Capsaicin Ameliorates the Cyclophosphamide-Induced Cardiotoxicity by Inhibiting Free Radicals Generation, Inflammatory Cytokines, and Apoptotic Pathway in Rats

Capsaicin Ameliorates the Cyclophosphamide-Induced Cardiotoxicity by Inhibiting Free Radicals Generation, Inflammatory Cytokines, and Apoptotic Pathway in Rats

Cyclophosphamide is an antineoplastic agent that has a broad range of therapeutic applications; however, it has numerous side effects, including cardiotoxicity. Furthermore, chili peppers contain a substance called capsaicin, having antioxidant and anti-inflammatory effects. Thus, this research pape...

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Bibliographic Details
Main Authors: Rayan A. Ahmed, Mohammad Firoz Alam, Saeed Alshahrani, Abdulmajeed M. Jali, Abdullah M. Qahl, Mohammad Khalid, Hisham M. A. Muzafar, Hussain N. Alhamami, Tarique Anwer
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Life
Subjects:
cyclophosphamide
capsaicin
free radicals
oxidative stress
inflammatory cytokines
apoptosis
Online Access:https://www.mdpi.com/2075-1729/13/3/786

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