Identification of Mispairing Omic Signatures in Chinese Hamster Ovary (CHO) Cells Producing a Tri-Specific Antibody

Identification of Mispairing Omic Signatures in Chinese Hamster Ovary (CHO) Cells Producing a Tri-Specific Antibody

Monoclonal antibody-based therapy has shown efficacy against cancer, autoimmune, infectious, and inflammatory diseases. Multispecific antibodies (MsAbs), including trispecifics (tsAbs), offer enhanced therapeutic potential by targeting different epitopes. However, when co-expressed from three or mor...

Full description

Bibliographic Details
Main Authors: Maria João Sebastião, Michael Hoffman, José Escandell, Fatemeh Tousi, Jin Zhang, Bruno Figueroa, Christine DeMaria, Patrícia Gomes-Alves
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Biomedicines
Subjects:
multispecific antibodies
mispairing
transcriptomics
proteomics
CHO cells
Online Access:https://www.mdpi.com/2227-9059/11/11/2890

Internet

https://www.mdpi.com/2227-9059/11/11/2890

Similar Items