Asymtomatic essential thrombocythemia in a child: a rare case report
Essential thrombocythemia is a rare myeloproliferative disorder in pediatrics. This myeloproliferative disorder is charactherized by thrombocytosis and hyperplasia of megakaryocytes in the bone marrow. Other cell lines are not involved.JAK2V617Fmutations has been identified in approximately half the...
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| Format: | Article |
| Language: | English |
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Tehran University of Medical Sciences
2013-06-01
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| Series: | International Journal of Hematology-Oncology and Stem Cell Research |
| Subjects: | |
| Online Access: | https://ijhoscr.tums.ac.ir/index.php/ijhoscr/article/view/453 |
| _version_ | 1797720620931219456 |
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| author | Majid Vafaie Kaveh Jaseb Majid Ghanavat Mohamad Pedram Tooran Rahiminia |
| author_facet | Majid Vafaie Kaveh Jaseb Majid Ghanavat Mohamad Pedram Tooran Rahiminia |
| author_sort | Majid Vafaie |
| collection | DOAJ |
| description | Essential thrombocythemia is a rare myeloproliferative disorder in pediatrics. This myeloproliferative disorder is charactherized by thrombocytosis and hyperplasia of megakaryocytes in the bone marrow. Other cell lines are not involved.JAK2V617Fmutations has been identified in approximately half the patients with this disorder. We describe a 12-year-old boy with essential throbocythemia. The patient had a persistent thrombocytosis over 600x109 /L and the time of diagnosis, his platelet count ranged between 900x109and 2150x109/L. Megakaryocytes in the bone marrow were increased in number. The chromosomal analysis was normal and bcr/abl rearrangement was negative. He remained asymptomatic throughout the follow-up period. |
| first_indexed | 2024-03-12T09:22:08Z |
| format | Article |
| id | doaj.art-600cdbc241474505934a69f993fbfb17 |
| institution | Directory Open Access Journal |
| issn | 2008-2207 |
| language | English |
| last_indexed | 2024-03-12T09:22:08Z |
| publishDate | 2013-06-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | International Journal of Hematology-Oncology and Stem Cell Research |
| spelling | doaj.art-600cdbc241474505934a69f993fbfb172023-09-02T14:24:50ZengTehran University of Medical SciencesInternational Journal of Hematology-Oncology and Stem Cell Research2008-22072013-06-0172Asymtomatic essential thrombocythemia in a child: a rare case reportMajid Vafaie0Kaveh Jaseb1Majid Ghanavat2Mohamad Pedram3Tooran Rahiminia4Research Center of Thalassemia & Hemoglobinopathy, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.Research Center of Thalassemia & Hemoglobinopathy, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.Research Center of Thalassemia & Hemoglobinopathy, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.Research Center of Thalassemia & Hemoglobinopathy, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.Research Center of Thalassemia & Hemoglobinopathy, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.Essential thrombocythemia is a rare myeloproliferative disorder in pediatrics. This myeloproliferative disorder is charactherized by thrombocytosis and hyperplasia of megakaryocytes in the bone marrow. Other cell lines are not involved.JAK2V617Fmutations has been identified in approximately half the patients with this disorder. We describe a 12-year-old boy with essential throbocythemia. The patient had a persistent thrombocytosis over 600x109 /L and the time of diagnosis, his platelet count ranged between 900x109and 2150x109/L. Megakaryocytes in the bone marrow were increased in number. The chromosomal analysis was normal and bcr/abl rearrangement was negative. He remained asymptomatic throughout the follow-up period.https://ijhoscr.tums.ac.ir/index.php/ijhoscr/article/view/453Myeloproliferative disorderThrombocythemia |
| spellingShingle | Majid Vafaie Kaveh Jaseb Majid Ghanavat Mohamad Pedram Tooran Rahiminia Asymtomatic essential thrombocythemia in a child: a rare case report International Journal of Hematology-Oncology and Stem Cell Research Myeloproliferative disorder Thrombocythemia |
| title | Asymtomatic essential thrombocythemia in a child: a rare case report |
| title_full | Asymtomatic essential thrombocythemia in a child: a rare case report |
| title_fullStr | Asymtomatic essential thrombocythemia in a child: a rare case report |
| title_full_unstemmed | Asymtomatic essential thrombocythemia in a child: a rare case report |
| title_short | Asymtomatic essential thrombocythemia in a child: a rare case report |
| title_sort | asymtomatic essential thrombocythemia in a child a rare case report |
| topic | Myeloproliferative disorder Thrombocythemia |
| url | https://ijhoscr.tums.ac.ir/index.php/ijhoscr/article/view/453 |
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