Dietary Patterns, Gut Microbiota Remodeling, and Cardiometabolic Disease
The cardiovascular and metabolic disorders, collectively known as cardiometabolic disease (CMD), are high morbidity and mortality pathologies associated with lower quality of life and increasing health-care costs. The influence of the gut microbiota (GM) in dictating the interpersonal variability in...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-06-01
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| Series: | Metabolites |
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| Online Access: | https://www.mdpi.com/2218-1989/13/6/760 |
| _version_ | 1797593512014774272 |
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| author | Letizia Guiducci Giuseppina Nicolini Francesca Forini |
| author_facet | Letizia Guiducci Giuseppina Nicolini Francesca Forini |
| author_sort | Letizia Guiducci |
| collection | DOAJ |
| description | The cardiovascular and metabolic disorders, collectively known as cardiometabolic disease (CMD), are high morbidity and mortality pathologies associated with lower quality of life and increasing health-care costs. The influence of the gut microbiota (GM) in dictating the interpersonal variability in CMD susceptibility, progression and treatment response is beginning to be deciphered, as is the mutualistic relation established between the GM and diet. In particular, dietary factors emerge as pivotal determinants shaping the architecture and function of resident microorganisms in the human gut. In turn, intestinal microbes influence the absorption, metabolism, and storage of ingested nutrients, with potentially profound effects on host physiology. Herein, we present an updated overview on major effects of dietary components on the GM, highlighting the beneficial and detrimental consequences of diet–microbiota crosstalk in the setting of CMD. We also discuss the promises and challenges of integrating microbiome data in dietary planning aimed at restraining CMD onset and progression with a more personalized nutritional approach. |
| first_indexed | 2024-03-11T02:10:21Z |
| format | Article |
| id | doaj.art-6002e704ba3048a3aa049e9dee4e1b04 |
| institution | Directory Open Access Journal |
| issn | 2218-1989 |
| language | English |
| last_indexed | 2024-03-11T02:10:21Z |
| publishDate | 2023-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Metabolites |
| spelling | doaj.art-6002e704ba3048a3aa049e9dee4e1b042023-11-18T11:35:17ZengMDPI AGMetabolites2218-19892023-06-0113676010.3390/metabo13060760Dietary Patterns, Gut Microbiota Remodeling, and Cardiometabolic DiseaseLetizia Guiducci0Giuseppina Nicolini1Francesca Forini2CNR Institute of Clinical Physiology, Via Moruzzi 1, 56124 Pisa, ItalyCNR Institute of Clinical Physiology, Via Moruzzi 1, 56124 Pisa, ItalyCNR Institute of Clinical Physiology, Via Moruzzi 1, 56124 Pisa, ItalyThe cardiovascular and metabolic disorders, collectively known as cardiometabolic disease (CMD), are high morbidity and mortality pathologies associated with lower quality of life and increasing health-care costs. The influence of the gut microbiota (GM) in dictating the interpersonal variability in CMD susceptibility, progression and treatment response is beginning to be deciphered, as is the mutualistic relation established between the GM and diet. In particular, dietary factors emerge as pivotal determinants shaping the architecture and function of resident microorganisms in the human gut. In turn, intestinal microbes influence the absorption, metabolism, and storage of ingested nutrients, with potentially profound effects on host physiology. Herein, we present an updated overview on major effects of dietary components on the GM, highlighting the beneficial and detrimental consequences of diet–microbiota crosstalk in the setting of CMD. We also discuss the promises and challenges of integrating microbiome data in dietary planning aimed at restraining CMD onset and progression with a more personalized nutritional approach.https://www.mdpi.com/2218-1989/13/6/760gut microbiota/heart axisdysbiosiscardiometabolic risk and diseasenutritional habits |
| spellingShingle | Letizia Guiducci Giuseppina Nicolini Francesca Forini Dietary Patterns, Gut Microbiota Remodeling, and Cardiometabolic Disease Metabolites gut microbiota/heart axis dysbiosis cardiometabolic risk and disease nutritional habits |
| title | Dietary Patterns, Gut Microbiota Remodeling, and Cardiometabolic Disease |
| title_full | Dietary Patterns, Gut Microbiota Remodeling, and Cardiometabolic Disease |
| title_fullStr | Dietary Patterns, Gut Microbiota Remodeling, and Cardiometabolic Disease |
| title_full_unstemmed | Dietary Patterns, Gut Microbiota Remodeling, and Cardiometabolic Disease |
| title_short | Dietary Patterns, Gut Microbiota Remodeling, and Cardiometabolic Disease |
| title_sort | dietary patterns gut microbiota remodeling and cardiometabolic disease |
| topic | gut microbiota/heart axis dysbiosis cardiometabolic risk and disease nutritional habits |
| url | https://www.mdpi.com/2218-1989/13/6/760 |
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