Coronary computed tomography angiography study on the relationship between the Ramus Intermedius and Atherosclerosis in the bifurcation of the left main coronary artery
Abstract Objective This study aimed to explore the relationship between the ramus intermedius (RI) and atherosclerosis in the bifurcation of the left coronary artery (LCA). Methods Screening patients who underwent CCTA from January to September 2021, 100 patients with RI (RI group) and 100 patients...
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| Format: | Article |
| Language: | English |
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BMC
2023-04-01
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| Series: | BMC Medical Imaging |
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| Online Access: | https://doi.org/10.1186/s12880-023-01009-2 |
| _version_ | 1827966046096588800 |
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| author | Dan-Qing Zhang Yan-Feng Xu Ya-Peng Dong Shu-Jing Yu |
| author_facet | Dan-Qing Zhang Yan-Feng Xu Ya-Peng Dong Shu-Jing Yu |
| author_sort | Dan-Qing Zhang |
| collection | DOAJ |
| description | Abstract Objective This study aimed to explore the relationship between the ramus intermedius (RI) and atherosclerosis in the bifurcation of the left coronary artery (LCA). Methods Screening patients who underwent CCTA from January to September 2021, 100 patients with RI (RI group) and 100 patients without RI (no-RI group) were randomly enrolled, Evaluation of RI distribution characteristics and left main coronary artery(LM),Left anterior descending branch(LAD),left circumflex branch(LCX) proximal segment plaque distribution, measurement of LAD-LCX bifurcation angle(∠LAD-LCX),Comparison of the three distribution characteristics with the incidence of plaques in the left main trunk bifurcation area (LM, LAD, LCX) between groups and within the RI group. Results The difference in the incidence of plaques in the proximal LCX and the LM between the RI group and the no-RI group were not statistically significant (P > 0.05). The incidence of plaques in the proximal LAD in the RI group was significantly higher than that in the non-RI group (77% versus 53%, P < 0.05). However, there was no statistically significant difference between the two groups after PSM. A univariate logistic regression analysis revealed that an RI was a risk factor for plaque formation in the proximal LAD (P < 0.001), and a multivariate logistic regression analysis revealed that an RI was not an independent risk factor for plaque formation in the proximal LAD (P > 0.05). When compared within the RI group, the difference in the incidence of plaques in the proximal segment of LAD, the proximal segment of LCX, and the LM among the different distribution groups of RI was not statistically significant, respectively (P > 0.05). Conclusion RI is not an independent risk factor for atherosclerosis in the left coronary artery bifurcation zone, but it may indirectly increase the risk of atherosclerosis in the proximal segment of the LAD. |
| first_indexed | 2024-04-09T17:43:52Z |
| format | Article |
| id | doaj.art-600474032e1c40b5bf8b1c232b73f1c8 |
| institution | Directory Open Access Journal |
| issn | 1471-2342 |
| language | English |
| last_indexed | 2024-04-09T17:43:52Z |
| publishDate | 2023-04-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Medical Imaging |
| spelling | doaj.art-600474032e1c40b5bf8b1c232b73f1c82023-04-16T11:28:11ZengBMCBMC Medical Imaging1471-23422023-04-012311810.1186/s12880-023-01009-2Coronary computed tomography angiography study on the relationship between the Ramus Intermedius and Atherosclerosis in the bifurcation of the left main coronary arteryDan-Qing Zhang0Yan-Feng Xu1Ya-Peng Dong2Shu-Jing Yu3Hebei Medical UniversityDepartment of Diagnostic CT, Cangzhou Central HospitalDepartment of Diagnostic CT, Cangzhou Central HospitalHebei Medical UniversityAbstract Objective This study aimed to explore the relationship between the ramus intermedius (RI) and atherosclerosis in the bifurcation of the left coronary artery (LCA). Methods Screening patients who underwent CCTA from January to September 2021, 100 patients with RI (RI group) and 100 patients without RI (no-RI group) were randomly enrolled, Evaluation of RI distribution characteristics and left main coronary artery(LM),Left anterior descending branch(LAD),left circumflex branch(LCX) proximal segment plaque distribution, measurement of LAD-LCX bifurcation angle(∠LAD-LCX),Comparison of the three distribution characteristics with the incidence of plaques in the left main trunk bifurcation area (LM, LAD, LCX) between groups and within the RI group. Results The difference in the incidence of plaques in the proximal LCX and the LM between the RI group and the no-RI group were not statistically significant (P > 0.05). The incidence of plaques in the proximal LAD in the RI group was significantly higher than that in the non-RI group (77% versus 53%, P < 0.05). However, there was no statistically significant difference between the two groups after PSM. A univariate logistic regression analysis revealed that an RI was a risk factor for plaque formation in the proximal LAD (P < 0.001), and a multivariate logistic regression analysis revealed that an RI was not an independent risk factor for plaque formation in the proximal LAD (P > 0.05). When compared within the RI group, the difference in the incidence of plaques in the proximal segment of LAD, the proximal segment of LCX, and the LM among the different distribution groups of RI was not statistically significant, respectively (P > 0.05). Conclusion RI is not an independent risk factor for atherosclerosis in the left coronary artery bifurcation zone, but it may indirectly increase the risk of atherosclerosis in the proximal segment of the LAD.https://doi.org/10.1186/s12880-023-01009-2Ramus intermediusBifurcation angleCoronary computed tomography angiographyAtherosclerosis |
| spellingShingle | Dan-Qing Zhang Yan-Feng Xu Ya-Peng Dong Shu-Jing Yu Coronary computed tomography angiography study on the relationship between the Ramus Intermedius and Atherosclerosis in the bifurcation of the left main coronary artery BMC Medical Imaging Ramus intermedius Bifurcation angle Coronary computed tomography angiography Atherosclerosis |
| title | Coronary computed tomography angiography study on the relationship between the Ramus Intermedius and Atherosclerosis in the bifurcation of the left main coronary artery |
| title_full | Coronary computed tomography angiography study on the relationship between the Ramus Intermedius and Atherosclerosis in the bifurcation of the left main coronary artery |
| title_fullStr | Coronary computed tomography angiography study on the relationship between the Ramus Intermedius and Atherosclerosis in the bifurcation of the left main coronary artery |
| title_full_unstemmed | Coronary computed tomography angiography study on the relationship between the Ramus Intermedius and Atherosclerosis in the bifurcation of the left main coronary artery |
| title_short | Coronary computed tomography angiography study on the relationship between the Ramus Intermedius and Atherosclerosis in the bifurcation of the left main coronary artery |
| title_sort | coronary computed tomography angiography study on the relationship between the ramus intermedius and atherosclerosis in the bifurcation of the left main coronary artery |
| topic | Ramus intermedius Bifurcation angle Coronary computed tomography angiography Atherosclerosis |
| url | https://doi.org/10.1186/s12880-023-01009-2 |
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