemistry, Shantou University, Shantou 515063, ChinaVisible-light photoredox catalysis has been established as a popular and powerful tool for organic transformations owing to its inherent characterization of environmental friendliness and sustainability in the past decades. The thiol-ene/yne reactions, the direct hydrothiolation of alkenes/alkynes with thiols, represents one of the most efficient and atom-economic approaches for the carbon-sulfur bonds construction. In traditional methodologies, harsh conditions such as stoichiometric reagents or a specialized UV photo-apparatus were necessary suffering from various disadvantages. In particular, visible-light photoredox catalysis has also been demonstrated to be a greener and milder protocol for the thiol-ene/yne reactions in recent years. Additionally, unprecedented advancements have been achieved in this area during the past decade. In this review, we will summarize the recent advances in visible-light photoredox catalyzed thiol-ene/yne reactions from 2015 to 2021. Synthetic strategies, substrate scope, and proposed reaction pathways are mainly discussed.https://www.mdpi.com/1420-3049/27/3/619photoredox catalysisthiol-ene/yne reactionsynthetic methodologiesgreen chemistry |
| spellingShingle | Qian Xiao Qing-Xiao Tong Jian-Ji Zhong Recent Advances in Visible-Light Photoredox Catalysis for the Thiol-Ene/Yne Reactions Molecules photoredox catalysis thiol-ene/yne reaction synthetic methodologies green chemistry |
| title | Recent Advances in Visible-Light Photoredox Catalysis for the Thiol-Ene/Yne Reactions |
| title_full | Recent Advances in Visible-Light Photoredox Catalysis for the Thiol-Ene/Yne Reactions |
| title_fullStr | Recent Advances in Visible-Light Photoredox Catalysis for the Thiol-Ene/Yne Reactions |
| title_full_unstemmed | Recent Advances in Visible-Light Photoredox Catalysis for the Thiol-Ene/Yne Reactions |
| title_short | Recent Advances in Visible-Light Photoredox Catalysis for the Thiol-Ene/Yne Reactions |
| title_sort | recent advances in visible light photoredox catalysis for the thiol ene yne reactions |
| topic | photoredox catalysis thiol-ene/yne reaction synthetic methodologies green chemistry |
| url | https://www.mdpi.com/1420-3049/27/3/619 |
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