Features of the female prostate according to age: an autopsy study

ABSTRACT INTRODUCTION: The prostate gland plays an important role in male and female reproductive system. Data on this organ have not been fully explored in women since its first description, probably because it is considered a vestigial gland. OBJECTIVE: To correlate the morphology of the female...

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Main Authors: Thalita Cristina M. Costa, Patrícia M. Cury, Ana Maria G. Custódio
Format: Article
Language:English
Published: Sociedade Brasileira de Patologia Clínica
Series:Jornal Brasileiro de Patologia e Medicina Laboratorial
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1676-24442016000400246&lng=en&tlng=en
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author Thalita Cristina M. Costa
Patrícia M. Cury
Ana Maria G. Custódio
author_facet Thalita Cristina M. Costa
Patrícia M. Cury
Ana Maria G. Custódio
author_sort Thalita Cristina M. Costa
collection DOAJ
description ABSTRACT INTRODUCTION: The prostate gland plays an important role in male and female reproductive system. Data on this organ have not been fully explored in women since its first description, probably because it is considered a vestigial gland. OBJECTIVE: To correlate the morphology of the female prostate with age in autopsy. MATERIAL AND METHODS: Thirty-two female cadavers, 31 adults and one newborn, underwent dissection of the region corresponding to the prostate for histological analysis. The urethral region was divided into three portions: proximal, median, and distal. All the glands present in the samples were counted. Clinical data were collected, including age and previous diagnosis of menopause. RESULTS: There were no macroscopically visible prostate. Morphological analyses showed glands surrounding the urethra with a stratified epithelium, ranging from squamous to columnar types, with prevalence of basophilic cells and some presenting with secretion inside. A significant correlation with prostate tissue was found between the median and the proximal urethra, as well as between the median and distal urethra, suggesting that when the glandular structures increase in the median region, there is also an increase in the anterior and distal structures. Moreover, a prevalence of the glands in the median urethra was observed in post-menopausal women. CONCLUSION: This study suggests that the number of female prostate glands increases after menopause, with proliferative spread and growth of the median portion to the proximal and distal portions.
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spelling doaj.art-5fff943ed5c44daa902bc912c84ac9322022-12-22T03:01:46ZengSociedade Brasileira de Patologia ClínicaJornal Brasileiro de Patologia e Medicina Laboratorial1676-24441678-477452424625210.5935/1676-2444.20160041S1676-24442016000400246Features of the female prostate according to age: an autopsy studyThalita Cristina M. CostaPatrícia M. CuryAna Maria G. CustódioABSTRACT INTRODUCTION: The prostate gland plays an important role in male and female reproductive system. Data on this organ have not been fully explored in women since its first description, probably because it is considered a vestigial gland. OBJECTIVE: To correlate the morphology of the female prostate with age in autopsy. MATERIAL AND METHODS: Thirty-two female cadavers, 31 adults and one newborn, underwent dissection of the region corresponding to the prostate for histological analysis. The urethral region was divided into three portions: proximal, median, and distal. All the glands present in the samples were counted. Clinical data were collected, including age and previous diagnosis of menopause. RESULTS: There were no macroscopically visible prostate. Morphological analyses showed glands surrounding the urethra with a stratified epithelium, ranging from squamous to columnar types, with prevalence of basophilic cells and some presenting with secretion inside. A significant correlation with prostate tissue was found between the median and the proximal urethra, as well as between the median and distal urethra, suggesting that when the glandular structures increase in the median region, there is also an increase in the anterior and distal structures. Moreover, a prevalence of the glands in the median urethra was observed in post-menopausal women. CONCLUSION: This study suggests that the number of female prostate glands increases after menopause, with proliferative spread and growth of the median portion to the proximal and distal portions.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1676-24442016000400246&lng=en&tlng=enpróstatamulheresmenopausa
spellingShingle Thalita Cristina M. Costa
Patrícia M. Cury
Ana Maria G. Custódio
Features of the female prostate according to age: an autopsy study
Jornal Brasileiro de Patologia e Medicina Laboratorial
próstata
mulheres
menopausa
title Features of the female prostate according to age: an autopsy study
title_full Features of the female prostate according to age: an autopsy study
title_fullStr Features of the female prostate according to age: an autopsy study
title_full_unstemmed Features of the female prostate according to age: an autopsy study
title_short Features of the female prostate according to age: an autopsy study
title_sort features of the female prostate according to age an autopsy study
topic próstata
mulheres
menopausa
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1676-24442016000400246&lng=en&tlng=en
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AT anamariagcustodio featuresofthefemaleprostateaccordingtoageanautopsystudy