Current Epidemiology of Pneumocystis Pneumonia

Pneumocystis pneumonia (PCP) has historically been one of the leading causes of disease among persons with AIDS. The introduction of highly active antiretroviral therapy in industrialized nations has brought about dramatic declines in the incidence of AIDS-associated complications, including PCP. In...

Full description

Bibliographic Details
Main Authors: Alison Morris, Jens D. Lundgren, Henry Masur, Peter D. Walzer, Debra L. Hanson, Toni Frederick, Laurence Huang, Charles B. Beard, Jonathan E. Kaplan
Format: Article
Language:English
Published: Centers for Disease Control and Prevention 2004-10-01
Series:Emerging Infectious Diseases
Subjects:
Online Access:https://wwwnc.cdc.gov/eid/article/10/10/03-0985_article
_version_ 1811270671160836096
author Alison Morris
Jens D. Lundgren
Henry Masur
Peter D. Walzer
Debra L. Hanson
Toni Frederick
Laurence Huang
Charles B. Beard
Jonathan E. Kaplan
author_facet Alison Morris
Jens D. Lundgren
Henry Masur
Peter D. Walzer
Debra L. Hanson
Toni Frederick
Laurence Huang
Charles B. Beard
Jonathan E. Kaplan
author_sort Alison Morris
collection DOAJ
description Pneumocystis pneumonia (PCP) has historically been one of the leading causes of disease among persons with AIDS. The introduction of highly active antiretroviral therapy in industrialized nations has brought about dramatic declines in the incidence of AIDS-associated complications, including PCP. In the adult population, the incidence of PCP has significantly decreased, but it remains among the most common AIDS-defining infections. Similar declines have been documented in the pediatric population. In much of the developing world, PCP remains a significant health problem, although its incidence among adults in sub-Saharan Africa has been debated. This review discusses the epidemiology of PCP during the current era of the AIDS epidemic. Although fewer cases of PCP occur in the industrialized countries, increasing drug-resistant HIV infections, possible drug-resistant PCP, and to the tremendous number of AIDS cases in developing countries make this disease of continued public health importance.
first_indexed 2024-04-12T22:06:15Z
format Article
id doaj.art-6006c85f910e481881d62897f2a00036
institution Directory Open Access Journal
issn 1080-6040
1080-6059
language English
last_indexed 2024-04-12T22:06:15Z
publishDate 2004-10-01
publisher Centers for Disease Control and Prevention
record_format Article
series Emerging Infectious Diseases
spelling doaj.art-6006c85f910e481881d62897f2a000362022-12-22T03:14:55ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592004-10-0110101713172010.3201/eid1010.030985Current Epidemiology of Pneumocystis PneumoniaAlison MorrisJens D. LundgrenHenry MasurPeter D. WalzerDebra L. HansonToni FrederickLaurence HuangCharles B. BeardJonathan E. KaplanPneumocystis pneumonia (PCP) has historically been one of the leading causes of disease among persons with AIDS. The introduction of highly active antiretroviral therapy in industrialized nations has brought about dramatic declines in the incidence of AIDS-associated complications, including PCP. In the adult population, the incidence of PCP has significantly decreased, but it remains among the most common AIDS-defining infections. Similar declines have been documented in the pediatric population. In much of the developing world, PCP remains a significant health problem, although its incidence among adults in sub-Saharan Africa has been debated. This review discusses the epidemiology of PCP during the current era of the AIDS epidemic. Although fewer cases of PCP occur in the industrialized countries, increasing drug-resistant HIV infections, possible drug-resistant PCP, and to the tremendous number of AIDS cases in developing countries make this disease of continued public health importance.https://wwwnc.cdc.gov/eid/article/10/10/03-0985_articlePneumocystis jiroveciiPneumocystis pneumoniaPCPepidemiologyHIVhighly active antiretroviral therapy
spellingShingle Alison Morris
Jens D. Lundgren
Henry Masur
Peter D. Walzer
Debra L. Hanson
Toni Frederick
Laurence Huang
Charles B. Beard
Jonathan E. Kaplan
Current Epidemiology of Pneumocystis Pneumonia
Emerging Infectious Diseases
Pneumocystis jirovecii
Pneumocystis pneumonia
PCP
epidemiology
HIV
highly active antiretroviral therapy
title Current Epidemiology of Pneumocystis Pneumonia
title_full Current Epidemiology of Pneumocystis Pneumonia
title_fullStr Current Epidemiology of Pneumocystis Pneumonia
title_full_unstemmed Current Epidemiology of Pneumocystis Pneumonia
title_short Current Epidemiology of Pneumocystis Pneumonia
title_sort current epidemiology of pneumocystis pneumonia
topic Pneumocystis jirovecii
Pneumocystis pneumonia
PCP
epidemiology
HIV
highly active antiretroviral therapy
url https://wwwnc.cdc.gov/eid/article/10/10/03-0985_article
work_keys_str_mv AT alisonmorris currentepidemiologyofpneumocystispneumonia
AT jensdlundgren currentepidemiologyofpneumocystispneumonia
AT henrymasur currentepidemiologyofpneumocystispneumonia
AT peterdwalzer currentepidemiologyofpneumocystispneumonia
AT debralhanson currentepidemiologyofpneumocystispneumonia
AT tonifrederick currentepidemiologyofpneumocystispneumonia
AT laurencehuang currentepidemiologyofpneumocystispneumonia
AT charlesbbeard currentepidemiologyofpneumocystispneumonia
AT jonathanekaplan currentepidemiologyofpneumocystispneumonia