Case report: Myocarditis with nonsustained ventricular tachycardia following COVID-19 mRNA vaccination in a female adolescent
Children with underlying medical conditions potentially develop severe illness from Coronavirus disease 2019 (COVID-19). The use of vaccines against COVID-19 is currently recommended for the pediatric population. The COVID-19 vaccine has a temporal association with the occurrence of myocarditis. Alt...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-11-01
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| Series: | Frontiers in Pediatrics |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fped.2022.995167/full |
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| author | Jeongho Han Joowon Lee Sujin Choi Hyunju Lee Hyunju Lee Young Hwan Song |
| author_facet | Jeongho Han Joowon Lee Sujin Choi Hyunju Lee Hyunju Lee Young Hwan Song |
| author_sort | Jeongho Han |
| collection | DOAJ |
| description | Children with underlying medical conditions potentially develop severe illness from Coronavirus disease 2019 (COVID-19). The use of vaccines against COVID-19 is currently recommended for the pediatric population. The COVID-19 vaccine has a temporal association with the occurrence of myocarditis. Although most patients with COVID-19 vaccination-associated myocarditis (C-VAM) exhibit a mild clinical course and rapid recovery, C-VAM potentially causes electrical instability and sudden cardiac death. Herein, we report the case of a 17-year-old woman who presented with chest pain and syncope following the first dose of the messenger RNA COVID-19 vaccine. The patient's heart function was impaired, and nonsustained ventricular tachycardia was frequent. Cardiac magnetic resonance (CMR) imaging satisfied the criteria for myocarditis. Despite the administration of immunomodulatory drugs, the patient's heart function was not fully restored, and the concentration of cardiac enzymes remained above the normal range. Persistence of late gadolinium enhancement was observed on short-term follow-up CMR imaging. Although most patients with C-VAM exhibit mild symptoms, significant cardiac arrhythmias potentially occur. Furthermore, some patients with C-VAM demonstrate prolonged impaired heart function and sustained late gadolinium enhancement on follow-up CMR imaging. Therefore, monitoring of electrical and functional cardiac abnormalities in patients with C-VAM is crucial and the long-term outcomes and prognosis of patients with C-VAM require further investigation. |
| first_indexed | 2024-04-13T12:43:42Z |
| format | Article |
| id | doaj.art-6009e742263e43b1b1e4e3180eca3e6f |
| institution | Directory Open Access Journal |
| issn | 2296-2360 |
| language | English |
| last_indexed | 2024-04-13T12:43:42Z |
| publishDate | 2022-11-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Pediatrics |
| spelling | doaj.art-6009e742263e43b1b1e4e3180eca3e6f2022-12-22T02:46:26ZengFrontiers Media S.A.Frontiers in Pediatrics2296-23602022-11-011010.3389/fped.2022.995167995167Case report: Myocarditis with nonsustained ventricular tachycardia following COVID-19 mRNA vaccination in a female adolescentJeongho Han0Joowon Lee1Sujin Choi2Hyunju Lee3Hyunju Lee4Young Hwan Song5Department of Pediatrics, Seoul National University Children's Hospital, Seoul, South KoreaDepartment of Pediatrics, Seoul National University Bundang Hospital, Seongnam, South KoreaDepartment of Pediatrics, Seoul National University Bundang Hospital, Seongnam, South KoreaDepartment of Pediatrics, Seoul National University Bundang Hospital, Seongnam, South KoreaDepartment of Pediatrics, Seoul National University College of Medicine, Seoul, South KoreaDepartment of Pediatrics, Seoul National University Bundang Hospital, Seongnam, South KoreaChildren with underlying medical conditions potentially develop severe illness from Coronavirus disease 2019 (COVID-19). The use of vaccines against COVID-19 is currently recommended for the pediatric population. The COVID-19 vaccine has a temporal association with the occurrence of myocarditis. Although most patients with COVID-19 vaccination-associated myocarditis (C-VAM) exhibit a mild clinical course and rapid recovery, C-VAM potentially causes electrical instability and sudden cardiac death. Herein, we report the case of a 17-year-old woman who presented with chest pain and syncope following the first dose of the messenger RNA COVID-19 vaccine. The patient's heart function was impaired, and nonsustained ventricular tachycardia was frequent. Cardiac magnetic resonance (CMR) imaging satisfied the criteria for myocarditis. Despite the administration of immunomodulatory drugs, the patient's heart function was not fully restored, and the concentration of cardiac enzymes remained above the normal range. Persistence of late gadolinium enhancement was observed on short-term follow-up CMR imaging. Although most patients with C-VAM exhibit mild symptoms, significant cardiac arrhythmias potentially occur. Furthermore, some patients with C-VAM demonstrate prolonged impaired heart function and sustained late gadolinium enhancement on follow-up CMR imaging. Therefore, monitoring of electrical and functional cardiac abnormalities in patients with C-VAM is crucial and the long-term outcomes and prognosis of patients with C-VAM require further investigation.https://www.frontiersin.org/articles/10.3389/fped.2022.995167/fulladolescentmyocarditisCOVID-19vaccinecase report |
| spellingShingle | Jeongho Han Joowon Lee Sujin Choi Hyunju Lee Hyunju Lee Young Hwan Song Case report: Myocarditis with nonsustained ventricular tachycardia following COVID-19 mRNA vaccination in a female adolescent Frontiers in Pediatrics adolescent myocarditis COVID-19 vaccine case report |
| title | Case report: Myocarditis with nonsustained ventricular tachycardia following COVID-19 mRNA vaccination in a female adolescent |
| title_full | Case report: Myocarditis with nonsustained ventricular tachycardia following COVID-19 mRNA vaccination in a female adolescent |
| title_fullStr | Case report: Myocarditis with nonsustained ventricular tachycardia following COVID-19 mRNA vaccination in a female adolescent |
| title_full_unstemmed | Case report: Myocarditis with nonsustained ventricular tachycardia following COVID-19 mRNA vaccination in a female adolescent |
| title_short | Case report: Myocarditis with nonsustained ventricular tachycardia following COVID-19 mRNA vaccination in a female adolescent |
| title_sort | case report myocarditis with nonsustained ventricular tachycardia following covid 19 mrna vaccination in a female adolescent |
| topic | adolescent myocarditis COVID-19 vaccine case report |
| url | https://www.frontiersin.org/articles/10.3389/fped.2022.995167/full |
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