Biological Basis and Clinical Application of Serum Tumor Markers

Cancer is the result of the accumulation ofchanges in molecules with important functionsin processes such as cell proliferation, apoptosis,cell death and gene repair. Molecules,substances or altered pathways constitutetumor markers or biomarkers useful in clinicalmonitoring of cancer patients, becau...

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Main Authors: Paola Andrea Cruz Tapias, Victoria Eugenia Villegas Gálvez, Sandra Rocío Ramírez Clavijo
Format: Article
Language:Spanish
Published: Universidad Colegio Mayor Nuestra Señora del Rosario 2008-07-01
Series:Revista Ciencias de la Salud
Subjects:
Online Access:http://www.urosario.edu.co/medicina/CienciasSalud/documentos/Vol6N2/08_FundamBiolog_vol6n2.pdf
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author Paola Andrea Cruz Tapias
Victoria Eugenia Villegas Gálvez
Sandra Rocío Ramírez Clavijo
author_facet Paola Andrea Cruz Tapias
Victoria Eugenia Villegas Gálvez
Sandra Rocío Ramírez Clavijo
author_sort Paola Andrea Cruz Tapias
collection DOAJ
description Cancer is the result of the accumulation ofchanges in molecules with important functionsin processes such as cell proliferation, apoptosis,cell death and gene repair. Molecules,substances or altered pathways constitutetumor markers or biomarkers useful in clinicalmonitoring of cancer patients, because theyhave demonstrated to be suitable for the valuationof the patient’s treatment and it efficiency.Determination of tumor markers has not beenvery successful due to the low sensitivity andspecificity of the techniques used and the requirementof large volumes of biological samplesor the use of invasive methods for collecting them. The serum tumor markers arise, as a usefultool to obtain information about the diseaseprogress and constitute as a scientific challengeto improve its applicability in early diagnosis,prognosis, monitoring of the disease and evaluationof therapeutic efficacy.
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spelling doaj.art-600419d00a1743b8986b4e1ca5875fa32022-12-21T21:31:15ZspaUniversidad Colegio Mayor Nuestra Señora del RosarioRevista Ciencias de la Salud1692-72732008-07-01628598Biological Basis and Clinical Application of Serum Tumor MarkersPaola Andrea Cruz TapiasVictoria Eugenia Villegas GálvezSandra Rocío Ramírez ClavijoCancer is the result of the accumulation ofchanges in molecules with important functionsin processes such as cell proliferation, apoptosis,cell death and gene repair. Molecules,substances or altered pathways constitutetumor markers or biomarkers useful in clinicalmonitoring of cancer patients, because theyhave demonstrated to be suitable for the valuationof the patient’s treatment and it efficiency.Determination of tumor markers has not beenvery successful due to the low sensitivity andspecificity of the techniques used and the requirementof large volumes of biological samplesor the use of invasive methods for collecting them. The serum tumor markers arise, as a usefultool to obtain information about the diseaseprogress and constitute as a scientific challengeto improve its applicability in early diagnosis,prognosis, monitoring of the disease and evaluationof therapeutic efficacy.http://www.urosario.edu.co/medicina/CienciasSalud/documentos/Vol6N2/08_FundamBiolog_vol6n2.pdfbiological tumor markers/serum markersdiagnostic useclassification
spellingShingle Paola Andrea Cruz Tapias
Victoria Eugenia Villegas Gálvez
Sandra Rocío Ramírez Clavijo
Biological Basis and Clinical Application of Serum Tumor Markers
Revista Ciencias de la Salud
biological tumor markers/serum markers
diagnostic use
classification
title Biological Basis and Clinical Application of Serum Tumor Markers
title_full Biological Basis and Clinical Application of Serum Tumor Markers
title_fullStr Biological Basis and Clinical Application of Serum Tumor Markers
title_full_unstemmed Biological Basis and Clinical Application of Serum Tumor Markers
title_short Biological Basis and Clinical Application of Serum Tumor Markers
title_sort biological basis and clinical application of serum tumor markers
topic biological tumor markers/serum markers
diagnostic use
classification
url http://www.urosario.edu.co/medicina/CienciasSalud/documentos/Vol6N2/08_FundamBiolog_vol6n2.pdf
work_keys_str_mv AT paolaandreacruztapias biologicalbasisandclinicalapplicationofserumtumormarkers
AT victoriaeugeniavillegasgalvez biologicalbasisandclinicalapplicationofserumtumormarkers
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